Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice

SIRT1, metabolism and cancer

(2011) John R.P. Knight et al.   CURRENT OPINION IN ONCOLOGY

Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice

(2011) Z. Xie et al.   DIABETES

Dietary Leucine - An Environmental Modifier of Insulin Resistance Acting on Multiple Levels of Metabolism

(2011) Yazmin Macotela et al.   PLoS One

Mitochondrial dysfunction in obesity

(2011) Juan C Bournat et al.   Current Opinion in Endocrinology Diabetes and Obesity

Enhanced Tyrosine Nitration of Prostacyclin Synthase Is Associated with Increased Inflammation in Atherosclerotic Carotid Arteries from Type 2 Diabetic Patients

(2010) Chaoyong He et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial Biogenesis and Peroxisome Proliferator-Activated Receptor-  Coactivator-1  (PGC-1 ) Deacetylation by Physical Activity: Intact Adipocytokine Signaling Is Required

(2010) L. Li et al.   DIABETES

Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease

(2010) Jun Ren et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Short-term adenosine monophosphate–activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside treatment increases the sirtuin 1 protein expression in skeletal muscle

(2010) Masataka Suwa et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A Kinase-Independent Role for Unoccupied Insulin and IGF-1 Receptors in the Control of Apoptosis

(2010) J. Boucher et al.   Science Signaling

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Leucine Supplementation of Drinking Water Does Not Alter Susceptibility to Diet-Induced Obesity in Mice

(2009) Ali Nairizi et al.   JOURNAL OF NUTRITION

Identification of the Serine 307 of LKB1 as a Novel Phosphorylation Site Essential for Its Nucleocytoplasmic Transport and Endothelial Cell Angiogenesis

(2009) Z. Xie et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Protein deacetylation by SIRT1: An emerging key post-translational modification in metabolic regulation

(2009) Jiujiu Yu et al.   PHARMACOLOGICAL RESEARCH

Sirtuins: Novel targets for metabolic disease in drug development

(2008) Wei-jian Jiang   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism

(2008) Thien T. Tran et al.   Cell Metabolism

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

Phosphorylation of LKB1 at Serine 428 by Protein Kinase C-ζ Is Required for Metformin-Enhanced Activation of the AMP-Activated Protein Kinase in Endothelial Cells

(2008) Zhonglin Xie et al.   CIRCULATION

Cannabinoid Type 1 Receptor Blockade Promotes Mitochondrial Biogenesis Through Endothelial Nitric Oxide Synthase Expression in White Adipocytes

(2008) L. Tedesco et al.   DIABETES

Structure/function relationships underlying regulation of FOXO transcription factors

(2008) T Obsil et al.   ONCOGENE