Article
Oncology
Electra D. Paskett, Jennifer Le-Rademacher, Jill M. Oliveri, Heshan Liu, Drew K. Seisler, Jeffrey A. Sloan, Jane M. Armer, Michelle J. Naughton, Karen Hock, Michael Schwartz, Gary Unzeitig, Marianne Melnik, Lisa D. Yee, Gini F. Fleming, John R. Taylor, Charles Loprinzi
Summary: The study compared the impact of education-only intervention and education plus sleeve compression/exercise intervention on lymphedema incidence and range of motion in breast cancer patients. The results showed no significant difference in lymphedema-free rates between the two groups at 18 months, with better range of motion in the LEAP group.
Review
Oncology
Elena Munoz-Gomez, Anna Arnal-Gomez, Alba Lopez Cascon, Gemma Espi-Lopez
Summary: The purpose of this review is to evaluate the efficacy of aquatic therapeutic exercise in female breast cancer survivors for improving fatigue, pain, lymphedema, and quality of life. A systematic literature review was conducted, and ten randomized controlled trials with 606 participants were included. The results suggest that aquatic therapeutic exercise is effective in reducing fatigue, pain, and improving quality of life, although the effects on lymphedema remain uncertain. The methodological quality of the studies was high, and no adverse effects were reported.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Health Care Sciences & Services
Guelbala Guloren, Yahya Dogan, Serap Ozgul, Ceren Gursen, Gamze Nalan Cinar, Funda Ipekten, Turkan Akbayrak
Summary: This study investigated the acute effects of daily remedial exercises with and without compression bandaging on the severity of breast-cancer-related lymphedema (BCRL). The results showed that exercise with compression significantly reduced lymphedema and symptoms compared to baseline, while exercise without compression did not have a significant impact.
Article
Medicine, Research & Experimental
Cristina Roldan-Jimenez
Summary: In recent decades, research has led to a paradigm shift in the approach to physical activity and exercise prescription in breast cancer survivors. Clinical guidelines now recommend resistance exercise (RE) instead of bedrest and avoiding strenuous activity in the upper limb. Studies have shown that RE in the upper extremities can have a preventive effect on breast cancer-related lymphedema (BCRL), particularly through the analysis of variables related to RE programs on lymphatic response and volumetry. However, there is still limited understanding of how inflammation and acute responses affect BCRL prevention and other physiological mechanisms.
MEDICAL HYPOTHESES
(2023)
Article
Oncology
A. J. Salacinski, E. J. Doyle, R. Damon, R. A. Acevedo, C. E. Broeder
Summary: The study found that a 12-week water aerobics program did not lead to changes in body composition or increase the risk of lymphedema in breast cancer survivors.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Oncology
Vesile Yildiz Kabak, Ceren Gursen, Ayca Aytar, Turkan Akbayrak, Tulin Duger
Summary: The study found that female patients with BCRL have lower physical activity levels compared to healthy controls, but a higher percentage of BCRL patients engage in regular exercise. The most common exercise barriers were fatigue, other responsibilities, and weather-related factors. Most participants preferred supervised, structured, combined-type, and moderate intensity exercise programs, and preferred to be informed by a physiotherapist at the time of cancer diagnosis.
SUPPORTIVE CARE IN CANCER
(2021)
Review
Nursing
Ling Wang, Yue Xian Shi, Ting Ting Wang, Ke Xin Chen, Shao Mei Shang
Summary: This systematic review provides evidence-based recommendations for resistance training in breast cancer-related lymphoedema (BCRL) and offers guidance for clinicians. Current guidelines and consensus documents need to be updated in terms of topics such as effectiveness of resistance training and resistance training outcome index.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Oncology
Mingfang Li, Wanbing Huang, Xiaomin Zhang, Jing Chen, Xia Luo, Yue Zhang, Chenxia Xiong, Jun Yan
Summary: This study aimed to investigate illness perceptions of breast cancer-related lymphedema and adherence to risk management behaviours in postoperative breast cancer survivors in China. The results indicated the importance of illness perceptions for adherence to risk management behaviours.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2022)
Article
Oncology
Sacha A. Roberts, Tessa C. Gillespie, Amy M. Shui, Cheryl L. Brunelle, Kayla M. Daniell, Joseph J. Locascio, George E. Naoum, Alphonse G. Taghian
Summary: This study aimed to determine the relationship between postoperative weight change and breast cancer-related lymphedema. The findings suggest that weight loss alone may not decrease the risk of developing BCRL.
Article
Sport Sciences
Sandra Christine Hayes, Ben Singh, Hildegard Reul-Hirche, Kira Bloomquist, Karin Johansson, Charlotta Jonsson, Melanie Louise Plinsinga
Summary: Exercise has positive effects on the prevention and treatment of cancer-related lymphedema (CRL), improving symptoms and health outcomes. A combination of aerobic and resistance exercise is recommended, and exercise should be guided by symptom response.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Oncology
H. Winters, H. J. P. Tielemans, S. Hummelink, N. J. Slater, D. J. O. Ulrich
Summary: In this study, it was found that vascularized lymph node transfer in combination with DIEP flap breast reconstruction can significantly improve lymphedema-related quality of life. Even without a decrease in volume difference, it can reduce the usage of compression garments and the need for physiotherapy.
Article
Oncology
Yawei Lin, Chao Wu, Chunyan He, Jiaran Yan, Yi Chen, Li Gao, Rongrong Liu, Baohua Cao
Summary: The study aimed to compare the effects of three exercise programs on lymphedema, pain, and quality of life in breast cancer patients, as well as explore the impact of intensive follow-up on the outcomes. The results showed that JME + PRE had the best effect on improving quality of life and preventing lymphedema, while JME + AE had the best effect in relieving pain. Furthermore, long-term and planned monitoring and follow-up were also found to be important.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Medicine, General & Internal
Hayoung Byun, Yunjeong Jang, Ju-Yeon Kim, Jae-Myung Kim, Chang Han Lee
Summary: This study compares the incidence and severity of shoulder dysfunction and lymphedema in two groups of patients undergoing unilateral breast cancer surgery. The group that received preoperative education showed less limitation in shoulder abduction and forward flexion at 6 months post-surgery. Furthermore, pain and disability scores improved significantly at 1 month post-surgery and gradually decreased over time.
Article
Pharmacology & Pharmacy
Stav Brown, Joseph H. Dayan, Michelle Coriddi, Leslie McGrath, Raghu P. Kataru, Babak J. Mehrara
Summary: This retrospective study analyzed the efficacy of using doxycycline to treat breast cancer-related lymphedema. The results showed no significant improvements in limb volume or L-Dex scores, but patients reported significant improvements in quality of life measures. This suggests that doxycycline may have a role in improving quality of life for patients with breast cancer-related lymphedema, although further larger studies are needed.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Oncology
Jia-Xin Li, Jie Gao, Jiang-Yan Song, Hui-Ping Li, Wen-Juan Yang, Dong-Tong Tong, Yang Zou
Summary: This study compared the effects of compression therapy and routine nursing in the treatment of breast cancer-related lymphedema. The results showed that compression therapy can reduce the morbidity of lymphedema and improve limb movement, but its effect on limb volume needs further exploration.
Review
Gastroenterology & Hepatology
Kara DiJoseph, Audrey Thorp, Alex Harrington, Kathryn H. Schmitz, Vernon M. Chinchilli, Jonathan G. Stine
Summary: This meta-analysis found that higher levels of physical activity are associated with a reduced risk of hepatocellular carcinoma (HCC). Vigorous physical activity showed an even stronger association with lower HCC risk. These findings support the use of regular physical activity as an effective preventive measure against HCC.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Editorial Material
Oncology
Michael E. Roth, Susan K. Parsons, Patricia A. Ganz, Lynne Wagner, Pamela S. Hinds, Sarah Alexander, Kristin Bingen, Sharon L. Bober, Julienne Brackett, David Cella, N. Lynn Henry, Daniel J. Indelicato, Rebecca H. Johnson, Tamara P. Miller, Shoshana M. Rosenberg, Kathryn H. Schmitz, Gita Thanarajasingam, Bryce B. Reeve, John M. Salsman
Summary: Disparities in care, treatment-related toxicity, and health-related quality of life for adolescents and young adults with cancer are often disregarded due to limited collection of patient-reported outcomes in cancer clinical trials. Standardizing the assessment of HRQoL and treatment toxicity in AYA CCTs is crucial for improving patient outcomes. The National Cancer Institute's Clinical Trials Network AYA PRO Task Force has identified key considerations and selected appropriate measures to address this issue.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Oncology
Marc A. Emerson, Bryce B. Reeve, Melissa B. Gilkey, Shekinah N. C. Elmore, Sandi Hayes, Cathy J. Bradley, Melissa A. Troester
Summary: The employment status of breast cancer survivors has a significant impact on their well-being, with variations observed among different races and age groups.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Gastroenterology & Hepatology
Jessica Dahmus, Breianna Hummer, Gloriany Rivas, Kathryn Schmitz, Stephen H. Caldwell, Curtis K. Argo, Ian Schreibman, Jonathan G. Stine
Summary: Cardiorespiratory fitness is independently associated with liver fibrosis in patients with NASH, and advanced fibrosis is predictive of lower fitness levels. Further research is needed to explore exercise training as a potential intervention to improve fitness and reduce morbidity and mortality in NASH patients.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Endocrinology & Metabolism
Justin C. Brown, Jennifer A. Ligibel, Tracy E. Crane, Despina Kontos, Shengping Yang, Emily F. Conant, Julie A. Mack, Rexford S. Ahima, Kathryn H. Schmitz
Summary: This study confirms that obesity and metabolic abnormalities are associated with background parenchymal enhancement (BPE) on dynamic contrast-enhanced magnetic resonance imaging. Through imaging and metabolic parameter analysis of 59 premenopausal women at high risk of breast cancer, it was found that BMI, body fat mass, insulin resistance, and leptin were positively correlated with BPE, while adiponectin was negatively correlated with BPE.
Article
Medicine, General & Internal
Melanie Potiaumpai, Kathryn H. Schmitz, Shin Mineishi, Seema Naik, Baldeep Wirk, Kevin Rakszawski, W. Christopher Ehmann, David Claxton, Myles Nickolich, Babette S. Zemel, Hong Zheng
Summary: This study aims to investigate the feasibility, acceptability and safety of a resistance training exercise programme in patients with haematological malignancies prior to haematopoietic stem cell transplant (HSCT). The study will compare the differences in physical function, body composition, bone mineral density and patient-reported outcomes between the exercise group and usual care control group. The results of the study will be disseminated through scientific publication and presentation at exercise-related and oncology-related scientific meetings.
Article
Rehabilitation
Carolina X. Sandler, Gabrielle C. Gildea, Rosalind R. Spence, Tamara L. Jones, Paul Eliadis, David Walker, Amanda Donaghue, Catherine Bettington, Jacqui Keller, Deb Pickersgill, Molly Shevill, Vivien Biggs, Beth Morrison, Fiona Jonker, Matthew Foote, John Bashford, Sandra C. Hayes
Summary: This study aimed to assess the safety, feasibility, and potential effect of an 18-week exercise intervention for adults with primary brain cancer. The results showed that the exercise intervention was safe and beneficial to the quality of life and functional outcomes for participants.
DISABILITY AND REHABILITATION
(2023)
Letter
Medicine, General & Internal
Sandra C. Hayes, Dimitrios Vagenas, Monika Janda
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Review
Sport Sciences
Melanie Louise Plinsinga, Ben Singh, Grace Laura Rose, Briana Clifford, Tom George Bailey, Rosalind Renee Spence, Jemma Turner, Michel Willem Coppieters, Alexandra Leigh McCarthy, Sandra Christine Hayes
Summary: This systematic review evaluated the effect of exercise on cancer-related pain in all cancers and found that exercise has a pain-relieving effect. However, there is a lack of research on factors such as exercise mode, degree of supervision, intervention duration and timing, pain types, measurement tool, and cancer type, which need further investigation.
Review
Oncology
Grace Laura Rose, Elizabeth Mary Stewart, Briana Kristine Clifford, Tom George Bailey, Alexandra Jane Rush, Claudia Rose Abbott, Sandra Christine Hayes, Andreas Obermair, Alexandra Leigh McCarthy
Summary: This study systematically reviewed the efficacy of exercise intervention for women during/following treatment for gynaecological cancer. The results showed that exercise intervention can improve aerobic capacity, muscular strength, and agility, but the effects on quality of life, body composition, balance, and flexibility were inconsistent.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Melanie Potiaumpai, Erica A. Schleicher, Ming Wang, Kristin L. Campbell, Kathleen Sturgeon, Kathryn H. Schmitz
Summary: Exercise can improve chemotherapy completion rate by reducing toxicities. Patients with breast cancer had higher completion rate compared with gastrointestinal cancer and pancreatic cancer. Every 2.72 unit increase in exercise adherence led to a 7% decrease in chemotherapy completion rate for GI patients.
Article
Health Care Sciences & Services
Susan Veldheer, Maxfield Whitehead-Zimmers, Candace Bordner, Benjamin Watt, E. Conroy, Kathryn H. Schmitz, Christopher Sciamanna
Summary: This study aimed to gather participant insights on intervention components and topics of interest for a digitally delivered gardening-focused multiple health behavior change intervention. A web-based survey revealed high interest in gardening programming, with a preference for brief videos and suggestions for content covering various aspects of gardening activities.
JMIR FORMATIVE RESEARCH
(2023)
Review
Public, Environmental & Occupational Health
Yufan Wang, Alexandra L. McCarthy, Sandra C. Hayes, Louisa G. Gordon, Vivian Chiu, Tom G. Bailey, Elizabeth Stewart, Haitham Tuffaha
Summary: This systematic review explores the cost-effectiveness of exercise interventions following cancer and found that exercise interventions are cost-effective for various cancer types despite heterogeneity in exercise delivery and economic evaluation methods. Decision-analytic modelling is recommended to account for the long-term benefits of exercise in cancer care.
PREVENTIVE MEDICINE
(2023)
Article
Oncology
Tamara L. Jones, Lara Edbrooke, Jonathan C. Rawstorn, Sandra C. Hayes, Ralph Maddison, Linda Denehy, Camille E. Short
Summary: The purpose of this analysis was to explore the associations between exercise behavior and three behavioral constructs from different theories among breast cancer survivors. The results showed that identified motivation and habits were significantly associated with total activity, while identified motivation and coping self-efficacy were significantly associated with resistance training. The findings suggest that incorporating strategies that support identified motivation, habits, and coping self-efficacy could promote increased exercise behavior among breast cancer populations.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Clinical Neurology
Michelle D. Smith, Joanne Manning, Mandy Nielsen, Sandra C. Hayes, Melanie L. Plinsinga, Michel W. Coppieters
Summary: This qualitative study aimed to explore the experiences of women with persistent pain following breast cancer treatment. The study found that women experienced various types and degrees of persistent pain which they believed were related to their breast cancer treatment. They felt the lack of information and advice about the possibility of experiencing persistent pain before and after treatment hindered coping. The findings highlight the importance of empathetic supportive care, access to relevant information, multidisciplinary care teams, and consumer support.
FRONTIERS IN PAIN RESEARCH
(2023)
