A tale of two collagen receptors, integrin β1 and discoidin domain receptor 1, in epithelial cell differentiation

Discoidin Domain Receptor 1 Is a Major Mediator of Inflammation and Fibrosis in Obstructive Nephropathy

(2011) Dominique Guerrot et al.   AMERICAN JOURNAL OF PATHOLOGY

Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth

(2011) Michael S. Samuel et al.   CANCER CELL

DDR1 triggers epithelial cell differentiation by promoting cell adhesion through stabilization of E-cadherin

(2011) Yi-Chun Yeh et al.   MOLECULAR BIOLOGY OF THE CELL

Balancing forces: architectural control of mechanotransduction

(2011) Christopher C. DuFort et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transforming Growth Factor-β1 Induces Smad3-Dependent β1 Integrin Gene Expression in Epithelial-to-Mesenchymal Transition during Chronic Tubulointerstitial Fibrosis

(2010) Yi-Chun Yeh et al.   AMERICAN JOURNAL OF PATHOLOGY

Quantitative In vivo Imaging of the Effects of Inhibiting Integrin Signaling via Src and FAK on Cancer Cell Movement: Effects on E-cadherin Dynamics

(2010) M. Canel et al.   CANCER RESEARCH

Breast Cancer Cells in Three-dimensional Culture Display an Enhanced Radioresponse after Coordinate Targeting of Integrin  5 1 and Fibronectin

(2010) J.-M. Nam et al.   CANCER RESEARCH

An integrative view on the role of TGF-β in the progressive tubular deletion associated with chronic kidney disease

(2010) Omar García-Sánchez et al.   KIDNEY INTERNATIONAL

Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease

(2010) Oliver Gross et al.   MATRIX BIOLOGY

Integrin expression profiling identifies integrin alpha5 and beta1 as prognostic factors in early stage non-small cell lung cancer

(2010) Anne-Marie C Dingemans et al.   Molecular Cancer

Collective cell migration requires suppression of actomyosin at cell–cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6

(2010) Cristina Hidalgo-Carcedo et al.   NATURE CELL BIOLOGY

New pharmacological treatments for improving renal outcomes in diabetes

(2010) Anne-Emilie Declèves et al.   Nature Reviews Nephrology

DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading

(2009) Chau-Zen Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An Activating β1 Integrin Mutation Increases the Conversion of Benign to Malignant Skin Tumors

(2009) Manuela Ferreira et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

 1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity

(2009) X. Zhang et al.   DEVELOPMENT

Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts

(2009) Young Kim et al.   JOURNAL OF CELL BIOLOGY

Inhibition of Integrin-Linked Kinase Attenuates Renal Interstitial Fibrosis

(2009) Y. Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Endocytosis is required for E-cadherin redistribution at mature adherens junctions

(2009) S. de Beco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin  1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

(2009) T. Shibue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in DDR2 Gene Cause SMED with Short Limbs and Abnormal Calcifications

(2008) Ruth Bargal et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cdc42, Par6, and aPKC Regulate Arp2/3-Mediated Endocytosis to Control Local Adherens Junction Stability

(2008) Marios Georgiou et al.   CURRENT BIOLOGY

Drosophila Cip4 and WASp Define a Branch of the Cdc42-Par6-aPKC Pathway Regulating E-Cadherin Endocytosis

(2008) Andrea Leibfried et al.   CURRENT BIOLOGY

Integrin-linked kinase regulates E-cadherin expression through PARP-1

(2008) Timothy R. McPhee et al.   DEVELOPMENTAL DYNAMICS

Mechanisms of Fibrogenesis

(2008) Tatiana Kisseleva et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Discoidin domain receptor 1 activation suppresses α2β1integrin-dependent cell spreading through inhibition of Cdc42 activity

(2008) Yi-Chun Yeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

β1 Integrin deletion from the basal compartment of the mammary epithelium affects stem cells

(2008) Ilaria Taddei et al.   NATURE CELL BIOLOGY

Integrin β1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus

(2007) Keizo Kanasaki et al.   DEVELOPMENTAL BIOLOGY