Chitinase 3–like-1 Regulates Both Visceral Fat Accumulation and Asthma-like Th2 Inflammation

The influence of obesity on inflammation and clinical symptoms in asthma

(2013) M Gruchała-Niedoszytko et al.   Advances in Medical Sciences

Elevated Sputum Interleukin-5 and Submucosal Eosinophilia in Obese Individuals with Severe Asthma

(2013) Dhananjay Desai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Obesity and asthma: location, location, location

(2013) Stephanie A. Shore   EUROPEAN RESPIRATORY JOURNAL

Interaction of Metabolic Syndrome with Asthma in Postmenopausal Women: Role of Adipokines

(2013) Murat Aydin et al.   INFLAMMATION

Eosinophils in the Spotlight: Finding the link between obesity and asthma

(2013) Clare M Lloyd et al.   NATURE MEDICINE

Obesity and asthma: A coincidence or a causal relationship? A systematic review

(2013) Zarqa Ali et al.   RESPIRATORY MEDICINE

Obesity increases eosinophil activity in asthmatic children and adolescents

(2013) Milena Baptistella Grotta et al.   BMC Pulmonary Medicine

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

(2013) Chuan Hua He et al.   Cell Reports

Involvement of the MAPK and PI3K pathways in chitinase 3-like 1-regulated hyperoxia-induced airway epithelial cell death

(2012) Mi Na Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses

(2012) Charles S. Dela Cruz et al.   Cell Host & Microbe

General and abdominal obesity and incident asthma in adults: the HUNT study

(2012) Ben Brumpton et al.   EUROPEAN RESPIRATORY JOURNAL

Two Closely Related Human Members of Chitinase-like Family, CHI3L1 and CHI3L2, Activate ERK1/2 in 293 and U373 Cells but Have the Different Influence on Cell Proliferation

(2012) Pavlo O. Areshkov et al.   International Journal of Biological Sciences

Tipping the scales early: probing the long-term effects of obesity

(2012) Chen Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

(2011) Chun Geun Lee et al.   Annual Review of Physiology

Carbohydrate-binding motif in chitinase 3-like 1 (CHI3L1/YKL-40) specifically activates Akt signaling pathway in colonic epithelial cells

(2011) Chun-Chuan Chen et al.   CLINICAL IMMUNOLOGY

SirT1 Regulates Adipose Tissue Inflammation

(2011) M. P. Gillum et al.   DIABETES

Sirtuin 1 Promotes Th2 Responses and Airway Allergy by Repressing Peroxisome Proliferator-Activated Receptor-  Activity in Dendritic Cells

(2011) A. Legutko et al.   JOURNAL OF IMMUNOLOGY

Asthma and obesity: A known association but unknown mechanism

(2011) CLAUDE S. FARAH et al.   RESPIROLOGY

The Chitinase-like Proteins Breast Regression Protein-39 and YKL-40 Regulate Hyperoxia-induced Acute Lung Injury

(2010) Myung Hyun Sohn et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dynamic, M2-Like Remodeling Phenotypes of CD11c+ Adipose Tissue Macrophages During High-Fat Diet-Induced Obesity in Mice

(2010) M. E. Shaul et al.   DIABETES

Lean mass predicts asthma better than fat mass among females

(2010) A. Sood et al.   EUROPEAN RESPIRATORY JOURNAL

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Lung Function Impairment and Metabolic Syndrome

(2009) Nathalie Leone et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PPAR γ is highly expressed in F4/80hi adipose tissue macrophages and dampens adipose-tissue inflammation

(2009) Josep Bassaganya-Riera et al.   CELLULAR IMMUNOLOGY

SIRT1 Genetic Variation Is Related to BMI and Risk of Obesity

(2009) M.Carola Zillikens et al.   DIABETES

Involvement of sirtuin 1 in airway inflammation and hyperresponsiveness of allergic airway disease

(2009) So Ri Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

(2009) Chun Geun Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Obesity, waist size and prevalence of current asthma in the California Teachers Study cohort

(2009) J Von Behren et al.   THORAX

Biomarkers for lysosomal storage disorders: identification and application as exemplified by chitotriosidase in Gaucher disease

(2008) Johannes M Aerts et al.   ACTA PAEDIATRICA

Chitinase 3-Like-1 (CHI3L1): A Putative Disease Marker at the Interface of Proteomics and Glycomics

(2008) Frederick D. Coffman   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES