Article
Oncology
Liping Fan, Qiuyan Lin, Xiaoling Huang, Danhui Fu, Haobo Huang
Summary: High pretreatment serum FFA levels are associated with worse clinical features and prognosis in DLBCL patients, indicating a potentially negative impact on survival outcomes.
Article
Engineering, Electrical & Electronic
Sharu Theresa Jose, Osvaldo Simeone
Summary: This lecture note aims to review the problem of free energy minimization as a unified framework underlying maximum entropy modeling, generalized Bayesian inference, learning with latent variables, statistical learning analysis, and local optimization. It introduces free energy minimization as a thermodynamic principle historically, and describes it mathematically in the context of Fenchel duality. The applications to modeling, inference, learning, and optimization are covered, starting from basic principles.
IEEE SIGNAL PROCESSING MAGAZINE
(2021)
Article
Biotechnology & Applied Microbiology
Hideo Maruyama, Keito Fukuchi, Hideshi Seki
Summary: The aim of this study is to develop a simulation model for the fractionation of fatty acid methyl esters (FAME) using urea complexation. The different complexation behaviors of SFAME, MFAME, and PFAME were observed, and a fractionation model was proposed to explain the observed phenomena.
BIOCHEMICAL ENGINEERING JOURNAL
(2022)
Article
Multidisciplinary Sciences
Agata Kaczmarek, Mieczyslawa Bogus
Summary: Insects, with over one million described species, play important ecological roles, such as pollinating plants and influencing agriculture. They also have significant impacts on human health as disease vectors and in medical treatments. In addition, insects are used in forensic science and research as model organisms.
Article
Energy & Fuels
Hao Sen Siow, Kumar Sudesh, Paramasivam Murugan, Shangeetha Ganesan
Summary: The study focused on the characteristics of mealworm oil, such as its high oil content and primary fatty acids. Through acid-catalyzed esterification, the FFA content was successfully reduced to below 1%, meeting the standards for biodiesel production.
Article
Psychiatry
Anh Thi Phuong Le, Yuko Higuchi, Tomiki Sumiyoshi, Hiroko Itoh, Daiki Sasabayashi, Tsutomu Takahashi, Michio Suzuki
Summary: Abnormalities in membrane phospholipids are considered to be one of the underlying causes of schizophrenia. This study examines the fatty acid composition of erythrocyte membranes in individuals at-risk of mental illness and those with a first-episode of schizophrenia, and links it to clinical characteristics. The results show that certain fatty acids were lower in both groups compared to healthy individuals, while nervonic acid levels were significantly higher. Oleic acid and nervonic acid levels were also associated with specific symptoms in both groups. These findings suggest that abnormal fatty acid compositions may be markers of vulnerability in the early stages of schizophrenia and in individuals at-risk of psychosis.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Engineering, Environmental
Pantea Moradi, Majid Saidi, Ali Taheri Najafabadi
Summary: This study evaluated the efficiency of producing biodiesel from biomass containing free fatty acids using the electrolysis method, investigating the impact of various operating parameters on the yield. The results showed that electrolysis could achieve a high biodiesel production yield under specific conditions.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2021)
Review
Biochemistry & Molecular Biology
Maxwell Duah, Kexin Zhang, Yiwen Liang, Vivian Adiila Ayarick, Kailin Xu, Bin Pan
Summary: Fatty acid metabolism is vital for energy supply and immune regulation. Free fatty acids interact with cell surface receptors called free fatty acid receptors (FFARs) to exert their effects through intracellular signaling pathways. FFAR4, also known as G-protein coupled receptor 120 (GPR120), has been identified as the primary receptor for omega-3 polyunsaturated fatty acids (w-3 PUFAs) and shows promise in treating metabolic and inflammatory disorders. This review summarizes the immune regulatory functions of w-3 PUFAs and FFAR4 in immune cells and immune-related diseases, as well as their potential involvement in other inflammatory disorders.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2023)
Article
Agriculture, Dairy & Animal Science
R. Rodriguez-Sanchez, A. Tres, R. Sala, M. D. Soler, F. Guardiola, A. C. Barroeta
Summary: The study demonstrates that the majority of fatty acids are absorbed in the jejunum regardless of dietary fat source, with higher absorption efficiency in broilers fed with unsaturated diets. Dietary FFA levels can affect the fatty acid absorption process, while including acid oils up to 35% in broiler diets does not have a negative impact on absorption.
Article
Chemistry, Physical
David Novak, Martina Zatloukalova, Lukas Jedinak, Bara Komarkova, Martin Kabelac, Jan Vacek
Summary: The study shows that the complex formed by 8-cyclodextrin (8-CD) and NO2-OA is more stable in aqueous solution, while NO2-OA alone is less stable. Under solid-state conditions, the degradation rate of 8-CD/NO2-OA is slower and has a longer storage time.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Reproductive Biology
Eri Furukawa, Zhen Chen, Hiroki Ueshiba, Yue Wu, Hitoshi Chiba, Yojiro Yanagawa, Seiji Katagiri, Masashi Nagano, Shu-Ping Hui
Summary: High circulating FFA concentrations postpartum may impact the quality of oocytes in postpartum cows, contributing to low fertility.
Article
Agriculture, Dairy & Animal Science
M. Palomar, M. D. Soler, A. Tres, A. C. Barroeta, M. Munoz-Nunez, C. Garces-Narro
Summary: The present study aimed to evaluate the effects of dietary free fatty acid (FFA) content and the degree of saturation on egg quality, yolk fatty acid (FA) profile, and yolk cholesterol content. The results showed that the effect of varying dietary FFA levels on egg quality and yolk composition was not as significant as the differences in dietary fat sources.
Article
Agriculture, Dairy & Animal Science
M. Palomar, M. D. Soler, A. Tres, A. C. Barroeta, M. Munoz-Nunez, C. Garces-Narro
Summary: The aim of this study was to evaluate the effects of dietary free fatty acid (FFA) content and the degree of saturation on egg quality, yolk fatty acid (FA) profile, and yolk cholesterol content. The results showed that the variation in dietary FFA level had smaller effects on egg quality and yolk composition compared to the dietary fat source.
Article
Biochemistry & Molecular Biology
Kaili Cui, Lichao Zhang, Xiaoqin La, Haili Wu, Ruipeng Yang, Hanqing Li, Zhuoyu Li
Summary: This study investigated the mechanism underlying the impact of ferulic acid and p-coumaric acid on non-alcoholic fatty liver disease (NAFLD). The results suggested that these acids improve NAFLD by inhibiting free fatty acid uptake and may serve as potential dietary supplements and drugs for preventing NAFLD.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Food Science & Technology
Muhammad Syahmeer How, Nazimah Hamid, Ye Liu, Kevin Kantono, Indrawati Oey, Mingfei Wang
Summary: This study investigated the effect of high pressure processing on the fatty acids and amino acids content in New Zealand clams. Different pressure levels and holding times were applied, and the results showed that lower pressure and shorter holding time resulted in the least changes in amino and fatty acids content of clams.
Editorial Material
Endocrinology & Metabolism
Min-Kyung Lee, Kyungdo Han, Hyuk-Sang Kwon
Article
Endocrinology & Metabolism
Ji-Yeon Park, Kyungdo Han, Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon, Mee Kyoung Kim, Seung-Hwan Lee
Summary: This study found a linear relationship between cumulative exposure to high gamma-GTP level and risk of diabetes, suggesting that monitoring and lowering gamma-GTP level should be considered for prevention of diabetes in the general population.
ENDOCRINOLOGY AND METABOLISM
(2022)
Article
Endocrinology & Metabolism
Jinyoung Kim, Jeonghoon Ha, Chaiho Jeong, Jeongmin Lee, Yejee Lim, Kwanhoon Jo, Mee Kyoung Kim, Hyuk-Sang Kwon, Ki-Ho Song, Ki-Hyun Baek
Summary: This study investigated the relationship between lipid profiles and bone mineral density (BMD) in older adults. The results showed a significant inverse association between serum triglycerides and BMD, and this relationship is thought to correlate with vitamin D status among older adults.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Medicine, General & Internal
Hyunah Kim, Da Young Jung, Seung-Hwan Lee, Jae-Hyoung Cho, Hyeon Woo Yim, Hun-Sung Kim
Summary: This study examined the relationship between glycemic control and cardiovascular disease risk in patients with type 2 diabetes. The results suggest that controlling glucose levels during early diabetes may be more important than reducing glycemic variability.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Gastroenterology & Hepatology
Han Hee Lee, Kyu-na Lee, Jin Su Kim, Dae Young Cheung, Hyuk-Sang Kwon, Bo-In Lee, Young-Seok Cho, Soo-Heon Park, Kyungdo Han, Jin Il Kim
Summary: This study investigated the association between changes in physical activity status and the development of colorectal cancer in patients with diabetes. The results showed that patients with diabetes who remained physically active had the lowest risk of developing colorectal cancer, while those who changed from inactive to active also had a reduced risk.
COLORECTAL DISEASE
(2023)
Article
Biochemistry & Molecular Biology
Oak-Kee Hong, Eun Sook Kim, Jang-Won Son, Sung-Rae Kim, Soon Jib Yoo, Hyuk-Sang Kwon, Seong-Su Lee
Summary: Alcohol consumption exacerbates liver abnormalities and induces liver injury in early diabetic or prediabetic rats. However, the response to alcohol differs between prediabetic and diabetic rats. In prediabetic rats, alcohol induced liver steatosis and hepatitis, but had mild effects on inflammation.
JOURNAL OF CELLULAR BIOCHEMISTRY
(2023)
Editorial Material
Endocrinology & Metabolism
Jin Yu, Jae-Hyoung Cho, Seung-Hwan Lee
JOURNAL OF DIABETES INVESTIGATION
(2023)
Article
Medicine, General & Internal
Jinyoung Kim, Kyungdo Han, Mee Kyoung Kim, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
Summary: Despite a similar examination rate, there has been a re-increasing trend in thyroid cancer since 2015, especially among young adults. A study using data from the Korean National Health Insurance Service found that cumulative exposure to metabolic syndrome was associated with an increased risk of thyroid cancer in young adults. The risk increased with the number of diagnoses of metabolic syndrome across multiple health examinations.
KOREAN JOURNAL OF INTERNAL MEDICINE
(2023)
Letter
Endocrinology & Metabolism
Se-Won Lee, Kyungdo Han, Hyuk-Sang Kwon
DIABETES & METABOLISM JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Hee Yeon Lee, Kyung-Do Han, In Sook Woo, Hyuk-Sang Kwon
Summary: The aim of this study was to determine the association of metabolic syndrome (MetS) with kidney cancer and the impact of age and gender on such an association. The study used the Korean National Health Insurance Service database to follow up 9,932,670 subjects who had check-ups in 2009 until the diagnosis of kidney cancer or death or until 2019. The results showed that kidney cancer was significantly associated with MetS, with a higher association in younger age groups and higher associations with obesity and central obesity in younger aged male population.
Article
Endocrinology & Metabolism
Seung-Hwan Lee, Jin Yu, Kyungdo Han, Seung Woo Lee, Sang Youn You, Hun -Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon, Mee Kyoung Kim
Summary: A risk model for predicting insulin-requiring GDM before pregnancy in Korean women was developed using data from 417,210 women. Six risk factors were identified and incorporated into a risk nomogram. The model showed a concordance index of 0.783, indicating its accuracy in predicting insulin-requiring GDM.
ENDOCRINOLOGY AND METABOLISM
(2023)
Article
Endocrinology & Metabolism
Jin Hwa Kim, Young Sang Lyu, Mee Kyoung Kim, Sang Yong Kim, Ki-Hyun Baek, Ki-Ho Song, Kyungdo Han, Hyuk-Sang Kwon
Summary: This study found that repeated detection of non-alcoholic fatty liver disease (NAFLD) increases the risk of type 2 diabetes in young adults, and the risk increases with the number of repeated detections.
DIABETES OBESITY & METABOLISM
(2023)
Editorial Material
Endocrinology & Metabolism
Seung-Hwan Lee
DIABETES & METABOLISM JOURNAL
(2023)
Editorial Material
Endocrinology & Metabolism
Seung-Hwan Lee
ENDOCRINOLOGY AND METABOLISM
(2023)
Article
Endocrinology & Metabolism
Jinyoung Kim, Bongseong Kim, Mee Kyoung Kim, Ki-Hyun Baek, Ki-Ho Song, Kyungdo Han, Hyuk-Sang Kwon
Summary: This study aimed to investigate the association between weight change and diabetes remission in patients with new-onset type 2 diabetes mellitus. The study found that weight loss within the first 2 years of treating type 2 diabetes was associated with diabetes remission, and the likelihood of remission increased with greater weight loss. Physicians should pay more attention to weight management, particularly for young and obese individuals with new-onset type 2 diabetes.
DIABETES OBESITY & METABOLISM
(2023)