Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats

Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats

(2013) Melissa A. Linden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Metformin modifies the exercise training effects on risk factors for cardiovascular disease in impaired glucose tolerant adults

(2013) Steven K. Malin et al.   Obesity

PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion

(2012) E. Matthew Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effects of Aerobic Versus Resistance Exercise Without Caloric Restriction on Abdominal Fat, Intrahepatic Lipid, and Insulin Sensitivity in Obese Adolescent Boys: A Randomized, Controlled Trial

(2012) S. Lee et al.   DIABETES

Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF rats

(2012) Nathan T. Jenkins et al.   JOURNAL OF APPLIED PHYSIOLOGY

Short-term exercise reduces markers of hepatocyte apoptosis in nonalcoholic fatty liver disease

(2012) Ciaran E. Fealy et al.   JOURNAL OF APPLIED PHYSIOLOGY

The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2

(2012) Jenson Qi et al.   JOURNAL OF LIPID RESEARCH

Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction

(2011) Jeffrey D Browning et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model

(2011) R. Scott Rector et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Metformin Inhibits Nuclear Receptor TR4-Mediated Hepatic Stearoyl-CoA Desaturase 1 Gene Expression With Altered Insulin Sensitivity

(2011) E. Kim et al.   DIABETES

Independent and Combined Effects of Exercise Training and Metformin on Insulin Sensitivity in Individuals With Prediabetes

(2011) S. K. Malin et al.   DIABETES CARE

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C

(2011) M. E. Miquilena-Colina et al.   GUT

Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease

(2011) Shelby Sullivan et al.   HEPATOLOGY

Does physical inactivity cause nonalcoholic fatty liver disease?

(2011) R. Scott Rector et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mice Lacking TR4 Nuclear Receptor Develop Mitochondrial Myopathy with Deficiency in Complex I

(2011) Su Liu et al.   MOLECULAR ENDOCRINOLOGY

Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats

(2010) R. Scott Rector et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individuals

(2010) Carrie G. Sharoff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Swimming training beneficial effects in a mice model of nonalcoholic fatty liver disease

(2010) Alini Schultz et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

(2010) Brent A. Neuschwander-Tetri   HEPATOLOGY

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

(2010) R. Scott Rector et al.   JOURNAL OF HEPATOLOGY

Effects of Metformin and Weight Loss on Serum Alanine Aminotransferase Activity in the Diabetes Prevention Program

(2010) Jonathan Krakoff et al.   Obesity

Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids

(2009) Claudio J. Villanueva et al.   HEPATOLOGY

Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss

(2009) Nathan A. Johnson et al.   HEPATOLOGY

Effect of 6-month nutritional intervention on non-alcoholic fatty liver disease

(2009) Maria Cristina Elias et al.   NUTRITION

TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation

(2009) S. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats

(2008) R. Scott Rector et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes

(2008) Takayuki Matsumoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effect of Exercise on 24-Month Weight Loss Maintenance in Overweight Women

(2008) John M. Jakicic   ARCHIVES OF INTERNAL MEDICINE

Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats

(2008) R. Scott Rector et al.   JOURNAL OF PHYSIOLOGY-LONDON

Weight Regain Is Related to Decreases in Physical Activity during Weight Loss

(2008) XUEWEN WANG et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Effect of 6-Month Calorie Restriction and Exercise on Serum and Liver Lipids and Markers of Liver Function

(2008) D. Enette Larson-Meyer et al.   Obesity

Non-alcoholic fatty liver disease and the metabolic syndrome: An update

(2008) R Scott Rector et al.   WORLD JOURNAL OF GASTROENTEROLOGY