Article
Medicine, General & Internal
Laura Berthommier, Lucie Planche, Guillaume Ducarme
Summary: This study retrospectively analyzed the mode of delivery and its impact on severe maternal and neonatal morbidity in 362 women with term singleton breech presentation. The results showed that cervical ripening did not increase the incidence of severe maternal and neonatal morbidity in appropriately selected candidates.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Pediatrics
Jessica Mercier, Letizia Gremillet, Antoine Netter, Cecile Chau, Catherine Gire, Barthelemy Tosello
Summary: This study investigated the neurological outcomes at two years of age for newborns from monochorionic biamniotic twin pregnancies complicated by selective intrauterine growth restriction (sIUGR). The results showed that these newborns had similar overall neurological development to newborns from intrauterine growth restriction (IUGR) pregnancies. Notably, the IUGR group showed the most moderate impairment in fine motor skills, likely due to antenatal brain development issues caused by placenta insufficiency and chronic hypoxia.
Article
Obstetrics & Gynecology
Beth L. Pineles, Hector Mendez-Figueroa, Suneet P. Chauhan
Summary: This study aimed to compare the adverse outcomes of neonates and mothers with detected and undetected small for gestational age. The results showed that although undetected small for gestational age had some complications, antenatal detection of small for gestational age was not associated with improved neonatal adverse outcomes.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2022)
Article
Pediatrics
Dinushan C. Kaluarachchi, Victoria B. Nicksic, David B. Allen, Jens C. Eickhoff, Mei W. Baker, Pamela J. Kling
Summary: The study aimed to test the hypothesis that term-born small for gestational age (SGA) neonates have elevated thyroid-stimulating hormone (TSH) concentrations and an increased incidence of congenital hypothyroidism compared with non-SGA term neonates. Results showed that while TSH concentration and incidence of congenital hypothyroidism were significantly higher in the SGA group, only TSH concentration remained significant when adjusted for potential confounding variables.
JOURNAL OF PEDIATRICS
(2021)
Article
Pediatrics
Maria Sonsoles Galan Arevalo, Ignacio Mahillo-Fernandez, Miguel Saenz De Pipaon, Luis Mariano Esteban, Diego Hernandez Martin, Juan Rodriguez Delgado, Jose Carlos Estevez Munoz, Mercedes Andeyro-Garcia, Roi Pineiro Perez, Ricardo Saviron-Cornudella
Summary: Newborns with fetal growth deceleration (FGD) but appropriate-for-gestational-age (AGA) weight experience catch-up growth, especially in weight and BMI, in the first year of life.
PEDIATRIC RESEARCH
(2023)
Article
Nutrition & Dietetics
Marta Meneghelli, Andrea Peruzzo, Elena Priante, Maria Elena Cavicchiolo, Luca Bonadies, Laura Moschino, Francesca De Terlizzi, Giovanna Verlato
Summary: There are differences in bone health between IUGR and non-IUGR preterm infants, and special nutritional care is needed for IUGR newborns to promote bone development.
Article
Obstetrics & Gynecology
Jesrine Hong, Kylie Crawford, Anthony O. Odibo, Sailesh Kumar
Summary: This study evaluated the risks of stillbirth, neonatal mortality, and severe neonatal morbidity in relation to the timing of birth between 37 and 40 weeks of gestation. The results suggest that the optimal time of birth varies depending on the infant's birthweight centile, with 37 to 37+6 weeks being optimal for infants below the third centile, 38 to 38+6 weeks for infants between the third and tenth centiles and above the ninetieth centile, and 39 weeks for infants in other birthweight centiles.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Medicine, General & Internal
Jae Kyoon Hwang, Ha-Na Kang, Ja-Hye Ahn, Hyun Ju Lee, Hyun-Kyung Park, Chang-Ryul Kim
Summary: This study evaluated the impact of intrauterine stress on extremely premature infants in terms of intrauterine growth restriction. The results showed that extremely premature infants with mildly-low ponderal index had better neonatal outcomes, with lower mortality and morbidity rates compared to infants with severely-low or high ponderal index.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2022)
Article
Obstetrics & Gynecology
Han-Yang Chen, Suneet P. Chauhan
Summary: The study shows that nondiabetic women who labor with macrosomic newborns have a significantly higher risk of adverse outcomes compared to nonmacrosomic newborns.
AMERICAN JOURNAL OF PERINATOLOGY
(2021)
Article
Acoustics
M. F. Mino, M. Pauta, E. Meler, I. Matas, E. Mazarico, A. Camacho, M. Segura, F. Figueras, A. Borrell
Summary: This study aims to determine the frequency of genetic syndromes and childhood neurodevelopmental impairment in non-malformed term infants with severely low birth weight and no evidence of placental insufficiency. The findings suggest that these infants have a relatively high rate of genetic syndromes and neurodevelopmental impairment, despite the absence of clinical or Doppler signs of placental insufficiency.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Medicine, General & Internal
Rafael R. Domingues, Adam D. Beard, Meghan K. Connelly, Milo C. Wiltbank, Laura L. Hernandez
Summary: This study investigated the effects of fluoxetine treatment during the last month of gestation on pregnancy complications, placental, and neonatal health. The results showed that fluoxetine treatment reduced placental growth, resulting in shortened gestation, decreased birthweight, and neonatal acidemia.
FRONTIERS IN MEDICINE
(2022)
Article
Acoustics
Wesley Lee, Lauren M. Mack, Roxanna Miremadi, Betul Yilmaz Furtun, Haleh Sangi-Haghpeykar, Greggory R. DeVore
Summary: The objective of this study was to investigate cardiac size, shape, and ventricular contractility in fetuses with estimated fetal weight (EFW) <10th centile at sea level. The results showed that fetuses with EFW <10th centile at sea level often had enlarged and globular-shaped hearts, with increased ventricular contractility. In comparison, fetuses at higher altitude had similar heart shape but a higher proportion with decreased ventricular contractility.
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Kaiwen Bai, Luyi Jiang, Qiming Li, Jingfei Zhang, Lili Zhang, Tian Wang
Summary: This study aimed to understand the mechanism underlying skeletal muscle dysfunction caused by intrauterine growth restriction (IUGR) and found that adding DMG-Na to sow milk during the suckling period can improve skeletal muscle performance in newborns.
Review
Medicine, General & Internal
Steven J. Korzeniewski, Elizabeth Sutton, Carlos Escudero, James M. Roberts
Summary: Preeclampsia is a maternal syndrome characterized by new onset hypertension after 20 weeks of gestation that may have long-term adverse effects on both mothers and their children, including cardiovascular, metabolic, cerebral, and cognitive complications.
FRONTIERS IN MEDICINE
(2022)
Article
Obstetrics & Gynecology
Anjali Walia, Victoria K. Berger, Juan M. Gonzalez, Nasim C. Sobhani
Summary: Clinicians often choose cesarean delivery instead of trial of labor in cases of preterm severe preeclampsia due to concerns about placental dysfunction. However, this study found that the presence of fetal growth restriction does not affect the mode of delivery or neonatal outcomes in pregnancies undergoing induction of labor at or before 34 weeks. Therefore, induction of labor can be considered a reasonable approach for patients with concurrent preterm severe preeclampsia and fetal growth restriction.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Editorial Material
Obstetrics & Gynecology
J. G. Thornton
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Letter
Obstetrics & Gynecology
John Allotey, Susan Bewley, Louise C. Kenny, Laura Ann Magee, Rachel K. Morris, Keelin O'Donoghue, Ash Paul, Maarten van Smeden, Shakila Thangaratinam, James G. Thornton, Peter Von Dadelszen, Javier Zamora
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Medicine, General & Internal
Lise Qvirin Krogh, Sidsel Boie, Tine Brink Henriksen, Jim Thornton, Jens Fuglsang, Julie Glavind
Summary: Obesity is associated with pregnancy complications and increased risk of caesarean section. This study aims to compare labour induction at gestational week 39 with expectant management in women with body mass index >= 30 kg/m(2) regarding the risk of caesarean section.
Article
Medicine, General & Internal
Bronacha Mylrea-Foley, Jim G. Thornton, Edward Mullins, Neil Marlow, Kurt Hecher, Christina Ammari, Birgit Arabin, Astrid Berger, Eva Bergman, Amarnath Bhide, Caterina Bilardo, Julia Binder, Andrew Breeze, Jana Brodszki, Pavel Calda, Rebecca Cannings-John, Andrej Cerny, Elena Cesari, Irene Cetin, Andrea Dall'Asta, Anke Diemert, Cathrine Ebbing, Torbjorn Eggebo, Ilaria Fantasia, Enrico Ferrazzi, Tiziana Frusca, Tullio Ghi, Jenny Goodier, Patrick Greimel, Wilfried Gyselaers, Wassim Hassan, Constantin Von Kaisenberg, Alexey Kholin, Philipp Klaritsch, Ladislav Krofta, Peter Lindgren, Silvia Lobmaier, Karel Marsal, Giuseppe M. Maruotti, Federico Mecacci, Kirsti Myklestad, Raffaele Napolitano, Eva Ostermayer, Aris Papageorghiou, Claire Potter, Federico Prefumo, Luigi Raio, Jute Richter, Ragnar Kvie Sande, Dietmar Schlembach, Ekkehard Schleussner, Tamara Stampalija, Basky Thilaganathan, Julia Townson, Herbert Valensise, Gerard Ha Visser, Ling Wee, Hans Wolf, Christoph C. Lees
Summary: This study aims to determine the optimal timing of delivery for cases of fetal growth restriction between 32 weeks and 36 weeks 6 days of gestation, based on cerebral blood flow redistribution. The hypothesis is that delivery based on evidence of cerebral blood flow redistribution can reduce poor perinatal outcome, death, and short-term hypoxia-related morbidity, with no worsening of neurodevelopmental outcome at 2 years.
Article
Psychology, Clinical
Yvette M. G. A. Hendrix, Misha A. T. Sier, Melanie A. M. Baas, Maria G. van Pampus
Summary: This study explored therapists' beliefs and experiences regarding the treatment of PTSD during pregnancy. The majority of therapists reported treating PTSD during pregnancy and found the treatment to be effective, despite hearing concerns about its potential harm. Only a small percentage of therapists reported perceived adverse events associated with treatment. These findings suggest a positive view on the treatment of PTSD in pregnancy.
JOURNAL OF TRAUMATIC STRESS
(2022)
Article
Obstetrics & Gynecology
Sanne J. M. Zilver, Yvette M. G. A. Hendrix, Birit F. P. Broekman, Robert A. de Leeuw, Christianne J. M. de Groot, Maria G. van Pampus
Summary: Pregnant women during the COVID-19 pandemic had lower fear of childbirth compared to pregnant women before the pandemic, possibly due to increased information, more time to consume information, and better work-life balance with more people working at home during the pandemic.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2022)
Article
Cardiac & Cardiovascular Systems
Jiao Luo, Raymond Noordam, J. Wouter Jukema, Ko Willems van Dijk, Sara Hagg, Felix Grassmann, Saskia le Cessie, Diana van Heemst
Summary: This study investigates the associations between leukocyte mitochondrial DNA abundance and coronary artery disease (CAD) and heart failure (HF), and utilizes Mendelian randomization for causal inference. The findings suggest that lower leukocyte mitochondrial DNA abundance is causally associated with higher CAD risk, but not with heart failure.
CARDIOVASCULAR RESEARCH
(2023)
Article
Transplantation
Robin Lengton, Esmee M. van der Willik, Esther N. M. de Rooij, Yvette Meuleman, Saskia Le Cessie, Wieneke M. Michels, Marc Hemmelder, Friedo W. Dekker, Ellen K. Hoogeveen
Summary: This study investigated the association between residual estimated glomerular filtration rate (eGFR), dialysis adequacy, or serum phosphate level and chronic kidney disease-associated pruritus (CKD-aP) in incident dialysis patients. The results showed that higher residual eGFR and lower serum phosphate level, but not the dialysis dose, were related to a lower burden of CKD-aP in dialysis patients.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Public, Environmental & Occupational Health
Jungyeon Choi, Olaf M. Dekkers, Saskia le Cessie
Summary: Ill-defined research questions can cause problems in epidemiological studies where measurements are subject to fluctuations due to events like medication use. Failing to specify how medication use should be handled during analysis can lead to arbitrary decisions and a disconnect between the intended question and analysis, resulting in different or meaningless interpretations of effects. This study discusses the formulation of well-defined research questions when medication use is involved, distinguishing between scenarios where exposure or outcome is affected by medication use and addressing methodological considerations under each question.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2023)
Article
Mathematical & Computational Biology
Doranne Thomassen, Ewout Steyerberg, Saskia le Cessie
Summary: In clinical practice, it is crucial to determine the absolute risk reduction of treatment for individual patients. However, logistic regression in trials with binary outcomes provides estimates of treatment effects in terms of log odds differences. In this study, we propose a new Bayesian regression model for binary outcomes on the additive risk scale, allowing for direct estimation of treatment effects on the linear scale of clinical interest. Comparisons were made with a previously proposed additive risk model and backtransforming predictions from a logistic model. Results showed that modelling untransformed risk can yield significantly different treatment effect estimates, particularly for small sample sizes or extreme predicted risks close to 0% or 100%. Our proposed model proved to be more sensitive in detecting all information in the data in a network meta-analysis.
STATISTICS IN MEDICINE
(2023)
Article
Obstetrics & Gynecology
Melanie A. M. Baas, Claire A. I. Stramrood, Lea M. Dijksman, Joost W. Vanhommerig, Ad de Jongh, Marielle G. van Pampus
Summary: EMDR therapy is an effective treatment for pregnant women with fear of childbirth, as it does not have any adverse effects on pregnancy or the fetus.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Medical Laboratory Technology
Tirsa T. van Duijl, Esther N. M. de Rooij, Maxim M. Treep, Marte E. Koelemaij, Fred P. H. T. M. Romijn, Ellen K. Hoogeveen, L. Renee Ruhaak, Saskia le Cessie, Johan W. de Fijter, Christa M. Cobbaert
Summary: This study explored the potential of emerging and conventional urinary kidney injury biomarkers in different populations using LC-MS/MS analysis. The results showed that kidney injury biomarkers were increased in kidney transplant recipients with ischemia-reperfusion injury. NGAL and B2M showed the strongest response.
CLINICAL CHEMISTRY
(2023)
Letter
Obstetrics & Gynecology
Jim Thornton
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Health Care Sciences & Services
Leon G. Martens, Daan van Hamersveld, Saskia le Cessie, Ko Willems van Dijk, Diana van Heemst, Raymond Noordam
Summary: Low socioeconomic status (SES) is associated with increased cardiovascular risk factors and coronary artery disease (CAD) risk. This study found that SES can modify the association between classical cardiovascular risk factors and CAD in European-ancestry participants. Furthermore, the risk for CAD attributable to increased body mass index (BMI) is not the same across different SES groups.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Bart J. J. Velders, J. W. Taco Boltje, Michiel D. Vriesendorp, Robert J. M. Klautz, Saskia Le Cessie, Rolf H. H. Groenwold
Summary: This study systematically evaluated the quality of conduct and reporting of confounding adjustment methods in observational studies on cardiothoracic interventions. The findings showed insufficient reporting of these methods, making it difficult to assess the quality. Proper application of confounding adjustment methods is crucial for causal inference on optimal treatment strategies in clinical practice.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)