Review
Biochemistry & Molecular Biology
Jeanne Rakotopare, Franck Toledo, Alfonso Baldi
Summary: Studies on both animal models and humans have revealed that mutations affecting p53 activity can lead to features of certain bone marrow failure syndromes, including dyskeratosis congenita, Diamond-Blackfan anemia, and Fanconi anemia. p53 regulates multiple genes related to these syndromes, forming a positive feedback loop.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Yana Irawati, Haryoto Kusnoputranto, Umar Fahmi Achmadi, Ahmad Safrudin, Alfred Sitorus, Rifqi Risandi, Suradi Wangsamuda, Puji Budi Setia Asih, Din Syafruddin
Summary: The present study investigated the blood lead levels and evidence of lead toxicity among children living in an ULAB recycling site in Bogor Regency, Indonesia. The results showed that a majority of the children had elevated blood lead levels, as well as a significant proportion with underweight, stunting, and anemia. The study also revealed associations between blood lead levels and BMI, anemia, and basophilic stippling.
Article
Obstetrics & Gynecology
Ricardo Ataide, Katherine Fielding, Sant-Rayn Pasricha, Cavan Bennett
Summary: Anemia affects 36% of pregnant women worldwide, with around 40% of cases being due to iron deficiency. Iron deficiency has negative impacts on placental development and iron uptake, fetal development and immunity, as well as maternal and infant susceptibility to infection.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Multidisciplinary Sciences
Patrick J. Lenehan, Eshwan Ramudu, A. J. Venkatakrishnan, Gabriela Berner, Reid McMurry, John C. O'Horo, Andrew D. Badley, William Morice, John Halamka, Venky Soundararajan
Summary: A retrospective study compared laboratory test measurements in rehospitalized COVID-19 patients versus those not rehospitalized after viral clearance, finding that rehospitalized patients had lower hemoglobin levels and were more likely to have moderate or severe anemia. These findings suggest that anemia-related lab tests should be considered in risk assessment for COVID-19 patients.
Article
Multidisciplinary Sciences
Meltem Kilercik, Yasemin Ucal, Muhittin Serdar, Mustafa Serteser, Aysel Ozpinar, Florian J. Schweigert
Summary: ZnPP may be an important indicator of anemia in COVID-19 patients, and the ZnPP/L ratio may serve as a valid prognostic marker for the severity of the disease.
Article
Public, Environmental & Occupational Health
Kyuhyoung Jeong, Jiyeon Yoon, Heeran J. J. Cho, Sunghee Kim, Jihyun Jang
Summary: This study quantitatively examined the changes in the fertility rate of Korean local governments and the policy factors affecting the fertility rate. The results showed that the declining trend of fertility rate is increasing over time, and the number of in-kind policies has a significant effect on the initial value of fertility rate.
Article
Infectious Diseases
Tariro L. Mduluza-Jokonya, Arthur Vengesai, Herald Midzi, Maritha Kasambala, Luxwell Jokonya, Thajasvarie Naicker, Takafira Mduluza, Michael H. Hsieh, Gabriel Rinaldi, Michael H. Hsieh, Gabriel Rinaldi, Michael H. Hsieh, Gabriel Rinaldi, Michael H. Hsieh, Gabriel Rinaldi
Summary: This study analyzed the clinical signs and symptoms associated with early Schistosoma haematobium infection in pre-school age children. The prodromal signs and symptoms identified pave the way for early intervention and management, reducing the harm of late diagnosis common in endemic populations. The developed diagnostic algorithm showed high sensitivity, specificity, positive predictive value, and negative predictive value, indicating its potential utility in identifying early S. haematobium infection cases in resource-limited settings.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Review
Surgery
Anais Delgove, Olivier Camuzard, Manuela Perez, Marc Braun, Pierre Journeau, Gilles Dautel
Summary: This study reviewed five different incision sets for index pollicization in thumb aplasia, providing a standardized and reliable model for research and comparison of these incisions. The model can be used for educational purposes and to optimize surgical techniques.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Agriculture, Dairy & Animal Science
E. Rojas Canadas, M. M. Herlihy, J. Kenneally, F. Kearney, J. Furlong, P. Lonergan, S. T. Butler
Summary: This study aimed to evaluate the associations between plasma progesterone concentrations after first AI in post-partum dairy cows and their phenotypes, cow factors, and genetic traits. The research found that cows with superior genetic merit for fertility traits, favorable postpartum fertility phenotypes, and better metabolic status at AI were more likely to have greater plasma progesterone concentrations and higher odds of successful pregnancy establishment.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Immunology
Joao Neves, Carolina Barroso, Pedro Carvalho, Magda Nunes, Jose F. M. Goncalves, Pedro N. S. Rodrigues
Summary: Erythroferrone is a red blood cell regulator produced in mammalian bone marrow and extramedullary sites. This study investigated its function in European sea bass and found that it responds to experimental anemia by increasing expression and suppressing hepcidin production, similar to mammals. However, during bacterial infection, Erythroferrone is downregulated while hepcidin levels increase.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Immunology
Yuanfeng Zhang, Xin Chen, Donglin Yang, Aiming Pang, Rongli Zhang, Qiaoling Ma, Weihua Zhai, Yi He, Jialin Wei, Erlie Jiang, Mingzhe Han, Sizhou Feng
Summary: This study conducted a retrospective cohort analysis on patients with severe aplastic anemia (SAA) who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) to compare their survival between those with infection and those without infection. The study found that patients with infection before transplantation had inferior survival compared to those without infection, highlighting the importance of prophylaxis and complete control of infectious complications before transplantation among SAA patients.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Fergus Hamilton, Ruth Mitchell, Haroon Ahmed, Peter Ghazal, Nicholas J. Timpson
Summary: Iron deficiency is associated with morbidity, but iron supplementation may increase the risk of serious infection. This study used genetic variants as instrumental variables to analyze the relationship between iron biomarkers and sepsis risk. The results showed that higher levels of iron biomarkers increased the odds of sepsis, especially in individuals with iron deficiency and/or anemia. These findings highlight the importance of caution in iron supplementation and the role of iron homeostasis in severe infection.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Adeel Rahat, Lubna Kamani
Summary: The study revealed an association between H. Pylori infection and iron deficiency anemia, with 37.5% of the patients in the study population experiencing iron deficiency anemia.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Orthopedics
Friederike Schoemig, Justus Buerger, Zhouyang Hu, Axel Pruss, Edda Klotz, Matthias Pumberger, Christian Hipfl
Summary: This study analyzed the risk factors for postoperative spinal implant infection and found that the intraoperative Hb-trend is a predictor for the development of PSII. Further investigation into strategies to reduce intraoperative blood loss in spine surgery is needed to prevent such infections.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Review
Agriculture, Multidisciplinary
Pietro Magnabosco, Antonio Masi, Ravi Shukla, Vipul Bansal, Paolo Carletti
Summary: This review combines nanotechnology and biostimulant technology to highlight the potential role of nanotechnologies in advancing the impact of plant biostimulants for sustainable production of high-quality food. By integrating these two fields, a promising sustainable solution to food insecurity can be achieved for the near future.
CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE
(2023)