Review
Oncology
Jenneke E. van Atteveld, Iris E. Verhagen, Marry M. van den Heuvel-Eibrink, Hanneke M. van Santen, Inge M. van Der Sluis, Natascia Di Iorgi, Jill H. Simmons, Leanne M. Ward, Sebastian J. C. M. M. Neggers
Summary: The effectiveness of vitamin D supplementation for children with cancer in enhancing bone strength is still uncertain, as studies have shown no significant association between vitamin D (and calcium) supplementation and BMD or fracture frequency. It is recommended to follow standard national guidelines, periodically monitor 25OHD levels, and supplement vitamin D/calcium for children with low levels to maintain adequate levels.
Review
Food Science & Technology
Amin Gasmi, Geir Bjorklund, Massimiliano Peana, Pavan Kumar Mujawdiya, Lyudmila Pivina, Adrien Ongenae, Salva Piscopo, Beatrice Severin
Summary: Calcium is essential for bone health and nerve signaling, while phosphorus is a key component of ATP and helps regulate metabolic energy. Vitamins D and K are crucial for the absorption and excretion of calcium and phosphorus, with vitamin D playing a regulatory role in various bodily functions.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Nutrition & Dietetics
Marta Zieminska, Beata Sieklucka, Krystyna Pawlak
Summary: Vitamin K and vitamin D deficiency in chronic kidney disease can lead to impaired bone health and increased risk of fractures. Currently, there is no consensus on the optimal supplementation approach for these vitamins in CKD patients.
Article
Biochemistry & Molecular Biology
Philip R. Fischer, Neamat Almasri
Summary: Nutritional rickets can be caused by either vitamin D deficiency or insufficient dietary intake of calcium, and the combined deficiencies of calcium and vitamin D interact. Other factors also play a role in the pathogenesis of nutritional rickets.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2022)
Article
Nutrition & Dietetics
Pilar Palmrich, Alexandra Thajer, Nawa Schirwani, Christina Haberl, Harald Zeisler, Robin Ristl, Julia Binder
Summary: This study indicates that the majority of pregnant women are deficient in vitamin D during pregnancy, despite the intake of pregnancy vitamins containing vitamin D. Therefore, individualized vitamin D assessment should be considered to ensure adequate supplementation and prevention of hypovitaminosis D.
Review
Nutrition & Dietetics
Michael McBurney, Jeffrey B. Blumberg, Rebecca B. Costello, Manfred Eggersdorfer, John W. Erdman, William S. Harris, Elizabeth J. Johnson, Susan Hazels Mitmesser, Robert C. Post, Deshanie Rai, Leon J. Schurgers
Summary: The US Dietary Guidelines provide dietary recommendations to meet nutrient needs, but there is still a prevalence of under-consumed nutrients. It is suggested to update nutrient intake recommendations based on biomarker levels and establish DRIs for bioactive compounds.
Review
Nutrition & Dietetics
Francesco Bertoldo, Luisella Cianferotti, Marco Di Monaco, Alberto Falchetti, Angelo Fassio, Davide Gatti, Luigi Gennari, Sandro Giannini, Giuseppe Girasole, Stefano Gonnelli, Nazzarena Malavolta, Salvatore Minisola, Mario Pedrazzoni, Domenico Rendina, Maurizio Rossini, Iacopo Chiodini
Summary: In recent years, there has been an increase in the prescriptions for serum 25(OH)D levels assay and vitamin D supplementation, as well as the related costs. Italy, like many other countries, has a high risk of vitamin D deficiency, despite the use of supplements. There is a significant gap in the treatment of osteoporosis, with many patients not receiving appropriate therapy, which increases the risk of re-fracture and mortality.
Review
Nutrition & Dietetics
Chao-Yi Wu, Huang-Yu Yang, Shue-Fen Luo, Jing-Long Huang, Jenn-Haung Lai
Summary: Vitamin D plays an important role in bone health and immune regulation. Juvenile idiopathic arthritis is a chronic inflammatory joint disease, and vitamin D may have potential effects on its manifestations and outcomes.
Article
Nutrition & Dietetics
Alicja Kolodziejczyk-Nowotarska, Renata Bokiniec, Joanna Seliga-Siwecka
Summary: A study was conducted to assess the effectiveness of monitored vitamin D supplementation in preterm infants. Results showed that a higher percentage of infants in the monitored group had safe vitamin D levels, while potential vitamin D toxicity was observed in the standard treatment group. Therefore, vitamin D intake should be between 800-1000 IU and monitored to avoid overdose.
Article
Biochemistry & Molecular Biology
Davide Serrano, Federica Bellerba, Harriet Johansson, Debora Macis, Valentina Aristarco, Chiara A. Accornero, Aliana Guerrieri-Gonzaga, Cristina M. Trovato, Maria Giulia Zampino, Emanuela Omodeo Sale, Bernardo Bonanni, Sara Gandini, Patrizia Gnagnarella
Summary: Vitamin D deficiency is associated with colorectal cancer (CRC), while adherence to World Cancer Research Fund (WCRF) recommendations significantly reduces the risk of developing CRC. In a randomized trial, CRC patients showed gender and microbiota-specific responses to Vitamin D supplementation. Following WCRF recommendations was associated with lower levels of leptin and IL-6, as well as a lower risk of events. Vitamin D supplementation did not have a significant impact on circulating biomarkers or follow-up events.
Review
Endocrinology & Metabolism
Andrea Giustina, Luigi di Filippo, Antonio Facciorusso, Robert A. Adler, Neil Binkley, Jens Bollerslev, Roger Bouillon, Felipe F. Casanueva, Giulia Martina Cavestro, Marlene Chakhtoura, Caterina Conte, Lorenzo M. Donini, Peter R. Ebeling, Angelo Fassio, Stefano Frara, Claudia Gagnon, Giovanni Latella, Claudio Marcocci, Jeffrey I. Mechanick, Salvatore Minisola, Rene Rizzoli, Ferruccio Santini, Joseph L. Shaker, Christopher Sempos, Fabio Massimo Ulivieri, Jyrki K. Virtanen, Nicola Napoli, Anne L. Schafer, John P. Bilezikian
Summary: Bariatric surgery is associated with a decrease in 25(OH) vitamin D levels and increased risk of skeletal complications. Guidelines for assessing and supplementing vitamin D in bariatric patients before and after surgery are lacking. This systematic review and meta-analysis provide recommendations for vitamin D management in bariatric patients based on published experience. Vitamin D levels should be assessed pre- and postoperatively in all bariatric surgery patients, and high-dose supplementation is recommended after surgery.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2023)
Article
Nutrition & Dietetics
Jakub Erdmann, Michal Wicinski, Pawel Szyperski, Sandra Gajewska, Jakub Ohla, Maciej Slupski
Summary: Vitamin D helps balance calcium and phosphorus levels for proper bone structure and has a variety of potential benefits. The authors investigated its preventive effects on vertebral fractures, hip fractures, stress fractures, and pediatric fractures, as well as its impact on recovery and severity of fractures. Vitamin D supplementation may reduce hip fracture risk through decreased bone turnover, fewer falls, and improved muscle function. It also appears to lower stress fracture risk in athletes and military recruits. However, inconsistencies were found in the relationship between vitamin D supplementation and reduced vertebral fracture risk. The preventive effect of vitamin D on pediatric fractures seems unlikely.
Article
Physiology
Xiaomin Sun, Wenjuan Xiao, Zhongying Li, Sirui Zhou, Mengyue Dong, Cong Huang, Yan Ma, Bo Gou
Summary: This study aimed to assess the effects of a 12-week vitamin D and endurance exercise intervention on bone health, body composition, and physical performance among patients with type 2 diabetes. The results showed that vitamin D supplementation had significant effects on maintaining bone health, while exercise had a main effect on reducing body fat percentage.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Nutrition & Dietetics
Feitong Wu, Ghada El-Hajj Fuleihan, Guoqi Cai, Christel Lamberg-Allardt, Heli T. Viljakainen, Maya Rahme, Ida M. Gronborg, Rikke Andersen, Anuradha Khadilkar, M. Zulf Mughal, Christian Molgaard, Anni Larnkjaer, Kun Zhu, Richard D. Riley, Tania Winzenberg
Summary: This study, which analyzed data from multiple randomized controlled trials, found that vitamin D supplementation has limited benefits for bone density in healthy children and adolescents, regardless of their baseline vitamin D levels.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Letter
Public, Environmental & Occupational Health
Vivek Dixit, Bhavuk Garg, Nishank Mehta, James Pegrum, Dinesh Dhanwal
Summary: Responsive immunity plays a vital role in combating infections, while Vitamin D deficiency globally affects both musculoskeletal health and immunity status. Establishing the role of vitamin D in pathogen destruction is crucial during the COVID-19 pandemic. Implementing a vitamin D awareness program at school level could be an effective health governance policy to educate populations on the importance of vitamin D in overall health.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2021)