Review
Chemistry, Multidisciplinary
Akeemat O. Tijani, Jivesh Garg, Dorcas Frempong, Gabrielle Verana, Jagroop Kaur, Ramesh Joga, Chetan D. Sabanis, Sandeep Kumar, Neeraj Kumar, Ashana Puri
Summary: Substance use disorders (SUDs) are a major cause of death and health effects globally, with drug therapy being the main approach for management, particularly with sustained release designs for improved tolerance and treatment outcomes.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Pediatrics
Junhan Cho, Lorraine Kelley-Quon, Jessica L. Barrington-Trimis, Afton Kechter, Sarah Axeen, Adam M. Leventhal
Summary: The study found that adolescent nonmedical prescription opioid use is associated with behavioral health problems such as major depression, hypomania or mania, cannabis, alcohol, and other drug use problems. Adolescents with these issues were more likely to use nonmedical prescription opioids. Furthermore, the higher the comorbidity of behavioral health problems, the greater the risk of subsequent nonmedical prescription opioid use.
Article
Psychiatry
Chintan Trivedi, Rupak Desai, John Rafael, Stephanie Bui, Karrar Husain, Abid Rizvi, Mudasar Hassan, Zeeshan Mansuri, Shailesh Jain
Summary: This study investigated and compared the prevalence of mental health disorders (MHD) and substance use disorders (SUD) in hospitalized patients between 2007 and 2017. The results showed a significant increase in the prevalence of substance use disorders and psychiatric disorders within a decade among hospitalized patients aged 18-44 years. The most notable increases were observed in amphetamine use disorders and anxiety disorders. Suicide and intentional self-inflicted injury increased across all races.
PSYCHIATRY RESEARCH
(2022)
Article
Psychiatry
Harrieth P. P. Ndumwa, Belinda J. J. Njiro, Joel M. M. Francis, Thomas Kawala, Charles J. J. Msenga, Ezekiel Matola, Juhudi Mhonda, Hillary Corbin, Omary Ubuguyu, Samuel Likindikoki
Summary: The study examines substance use disorders among Police Officers in urban Tanzania. The results indicate that the prevalence of alcohol and tobacco use in the past three months among the officers is 31.3% and 6.3% respectively. Furthermore, 13.3% meet the criteria for potential alcohol use disorder (AUD) and 6.2% for potential tobacco use disorder (TUD). The study reveals that depression is an important factor for potential AUD and TUD among Police Officers.
Review
Psychiatry
Malein Pacho, Claudia Aymerich, Borja Pedruzo, Gonzalo Salazar de Pablo, Eva Sesma, Marta Bordenave, Rodrigo Dieguez, Itziar Lopez-Zorroza, Jon Herrero, Maria Laborda, Aranzazu Fernandez-Rivas, Clemente Garcia-Rizo, Miguel Angel Gonzalez-Torres, Ana Catalan
Summary: This meta-analysis provides evidence that pregnant women who use substances have an increased risk of developing postpartum depression, especially those who use multiple substances or tobacco. However, caution should be exercised in interpreting the association between alcohol use and risk, as it did not reach statistical significance.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Behavioral Sciences
Sandra Lopez-Leon, Yeimy Gonzalez-Giraldo, Talia Wegman-Ostrosky, Diego A. Forero
Summary: This article provides a comprehensive overview of genetic studies on substance use disorders (SUD) through an umbrella review, revealing alcohol and tobacco as the most studied substances and cannabis, opioids, and cocaine as the least studied. Several genes are associated with multiple SUDs, with SLC6A4 showing the highest OR values across all addictions. GWAS confirmed the role of CHRNA5 in nicotine dependence and identified new candidate genes for further functional analyses in other SUDs.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Review
Health Care Sciences & Services
Yu Chi, Huai-yu Chen
Summary: This scoping review examines the use of Reddit as a data source for substance use research. Analyzing Reddit data can be useful for understanding patterns and user experiences related to substance use, despite its limitations. The review also identifies gaps in the literature and suggests directions for future research.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Health Care Sciences & Services
Charles R. Jonassaint, Julia O'Brien, Emily Nardo, Robert Feldman, Michael Stanton, Laura DeCastro, Kaleab Z. Abebe
Summary: This study found that Black American adults with sickle cell disease (SCD) are more likely to have alcohol use disorders compared to those with other chronic conditions or no chronic conditions, but not drug use disorders. This suggests a need for further research to understand the factors contributing to increased risk of alcohol use disorders in SCD patients.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Psychology, Clinical
Shira Maguen, Brandon Nichter, Sonya B. Norman, Robert H. Pietrzak
Summary: This study aimed to investigate the impact of risk factors associated with exposure to potentially morally injurious events (PMIEs) on substance use disorders (SUDs) among veterans. The results showed that perpetration was associated with increased risk of lifetime AUD and SUD, witnessing was associated with increased risk of past-year DUD and SUD, and betrayal was associated with increased risk of past-year AUD. These findings are important for the assessment, treatment, and care planning of SUDs among veterans.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Raimondo Maria Pavarin, Chiara Fabbri, Diana De Ronchi
Summary: People with Substance or Alcohol Use Disorders (SUDs/AUDs) are more susceptible to COVID-19 infection, with higher hospitalization and mortality rates.
PSYCHIATRY RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Ayomide T. David, Vinita Sharma, Lorna Bittencourt, Kelly K. Gurka, Juan Guillermo Perez-Carreno, Catalina Lopez-Quintero
Summary: This study examines the relationship between Serious Psychological Distress (SPD) and the quantity or frequency of substance use among pregnant women in the United States (US). The results show that pregnant women experiencing SPD had higher rates of smoking, binge drinking, and cannabis use compared to those who did not report SPD.
PREVENTIVE MEDICINE
(2023)
Review
Medicine, General & Internal
Gihan ELNahas, Florence Thibaut
Summary: There has been a significant increase in the use of psychoactive drugs by women of childbearing age and during pregnancy. The use of illicit drugs, alcohol, and tobacco during pregnancy poses serious health risks for both the mother and the baby. This review highlights the current trends in substance use during pregnancy and the associated consequences. It emphasizes the need for informing women about the harmful effects of using psychoactive substances during pregnancy and promoting prevention and intervention measures.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Integrative & Complementary Medicine
Berney Sylvain, Broers Barbara, Gaspoz Jean-Michel, Favrod-Coune Thierry
Summary: A survey conducted in Switzerland found that approximately 62.5% of patients with substance use disorders (SUD) have used or tried complementary and alternative medicines (CAM), with at least half of them using CAM for comorbid disorders rather than specifically for their SUD. The majority of participants expressed a desire for CAM to be integrated into the healthcare system and believed that their general practitioners should be able to refer them to CAM specialists if needed.
EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
(2022)
Article
Medicine, General & Internal
Sean Esteban McCabe, John E. Schulenberg, Timothy E. Wilens, Ty S. Schepis, Vita V. McCabe, Philip T. Veliz
Summary: This study investigated the prevalence and association between stimulant therapy for ADHD and nonmedical use of prescription stimulants (NUPS) among US secondary school students. The findings revealed that schools with a higher proportion of students using ADHD therapy were more likely to have students engaging in nonmedical use of prescription stimulants in the past year. The study suggests the importance of school assessments, risk-reduction strategies, and preventive efforts to reduce NUPS.
Article
Substance Abuse
Paul Welford, Anna-Karin Danielsson, Helio Manhica
Summary: This study found that exposure to parental substance use disorder in Sweden is associated with an increased risk of being not in education, employment or training during early adulthood. The risks were highest at age 17-19 and decreased with greater age.
