Article
Medicine, General & Internal
Tanya Deneva, Youri Ianakiev, Oliana Boykinova
Summary: The study aims to analyze salivary mental stress biomarkers in hospitalized patients with COVID-19 and determine their potential relationship with stress symptoms.
FRONTIERS IN MEDICINE
(2022)
Article
Food Science & Technology
Carolina Martins Finassi, Leandro A. Calixto, Wilson Segura, Mariana Zuccherato Bocato, Fernando Barbosa Jr, Fernando L. A. Fonseca, Elsa Lamy, Paula Midori Castelo
Summary: This study aimed to assess the excretion of aspartame in saliva and the levels of salivary insulin, total protein, and alpha amylase in response to the intake of sweetened beverages. The results showed that artificially sweetened drinks and beverages with sucrose left a lingering sweet/sour residual flavor in saliva, and saliva aspartame levels were only correlated with insulin levels after the intake of diet soft drinks.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Nattinee Jantaratnotai, Krittiphat Rungnapapaisarn, Piyanee Ratanachamnong, Praewpat Pachimsawat
Summary: This study compared the diurnal patterns of cortisol, amylase, and chromogranin A in saliva. The results showed that cortisol exhibited the least variation among individuals, while chromogranin A showed the highest variation. Factors such as BMI, age, and gender were found to affect the levels of these biomarkers.
ARCHIVES OF ORAL BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Nattinee Jantaratnotai, Thi Kim Anh Do, Manita Tammayan, Praewpat Pachimsawat
Summary: This study aimed to investigate how different baseline states of mind affect the diurnal patterns of salivary stress biomarkers. The results showed that cortisol and alpha-amylase levels were highest on stressful days and lowest on relaxing days, while chromogranin A levels showed the opposite pattern. The study also found that mindfulness practice had different effects on these biomarkers compared to a general relaxed state of mind.
Review
Biochemistry & Molecular Biology
Katarina Jansakova, Klaudia Kyselicova, Daniela Ostatnikova, Gabriela Repiska
Summary: Saliva, as a potential alternative to other body fluids, offers a complex view on the current state of the individual with its sources of nucleic acid of both human and microbial origin, protein, and non-protein molecules. Using salivary markers may simplify ASD screening and potentially reveal the etiopathogenesis of ASD, with the advantage of easier recruitment of neurotypical counterparts for studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Neurosciences
Marine Thieux, Aurore Guyon, Vania Herbillon, Lydie Merle, Jean-Philippe Lachaux, Sabine Plancoulaine, Laurent Seugnet, Patricia Franco
Summary: The study found that sleep quality and difficulty falling asleep the night before travel were associated with sleepiness and attentional performance in drivers. 47% of drivers scored pathologically high on the Stanford Sleepiness Scale during the test.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Behavioral Sciences
Ecaterina Stribitcaia, Catherine Gibbons, Joanna Sier, Christine Boesch, John Blundell, Graham Finlayson, Anwesha Sarkar
Summary: With the rise in overweight and obesity, novel strategies are needed to address the issue. This study investigated the effects of preloads with varying oral lubricating properties on appetite, food intake, and salivary biomarkers in healthy participants. While high lubricating preloads temporarily reduced hunger and desire to eat, the effects were not significant after baseline values were controlled for.
Review
Chemistry, Analytical
Veerappan Mani, Tutku Beduk, Walaa Khushaim, Ayse Elcin Ceylan, Suna Timur, Otto S. Wolfbeis, Khaled Nabil Salama
Summary: Salivary markers analysis has become a promising non-invasive approach for easy, safe, and pain-free monitoring, with the potential to impact clinical diagnosis and management. Advancements in sensing technology, novel materials, innovative fabrication technologies, and sampling accuracy have established saliva as a routine fluid for analysis, with applications in diagnosing various diseases.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Cristina Tortolini, Valeria Gigli, Antonio Angeloni, Federico Tasca, Nguyen T. K. Thanh, Riccarda Antiochia
Summary: The development of a novel voltammetric immunosensor for the detection of salivary MMP-8 at the point-of-care is described. The sensor showed good performance and comparable results to the conventional ELISA method when tested in real saliva samples. This biosensor is single-use, cost-effective, and requires a small quantity of test medium and a short preparation time.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Rabia Semsi, Umut Kokbas, Burak Arslan, Erdal Ergunol, Levent Kayrin, Aylin Sepici Dincel
Summary: The study compared salivary cortisol and amylase levels measured by three different analytical methods to discuss stress level alterations in samples. The biosensor method showed good correlation with ELISA in determining salivary cortisol levels and could be offered as an alternative to ELISA due to its effectiveness, cost-efficiency, speed, and specificity.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Review
Pathology
Sompop Bencharit, Robert G. Redenz, Erica R. Brody, Harmeet Chiang
Summary: The study aimed to define and characterize salivary biomarker changes in sleep apnea. Findings show that biomarkers like alpha-amylase, myeloperoxidase, and IL-6 are associated with OSA. Salivary cortisol and alpha-amylase appear to be related to the severity of OSA and its treatment outcomes.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
(2021)
Article
Food Science & Technology
Jennifer L. Goza, Gregory R. Ziegler, Josephine Wee, John E. Hayes, Helene Hopfer
Summary: This study found that salivary alpha-amylase activity and flow rate can influence the flavor perception of starch-guest inclusion complexes, highlighting their importance in food sensory experiences. TCATA and CATA were identified as effective tools for tracking flavor release systems over an extended period.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Ana Glavina, Liborija Lugovic-Mihic, Dinko Martinovic, Livia Cigic, Leida Tandara, Marino Lukenda, Dolores Biocina-Lukenda, Daniela Supe-Domic
Summary: This study aimed to examine the relationship between salivary stress biomarkers (cortisol, alpha-amylase) and the psychological profile of patients with oral lichen planus (OLP) and primary burning mouth syndrome (BMS). The results showed that patients with BMS had higher cortisol concentrations and alpha-amylase activity, as well as higher scores for depression, anxiety, and stress, compared to patients with OLP and control subjects. There was a strong positive correlation between anxiety and depression, stress and depression, and stress and anxiety in both patient groups. The study concluded that an interdisciplinary psychoneuroimmunological approach is important for both OLP and BMS patients.
Article
Veterinary Sciences
Elisa Giaretta, Paolo Mongillo, Laura Da Dalt, Matteo Gianesella, Martina Bortoletti, Lorenzo Degano, Daniele Vicario, Gianfranco Gabai
Summary: Measuring salivary hormone levels can help assess the stress response in animals and select for robust and resilient genetic traits. This study found that repeated handling reduced the hormone response, while environmental temperature and humidity had a minor effect on hormone levels.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Multidisciplinary Sciences
Haimei Xie, Xiaomei Zheng, Ye Huang, Weihao Li, Wenkai Wang, Qiao Li, Jiangtao Hou, Lulu Luo, Xiuying Kuang, Chuan-Quan Lin
Summary: Saliva composition has diurnal variations, which are not affected by citric acid stimulation. The variation characteristics of male and female under resting state and acid stimulation are basically the same, with the trend of salivary alpha-amylase activity being opposite to that of cortisol.