Mechanisms in cardiac fibroblast growth: an obligate role for Skp2 and FOXO3a in ERK1/2 MAPK-dependent regulation of p27kip1

FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma

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cIAP-2 protects cardiac fibroblasts from oxidative damage: An obligate regulatory role for ERK1/2 MAPK and NF-κB

(2013) Linda Philip et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

FOXO3a/p27kip1expression and essential role after acute spinal cord injury in adult rat

(2012) Shuangwei Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

(2012) Karl T. Weber et al.   Nature Reviews Cardiology

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

(2012) Shauna A Henley et al.   Cell Division

Bimodal regulation of FoxO3 by AKT and 14-3-3

(2011) Melissa Dobson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization

(2011) Tarig Bashir et al.   CELL CYCLE

NF-κB inhibition compromises cardiac fibroblast viability under hypoxia

(2011) M. Sangeetha et al.   EXPERIMENTAL CELL RESEARCH

p38 MAPK regulates G1-S transition in hypoxic cardiac fibroblasts

(2011) Malini S. Pillai et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The FoxO Family in Cardiac Function and Dysfunction

(2010) Sarah M. Ronnebaum et al.   Annual Review of Physiology

High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells

(2010) Theresia R Kress et al.   Cell Communication and Signaling

Regulation of Skp2 Levels by the Pim-1 Protein Kinase

(2010) Bo Cen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The origin of fibroblasts and mechanism of cardiac fibrosis

(2010) Guido Krenning et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protein kinase C in heart failure: a therapeutic target?

(2009) S. S. Palaniyandi et al.   CARDIOVASCULAR RESEARCH

Cardiac Fibroblast

(2009) Colby A. Souders et al.   CIRCULATION RESEARCH

A New Fork for Clinical Application: Targeting Forkhead Transcription Factors in Cancer

(2009) J.-Y. Yang et al.   CLINICAL CANCER RESEARCH

Mitogenic Regulation of p27Kip1Gene Is Mediated by AP-1 Transcription Factors

(2009) Ekta Khattar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

(2009) Hui-Kuan Lin et al.   NATURE CELL BIOLOGY

The Expression and Prognosis of FOXO3a and Skp2 in Human Hepatocellular Carcinoma

(2009) Mudan Lu et al.   PATHOLOGY & ONCOLOGY RESEARCH

Cardiac fibroblasts: At the heart of myocardial remodeling

(2009) Karen E. Porter et al.   PHARMACOLOGY & THERAPEUTICS

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

(2009) Daming Gao et al.   Cell Division

Age-dependent FOXO regulation of p27Kip1 expression via a conserved binding motif in rat muscle precursor cells

(2008) Simon J. Lees et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibitory crosstalk between ERK and AMPK in the growth and proliferation of cardiac fibroblasts

(2008) Jianhai Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

(2008) Q. Chen et al.   BLOOD

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Forkhead box-O transcription factor: critical conductors of cancer's fate

(2008) C. Weidinger et al.   ENDOCRINE-RELATED CANCER

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY