Article
Medicine, General & Internal
Hae-Ri Kim, Jae-Wan Jeon, Hong-Jin Bae, Jin-Ah Shin, Young-Rok Ham, Ki-Ryang Na, Kang-Wook Lee, Dae-Eun Choi, Yun-Kyong Hyon
Summary: Accurate dry weight estimation is crucial for hemodialysis patients. Bioimpedance spectroscopy is commonly used for this purpose, but often differs from clinical measurements. This study identified that fat mass significantly predicts the accuracy of dry weight estimation, with lower fat mass leading to underestimation and higher fat reserves leading to overestimation of dry weight.
Article
Biochemical Research Methods
Xiaoyi Guo, Wei Zhou, Bin Shi, Xiaohua Wang, Aiyan Du, Yijie Ding, Jijun Tang, Fei Guo
Summary: This study utilized a machine learning model to predict the dry weight of hemodialysis patients, revealing positive correlations between dry weight and BMI and HR, and negative correlations with age, sex, blood pressure, and dialysis time. The proposed model offers a viable alternative for dry weight estimation in clinical practice.
CURRENT BIOINFORMATICS
(2021)
Article
Urology & Nephrology
Kimio Watanabe, Yugo Ito, Takuya Fujimaru, Masahiko Nagahama, Fumika Taki, Masaaki Nakayama
Summary: This study examines the merits of performing bioimpedance analysis in addition to conventional evaluation methods for dry weight in chronic hemodialysis patients. The results suggest that patients with a ratio of extracellular water to total body water of more than 45% and hANP value of >= 50 pg/mL were overhydrated and had higher blood pressure and cardiothoracic ratio. Further study is needed to determine the impact of monitoring these parameters on patient outcomes, including survival and cardiovascular events.
CLINICAL AND EXPERIMENTAL NEPHROLOGY
(2022)
Article
Urology & Nephrology
Meredith McAdams, L. Parker Gregg, Rong Lu, Michael Concepcion, Swati Lederer, Jeff Penfield, Peter Noel Van Buren
Summary: This study found that post-HD ECV is more strongly associated with ambulatory blood pressure in hemodialysis patients than intradialytic TPRI changes or interdialytic ECV increases. Recognizing and managing chronic ECV overload are essential for improving ambulatory blood pressure in HD patients, especially for those with recurrent intradialytic hypertension.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Physiology
Usama Hussein, Monica Cimini, Garry J. Handelman, Jochen G. Raimann, Li Liu, Samer R. Abbas, Peter Kotanko, Nathan W. Levin, Fredric O. Finkelstein, Fansan Zhu
Summary: This study aimed to compare bioimpedance methods and clinical assessments for detecting fluid overload in patients with chronic kidney disease. The study found that bioimpedance methods were more sensitive in diagnosing fluid overload in these patients, while clinical assessments tended to underestimate the condition.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Editorial Material
Urology & Nephrology
Manfred Hecking, Magdalena Madero, Friedrich K. Port, Daniel Schneditz, Peter Wabel, Charles Chazot
Summary: The question of how much fluid should be removed at the beginning of each hemodialysis session has not been answered accurately. This article discusses the concept of probing-dry weight with the example of Tassin/France, where mortality outcomes were better in the past but have now become similar to the European average. Based on recent trials and meta-analyses, the article explores the need for gathering more information on the fluid status of dialysis patients and suggests utilizing measurements of bioimpedance, dialysate bolus-derived absolute blood volume, and lung ultrasound for fluid management. The proposal is to use machine learning to create flexible target weight prescriptions and never give up on finding effective approaches to fluid management in hemodialysis.
KIDNEY INTERNATIONAL
(2022)
Article
Peripheral Vascular Disease
Charalampos Loutradis, Pantelis A. Sarafidis, Robert Ekart, Ioannis Tsouchnikas, Christodoulos Papadopoulos, Vasileios Kamperidis, Maria Eleni Alexandrou, Charles J. Ferro, Aikaterini Papagianni, Gerard London, Francesca Mallamaci, Carmine Zoccali
Summary: The study shows that dry-weight reduction guided by lung ultrasound can effectively decrease ambulatory blood pressure levels in hypertensive hemodialysis patients in the long term. This intervention was associated with a greater reduction in systolic blood pressure compared to standard care, as well as a lower incidence of intradialytic hypotension.
JOURNAL OF HYPERTENSION
(2021)
Review
Transplantation
Charalampos Loutradis, Pantelis A. Sarafidis, Charles J. Ferro, Carmine Zoccali
Summary: Volume overload in haemodialysis patients is associated with hypertension and cardiac dysfunction, posing a major risk factor for all-cause and cardiovascular mortality. While methods to accurately evaluate dry weight and diagnose subclinical volume overload are still uncertain in clinical practice, bioimpedance spectroscopy and lung ultrasound have shown promising results. Gradual fluid removal and distribution over a sufficient time window is crucial for cardiovascular tolerance in volume-expanded HD patients.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Urology & Nephrology
Simon J. Davies, David Coyle, Elizabeth J. Lindley, David Keane, John Belcher, Fergus J. Caskey, Indranil Dasgupta, Andrew Davenport, Ken Farrington, Sandip Mitra, Paula Ormandy, Martin Wilkie, Jamie MacDonald, Mandana Zanganeh, Lazaros Andronis, Ivonne Solis-Trapala, Julius Sim
Summary: Avoiding excessive dialysis-associated volume depletion may help preserve residual kidney function. A randomized controlled trial was conducted to examine whether knowledge of estimated normally hydrated weight could reduce the rate of loss of residual kidney function. The results showed that using a standardized clinical protocol for fluid assessment can effectively preserve residual kidney function without the need for bioimpedance measurements.
KIDNEY INTERNATIONAL
(2023)
Article
Hematology
Theerasak Tangwonglert, Andrew Davenport
Summary: Arterial stiffness, measured by pulse wave velocity (PWV), is known to increase in hemodialysis (HD) patients, but a study found no overall change in PWV after 5 years, with some patients experiencing an increase while others a decrease. Changes in PWV were not associated with extracellular water (ECW) levels, but were correlated with changes in pre-dialytic systolic blood pressure (SBP). Interventional studies are needed to determine if targeted blood pressure control can reduce PWV in HD patients.
BLOOD PURIFICATION
(2021)
Article
Pediatrics
Antoine Mouche, Cyrielle Parmentier, Fatma Fendri, Claire Herbez-Rea, Anne Couderc, Laurene Dehoux, Marina Avramescu, Theresa Kwon, Julien Hogan, Jean-Daniel Delbet, Tim Ulinski
Summary: This study suggests that the prescription of dry weight (DW) for children on hemodialysis (HD) should not solely rely on clinical evaluation, particularly blood pressure (BP), but should also include other useful parameters. Cardiac biomarkers, especially BNP, showed a good correlation with hydration status evaluated by bioimpedance spectroscopy (BIS), which could provide valuable information for individual patient management and DW assessment.
PEDIATRIC NEPHROLOGY
(2023)
Article
Urology & Nephrology
Gwangho Choi, Ho Joong Yoon, Young Jin Song, Hae Min Jeong, Jae Eon Gu, Miyeun Han, Seok Hyung Kim, Jong-Woo Yoon, Hyunsuk Kim
Summary: This study compared the measurements of hemodialysis patients' estimated target weight and ECW/TBW obtained lying down using the InBody S10 device to those obtained in the standing position using the InBody 770 device. The results showed consistent measurements in both pre- and post-hemodialysis states.
Article
Engineering, Electrical & Electronic
Tae-Ho Kim, Chao Bao, Ziniu Chen, Woo Soo Kim
Summary: In this study, a dry electrode inspired by origami and the suction mechanism of leeches was developed for reliable blood pressure monitoring. The electrode showed promising results in detecting ECG and photoplethysmography signals, demonstrating its potential for accurate blood pressure measurement.
NPJ FLEXIBLE ELECTRONICS
(2022)
Article
Peripheral Vascular Disease
Wenjin Liu, Yinyin Ye, Lulu Wang, Chaoqing Gao, Youwei Bai, Hong Chu, Wei Fan, Zhuxing Sun, Liang Wang, Xiurong Li, Junwei Yang
Summary: Central blood pressure is predictive of all-cause mortality and cardiovascular events in dialysis patients, but its prognostic value does not outperform ambulatory peripheral blood pressure.
JOURNAL OF HYPERTENSION
(2022)
Article
Environmental Sciences
Richard Remigio, Rodman Turpin, Jochen G. Raimann, Peter Kotanko, Frank W. Maddux, Amy Rebecca Sapkota, Xin-Zhong Liang, Robin Puett, Xin He, Amir Sapkota
Summary: The study confirmed the association between ambient temperature, all-cause hospital admissions, and all-cause mortality increase. Findings suggest that pre-dialysis systolic blood pressure (preSBP) and interdialytic weight gain (IDWG) can act as independent mediators. However, in combined pathway models, changes in preSBP and IDWG had little intermediary effect on the association between temperature and all-cause hospital admissions and mortality.
ENVIRONMENTAL RESEARCH
(2022)
