Article
Immunology
Jeanne Sibiude, Jerome Le Chenadec, Laurent Mandelbrot, Alexandre Hoctin, Catherine Dollfus, Albert Faye, Eida Bui, Emmanuelle Pannier, Jade Ghosn, Valerie Garrait, Veronique Avettand-Fenoel, Pierre Frange, Josiane Warszawski, Roland Tubiana
Summary: Antiretroviral therapy initiated before pregnancy and continued throughout pregnancy can significantly reduce perinatal transmission of HIV. Factors such as not breastfeeding, infant prophylaxis, and maternal viral suppression near delivery play important roles in preventing transmission.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Gilmar de Souza Osmundo Jr, Rafaela Alkmin da Costa, Rosa Maria Aveiro Ruocco, Rossana Pulcineli Vieira Francisco
Summary: This retrospective cohort study aimed to analyze the perinatal outcomes of Perinatally acquired HIV Infection (PHIV) in pregnant women. The study included singleton pregnancies in Women Living with HIV (WLH) between 2006 and 2019. The results showed that PHIV did not increase the risk of adverse perinatal outcomes. Rating: 9/10.
Article
Immunology
Salome Maswime, Caroline Pule, Zama Mtshali, Richard Chawana, Mushi Matjila
Summary: Africa has the highest number of pregnant women with HIV, which is associated with adverse perinatal outcomes. The use of antiretroviral therapy has helped reduce transmission and adverse fetal outcomes, but further research is needed to understand the placental mechanisms and fetal immune responses to maternal HIV infection.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Lingyun Hu, Jing Ning, Li'an Li, Yanping Lu, Yanqin You
Summary: Uterine artery spontaneous rupture is a rare but potentially life-threatening complication during pregnancy and puerperium. Early diagnosis and prompt surgical intervention are crucial in preventing serious consequences for both the mother and fetus.
Article
Obstetrics & Gynecology
M. E. Foeller, C. Nosrat, A. Krystosik, T. Noel, P. Gerardin, N. Cudjoe, V Mapp-Alexander, G. Mitchell, C. Macpherson, R. Waechter, A. D. LaBeaud
Summary: The study found that CHIKV infection during pregnancy may protect against long-term joint pain, without increasing the risk of pregnancy complications or neonatal health issues. Maternal infection just prior to delivery might increase the risk of mother-to-child transmission of CHIKV.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Review
Medicine, General & Internal
Clara Portwood, Harriet Sexton, Mary Kumarendran, Zoe Brandon, Shona Kirtley, Joris Hemelaar
Summary: This study evaluated the risk of adverse perinatal outcomes in pregnant women living with HIV (WLHIV) receiving antiretroviral therapy (ART) compared to ART-naive WLHIV and HIV-negative women. The findings showed that WLHIV receiving ART had a lower risk of preterm birth, low birth weight, and other adverse perinatal outcomes compared to ART-naive WLHIV. However, they still had a higher risk of these outcomes compared to HIV-negative women.
FRONTIERS IN MEDICINE
(2023)
Article
Multidisciplinary Sciences
Jorge Saz, Albert Dalmau-Bueno, Michael Meulbroek, Ferran Pujol, Josep Coll, Angel Herraiz-Tomey, Felix Perez, Giovanni Marazzi, Hector Taboada, Dante R. Culqui, Joan A. Cayla
Summary: The use of fourth-generation rapid diagnostic tests in identifying acute HIV infection is effective in early diagnosis and treatment, with regular repeat testing for those who test negative. The study showed a positivity rate of 3.32% among 27,298 rapid tests, with high viral loads detected in the p24 antigen group, initiating treatment promptly on the following working day.
Article
Multidisciplinary Sciences
Melanie Plazy, Adama Diallo, Thabile Hlabisa, Nonhlanhla Okesola, Collins Iwuji, Kobus Herbst, Sylvie Boyer, France Lert, Nuala McGrath, Deenan Pillay, Francois Dabis, Joseph Larmarange, Joanna Orne-Gliemann
Summary: This study reports on the implementation and effectiveness of a linkage-to-care intervention in rural South Africa, which involved tracking HIV-positive individuals through phone calls and home visits. The results showed that this intervention was effective in improving the linkage-to-care rate among patients.
Article
Immunology
Adam W. Bartlett, Tavitiya Sudjaritruk, Thahira J. Mohamed, Suvaporn Anugulruengkit, Nagalingeswaran Kumarasamy, Wanatpreeya Phongsamart, Penh Sun Ly, Khanh Huu Truong, Lam Van Nguyen, Viet Chau Do, Pradthana Ounchanum, Thanyawee Puthanakit, Kulkanya Chokephaibulkit, Pagakrong Lumbiganon, Nia Kurniati, Nik Khairulddin Nik Yusoff, Dewi Kumara Wati, Annette H. Sohn, Azar Kariminia
Summary: The study analyzed treatment failure among adolescents with perinatally acquired HIV infection in a regional cohort in Asia, identifying the rate of treatment failure events, subsequent management, and impact on survival rates. Results showed that subsequent cART switching after treatment failure can lead to improved immunologic and virologic outcomes, but treatment failure is associated with an increased cumulative incidence of death and loss to follow-up.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Qian Yang, Maria C. Magnus, Fanny Kilpi, Gillian Santorelli, Ana Goncalves Soares, Jane West, Per Magnus, John Wright, Siri Eldevik Haberg, Eleanor Sanderson, Deborah A. Lawlor, Kate Tilling, Maria Carolina Borges
Summary: Observational studies have shown that maternal sleep duration is associated with adverse pregnancy and perinatal outcomes. However, it is unclear whether there are nonlinear causal effects. This study used Mendelian randomization and multivariable regression to examine the nonlinear effects of sleep duration on various outcomes. The results suggest that shorter and longer sleep duration may increase the risks of stillbirth, perinatal depression, and low offspring birthweight.
Review
Medicine, General & Internal
Laura N. Broyles, Robert Luo, Debi Boeras, Lara Vojnov
Summary: This article summarizes the risk of sexual transmission of HIV from individuals with low-level viral loads and emphasizes its importance in public health. The review of 8 studies shows that the risk of HIV transmission is almost zero when viral loads are below 1000 copies per mL. These findings can help destigmatize HIV and promote adherence to antiretroviral therapy.
Article
Obstetrics & Gynecology
Nivashnee Naicker, Nonhlanhla Yende-Zuma, Ayesha B. M. Kharsany, Hlengiwe Shozi, Duduzile Nkosi, Anushka Naidoo, Nigel Garrett, Salim S. Abdool Karim
Summary: Pregnancy rates following HIV acquisition in South Africa are high, highlighting the importance of timely provision of antiretroviral therapy and contraception counseling for women recently diagnosed with HIV. The study also showed improvements in CD4 count and HIV viral load trajectories in pregnant women over time.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Review
Obstetrics & Gynecology
Laura Saint-Lary, Justine Benevent, Christine Damase-Michel, Christophe Vayssiere, Valeriane Leroy, Agnes Sommet
Summary: In this study, the researchers conducted a systematic review on the adverse perinatal outcomes associated with prenatal exposure to protease inhibitors (PI) based antiretroviral therapy (ART) compared with non-nucleoside reverse transcriptase inhibitors (NNRTI) based ART. The findings showed no significant association between prenatal exposure to PIs and most adverse perinatal outcomes, except for a significantly increased risk of very small for gestational age (VSGA).
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Immunology
Naima T. Joseph, Glen A. Satten, Rachel E. Williams, Lisa B. Haddad, Denise J. Jamieson, Anandi N. Sheth, Martina L. Badell
Summary: Pregnant women receiving combined INSTI and TAF therapy have an increased risk of excess gestational weight gain. Pregnant women receiving combined INSTI and TAF therapy have an increased risk of excess gestational weight gain, while the use of tenofovir disoproxil fumarate may have a protective effect, regardless of INSTI use.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Obstetrics & Gynecology
Xiang Han, Hongyan Du, Yinli Cao, Yan Zhang, Jingjing Zhang, Li Zhang, Zhankui Li, Yaling Xu, Hongxia Zou, Bo Sun
Summary: The study investigated the incidence and outcome of chorioamnionitis in a provincial perinatal center, finding that histological CA was associated with early-onset sepsis and perinatal comorbidities. Placental histological examination should be routinely performed in very preterm births for better assessment of perinatal and neonatal outcomes.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2021)
Article
Immunology
Martina L. Badell, Anandi N. Sheth, Florence Momplaisir, Lisa Rahangdale, JoNell Potter, Padmashree C. Woodham, Gweneth B. Lazenby, William R. Short, Scott E. Gillespie, Nevert Baldreldin, Emily S. Miller, Gregg Alleyne, Lunthita M. Duthely, Stephanie M. Allen, Judy Levison, Rana Chakraborty
OPEN FORUM INFECTIOUS DISEASES
(2019)
Article
Nursing
JoNell E. Potter, Lunthita M. Duthely, Nelly Diaz-Mendez, Lindsay Smith, Barbara J. Messick, Maria Echenique, Johnny Galli, Salih Yasin, Olga Villar-Loubet
JOURNAL OF MIDWIFERY & WOMENS HEALTH
(2019)
Article
Environmental Sciences
Daniel Samano, Shubhayu Saha, Taylor Corbin Kot, JoNell E. Potter, Lunthita M. Duthely
Summary: This study aimed to identify the association between extreme weather events and HIV-clinic attendance rates, highlighting the potential impact of climate change on healthcare utilization among vulnerable populations.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Lunthita M. Duthely, Alex P. Sanchez-Covarrubias, Megan R. Brown, Tanya E. Thomas, Emily K. Montgomerie, Sannisha Dale, Steven A. Safren, JoNell E. Potter
Summary: This study identified multiple interrelated barriers to adherence among ethnic minority women with HIV. Ethnic group-specific differences underscore the importance of implementing culturally-competent interventions. Participants suggested additional intervention features and endorsed the use of mCARES as a strategy to improve adherence to treatment and appointments, despite concerns about privacy and confidentiality.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Chemistry, Multidisciplinary
Anuj Shah, Isabella Lopez, Bapurao Surnar, Shrita Sarkar, Lunthita M. Duthely, Asha Pillai, Tina T. Salguero, Shanta Dhar
Summary: The article points out the unique challenges faced by women in STEM during the pandemic and provides recommendations for specific policies and practices. It emphasizes taking action to support women in academic institutions, journals, government/federal centers, university-level departments, and research groups to promote gender equality.
Article
Public, Environmental & Occupational Health
Hanni Stoklosa, Lujain Alhajji, Lindsey Finch, Sacha Williams, Jaya Prakash, Anna K. Sfakianaki, Lunthita M. Duthely, JoNell E. Potter
Summary: This study aims to explore the impact of child welfare involvement on trafficked birth mothers. The results show that participants engage in child welfare involvement for various reasons and provide recommendations for system improvement. Practical recommendations include mechanisms to support trafficked mothers, enhanced engagement of social workers and all providers, and improvement of social determinants of health and trauma-informed child welfare referrals.
MATERNAL AND CHILD HEALTH JOURNAL
(2022)
Article
Nursing
Emmanuela N. Ojukwu, Rosina Cianelli, Natalia Villegas Rodriguez, Karina Gattamorta, Giovanna De Oliveira, Lunthita Duthely
Summary: Guided by Mcleroy's socio-ecological model, this study explored the predictors and social determinants of HIV treatment engagement among Black post-partum women living with HIV. The results showed that maternal prenatal health significantly affected both immediate post-partum and ongoing primary care engagement at the intrapersonal level, while HIV disclosure and intimate partner violence/abuse significantly affected immediate post-partum engagement at the interpersonal level. Immediate post-partum disengagement was also a significant predictor for ongoing primary care disengagement.
JOURNAL OF ADVANCED NURSING
(2023)
Review
Infectious Diseases
Emily K. Montgomerie, Cassandra Michel, Alex P. Sanchez-Covarrubias, Lunthita M. Duthely
Summary: This study compared the endorsement of pandemic-related stress and support among participants attending an urban clinic in Southeastern Florida from January to May 2021. The results showed that long-term survivor women living with HIV (WLWH) had lower stress and higher support compared to their short-term survivor counterparts. These findings are important for understanding and addressing disparities within the WLWH population.
HIV AIDS-RESEARCH AND PALLIATIVE CARE
(2023)
Article
Obstetrics & Gynecology
Alex P. Sanchez-Covarrubias, Joshua Crane, Emily K. Montgomerie, JoNell E. Potter, Lunthita M. Duthely, Felicia Bahadue, Patricia P. Jeudin
Summary: Women living with HIV have an increased risk of HPV infection, precancers, and cervical cancers. This study found that HPV detection and AIDS status are significant factors predicting progression to cervical intraepithelial neoplasia among minority WLWH.
JOURNAL OF LOWER GENITAL TRACT DISEASE
(2022)
Article
Public, Environmental & Occupational Health
Lunthita M. Duthely, Alex P. Sanchez-Covarrubias, Varsha Prabhakar, Megan R. Brown, Tanya E. S. Thomas, Emily K. Montgomerie, JoNell E. Potter
Summary: The study found that English-speaking patients in a U.S. safety net clinic cohort exhibited the highest level of medical mistrust, while Creole-speaking patients showed lower levels of mistrust and suspicion of providers. Higher levels of mistrust were significantly associated with lower medication adherence.
Article
Public, Environmental & Occupational Health
Lydia A. Fein, Isabella Rosa Cunha, Adriana Wong, Matthew P. Schlumbrecht, Lunthita M. Duthely, JoNell E. Potter
Summary: This study found that in HIV/STI-rich areas, transgender people have low awareness of anal cancer and related screening tools, and a low perception of personal risk of anal cancer. High-risk factors include smoking, STI history, and inconsistent condom use. Therefore, there is a need to increase awareness of anal cancer, risk factors, and screening methods.
Review
Communication
Lunthita M. Duthely, Alex P. Sanchez-Covarrubias
FRONTIERS IN COMMUNICATION
(2020)
Article
Health Care Sciences & Services
Lunthita M. Duthely, Alex P. Sanchez-Covarrubias, Adhar B. Mohamed, JoNell E. Potter
JMIR RESEARCH PROTOCOLS
(2020)
Article
Public, Environmental & Occupational Health
Tiffany R. Glynn, Steven A. Safren, Adam W. Carrico, Noelle A. Mendez, Lunthita M. Duthely, Sannisha K. Dale, Deborah L. Jones, Daniel J. Feaster, Allan E. Rodriguez
Article
Health Policy & Services
Louise Underdahl, Terri Jones-Meineke, Lunthita M. Duthely
INTERNATIONAL JOURNAL OF HEALTHCARE MANAGEMENT
(2018)
