Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan

Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice

(2012) Vladimir N. Anisimov et al.   CELL CYCLE

The cytoprotective role of the Keap1–Nrf2 pathway

(2011) Liam Baird et al.   ARCHIVES OF TOXICOLOGY

Nrf2: control of sensitivity to carcinogens

(2011) Stephen L. Slocum et al.   ARCHIVES OF TOXICOLOGY

Pleiotropic effects of growth hormone signaling in aging

(2011) Andrzej Bartke   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Small molecule modulators of antioxidant response pathway

(2010) Wooyoung Hur et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice

(2010) Jacob A. Panici et al.   FASEB JOURNAL

Hepatic response to oxidative injury in long-lived Ames dwarf mice

(2010) Liou Y. Sun et al.   FASEB JOURNAL

Life Extension by Diet Restriction and N-Acetyl-L-Cysteine in Genetically Heterogeneous Mice

(2010) K. Flurkey et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

(2010) Richard A. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

NRF2, cancer and calorie restriction

(2010) A Martín-Montalvo et al.   ONCOGENE

Single-gene mutations and healthy ageing in mammals

(2010) A. Bartke   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Xenobiotic Metabolism, Disposition, and Regulation by Receptors: From Biochemical Phenomenon to Predictors of Major Toxicities

(2010) C. J. Omiecinski et al.   TOXICOLOGICAL SCIENCES

Nrf2: friend or foe for chemoprevention?

(2009) T. W. Kensler et al.   CARCINOGENESIS

Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age

(2009) L. Sun et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Long-Lived Ames Dwarf Mice Are Resistant to Chemical Stressors

(2009) Alex F. Bokov et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Nrf2 Signaling, a Mechanism for Cellular Stress Resistance in Long-Lived Mice

(2009) S. F. Leiser et al.   MOLECULAR AND CELLULAR BIOLOGY

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Design of aging intervention studies: the NIA interventions testing program

(2008) N. L. Nadon et al.   AGE

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

(2008) Gerasimos P. Sykiotis et al.   DEVELOPMENTAL CELL

Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction

(2008) K. J. Pearson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative analysis of microarray data identifies common responses to caloric restriction among mouse tissues

(2007) William R. Swindell   MECHANISMS OF AGEING AND DEVELOPMENT