Article
Surgery
Adrian Diaz, Anna Schoenbrunner, Timothy M. Pawlik
Summary: Despite a decrease in the number of rural hospitals over the past decade, there has been an increase in the number of large, academic medical centers. This has resulted in a significant increase in the number of people living outside a 60-minute driving range to a hospital capable of performing surgery.
Article
Hematology
Ruchika Goel, Xianming Zhu, Eshan U. Patel, Elizabeth P. Crowe, Paul M. Ness, Louis M. Katz, Evan M. Bloch, Aaron A. R. Tobian
Summary: The study evaluated national trends in blood transfusions in the US from 2015 to 2018, finding a decrease in RBC and plasma transfusions, stable platelet transfusions, and a significant increase in cryoprecipitate utilization. This increase in cryoprecipitate use may reflect the wider adoption of management strategies for hypofibrinogenemia and hemostasis testing in coagulopathic patients.
Article
Medicine, General & Internal
Amos Lal, Kevin John John, Ajay Kumar Mishra, Akil Adrian Sherif
Summary: Little is known about the differences in healthcare resource utilization between non-fatal and fatal firearm-related injuries. This study utilized the National Inpatient Sample (NIS) database to examine these differences and found that individuals with lower income, males, young Americans, and racial minorities were disproportionately affected. The group with fatal injuries had shorter hospital stays but higher overall and per day hospitalization costs compared to the group with non-fatal injuries.
INTERNAL AND EMERGENCY MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Madeline Bertha, Kerby Shedden, Jessica Mellinger
Summary: The rate of alcohol-related liver disease and mortality has been increasing among women, particularly young women and Native Americans. This highlights the need for targeted public health interventions for these populations.
LIVER INTERNATIONAL
(2022)
Review
Cardiac & Cardiovascular Systems
Dhrubajyoti Bandyopadhyay, Upasana Banerjee, Adrija Hajra, Sandipan Chakraborty, Birendra Amgai, Raktim K. Ghosh, Faris I. Haddadin, Vivek A. Modi, Kaushik Sinha, Wilbert S. Aronow, Prakash Deedwania, Carl J. Lavie
Summary: The study demonstrated a significant increasing trend in cardiovascular complications in RA patients, with a significant increase in the proportion of patients with cardiovascular comorbidities.
CURRENT PROBLEMS IN CARDIOLOGY
(2021)
Article
Pediatrics
Sonam Sidhu, Ava Mandelbaum, Vishal Dobaria, Catherine G. Williamson, Zachary Tran, Veronica Sullins, Peyman Benharash
Summary: The study characterized hospitalization costs attributable to gun-related injuries in children in the US, revealing a significant socioeconomic burden and increasing resource use over time. The findings underscore the urgent need for further research and advocacy to reduce the prevalence and social impact of pediatric gun violence.
JOURNAL OF PEDIATRICS
(2021)
Article
Gastroenterology & Hepatology
Jeff Liang, Christopher V. Almario, William D. Chey, Carolyn S. Higgins, Brennan M. R. Spiegel
Summary: In this study of a nationally representative data set in the United States, the prevalence, symptom severity, and medication use in individuals with Rome IV chronic idiopathic constipation (CIC), opioid-induced constipation (OIC), and opioid-exacerbated constipation (OEC) were assessed. The results showed that OIC and OEC were less prevalent than CIC, but individuals with OIC and OEC had more severe constipation symptoms and were more likely to use prescription medication.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Christopher Ma, Stephen E. Congly, Kerri L. Novak, Paul J. Belletrutti, Maitreyi Raman, Matthew Woo, Christopher N. Andrews, Yasmin Nasser
Summary: The management of chronic symptomatic functional bowel disorders (FBDs) in the United States incurs considerable healthcare resource use and cost, with pharmacologic therapies being more commonly prescribed than nonpharmacologic interventions. Combination treatment strategies are more likely to be implemented by primary care physicians, highlighting the need to improve comprehensive FBD management.
Article
Orthopedics
Ville T. Ponkilainen, Tuomas T. Huttunen, Marko H. Neva, Liisa Pekkanen, Jussi P. Repo, Ville M. Mattila
Summary: The study reveals an increase in the incidence of lumbar spine decompressions and fusions in Finland between 1997 and 2018, possibly due to advancements in surgical techniques, an aging population, and increased evidence supporting surgical treatment for spinal pathologies.
Article
Cardiac & Cardiovascular Systems
Aarti Thakkar, Yaa A. Kwapong, Harsh Patel, Anum S. Minhas, Arthur J. Vaught, Nicole Gavin, Sammy Zakaria, Roger S. Blumenthal, Katherine C. Wu, Jonathan Chrispin, Sourbha S. Dani, Garima Sharma
Summary: This study used the National Inpatient Sample database to analyze the trends of arrhythmias among women hospitalized for delivery aged 18-49 years. The results showed an increasing prevalence of arrhythmias during delivery hospitalizations between 2009 and 2019. Age > 35 years and Black race were associated with a higher arrhythmia burden, while factors such as valvular disease, heart failure, and prior myocardial infarction were associated with an increased risk of arrhythmias. Delivery hospitalizations with a history of arrhythmia were more likely to be complicated by all-cause in-hospital mortality, cardiovascular, and adverse pregnancy outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Immunology
Madeleine Baker-Goering, Kakoli Roy, Chris Edens, Sarah Collier
Summary: Based on estimates of medical costs and productivity losses, the lifetime economic burden of 2014 Legionnaires' disease cases in the United States is estimated to be around $835 million, including $21 million due to absenteeism and $412 million due to premature deaths.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Critical Care Medicine
Shehabaldin Alqalyoobi, Shu-Yi Liao, Waqas Qureshi, Ogugua Ndili Obi
Summary: Hospitalization rates for patients with pulmonary sarcoidosis and respiratory failure are increasing in the United States, but inpatient mortality rates caused by respiratory failure have declined. Older age, respiratory failure, pulmonary hypertension, and frailty are important predictors of inpatient mortality in hospitalized patients with pulmonary sarcoidosis.
Article
Microbiology
Kaitlin Benedict, Ian Hennessee, Jeremy A. W. Gold, Dallas J. Smith, Samantha Williams, Mitsuru Toda
Summary: This study analyzed blastomycosis-associated hospitalizations in the United States from 2010 to 2020. The results showed a relatively low hospitalization rate with no apparent temporal trend, but higher rates among individuals aged 65 and older and males. The in-hospital death rate increased during this period and was associated with age, chronic obstructive pulmonary disease, and malignancy.
Review
Immunology
Harris Majeed, Karthik Gangu, Shazib Sagheer, Ishan Garg, Umair Khan, Hina Shuja, Aniesh Bobba, Prabal Chourasia, Rahul Shekhar, Sindhu Reddy Avula, Abu Baker Sheikh
Summary: The COVID-19 pandemic has negatively impacted inpatient outcomes for patients with non-ST-segment elevation myocardial infarction (NSTEMI), leading to increased mortality, longer hospital stays, higher hospitalization costs, and decreased utilization of invasive cardiac procedures.
Article
Surgery
Tonga Nfor, Ehab Dababneh, M. Fuad Jan, Jayant Khitha, Suhail Q. Allaqaband, Tanvir Bajwa, Mark W. Mewissen
Summary: The use of atherectomy in peripheral vascular interventions (PVIs) has significantly increased from 2010 to 2019. There is wide regional variability in atherectomy use, which seems to be driven more strongly by nonclinical factors.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Gastroenterology & Hepatology
Ayesha Shah, Saravana Ruban Gurusamy, Teressa Hansen, Gavin Callaghan, Nicholas J. Talley, Natasha Koloski, Marjorie M. Walker, Michael P. Jones, Mark Morrison, Gerald J. Holtmann
Summary: The study found that in FD patients, antimicrobial therapy with rifaximin is effective in improving symptoms and is not influenced by concomitant IBS symptoms. The effects of the treatment persisted for 6 weeks post-treatment.
DIGESTIVE DISEASES AND SCIENCES
(2022)
Article
Gastroenterology & Hepatology
David T. McNaughton, Anna Andreasson, Brjann Ljotsson, Alissa P. Beath, Julia M. Hush, Gunnar Ljunggren, Peter T. Schmidt, Nicholas J. Talley, Lars Agreus, Michael P. Jones
Summary: The study found that quality of life domains did not moderate the relationship between gastrointestinal symptoms and healthcare seeking, suggesting the need for further research on other factors.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Psychology, Developmental
Ronald M. Rapee, Lauren F. McLellan, Talia Carl, Nora Trompeter, Jennifer L. Hudson, Michael P. Jones, Viviana M. Wuthrich
Summary: This study compared a generic cognitive-behavioral therapy (CBT) treatment for pediatric social anxiety disorder against a modified treatment. The results showed no significant difference between the two treatments in terms of remission of social anxiety disorder. Although the modified treatment showed some improvement in one maintaining process, overall there was little evidence that it significantly improved treatment outcomes for pediatric social anxiety disorder.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Emergency Medicine
Nicholas M. Mohr, Uche Okoro, Karisa K. Harland, Brian M. Fuller, Kalyn Campbell, Morgan B. Swanson, Cole Wymore, Brett Faine, Anne Zepeski, Edith A. Parker, Luke Mack, Amanda Bell, Katie DeJong, Keith Mueller, Elizabeth Chrischilles, Christopher R. Carpenter, Kelli Wallace, Michael P. Jones, Marcia M. Ward
Summary: The study aimed to determine if provider-to-provider tele-emergency department (tele-ED) care is associated with better outcomes for patients in rural emergency departments (EDs). The study used medical records of sepsis patients from rural hospitals in a tele-ED network. The results showed that tele-ED care did not significantly improve 28-day hospital-free days, inhospital mortality, or guideline adherence compared to standard care. However, in a subgroup of patients treated by advanced practice providers, tele-ED was associated with lower mortality rates.
ANNALS OF EMERGENCY MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Natasha A. Koloski, Michael Jones, Marjorie M. Walker, Michael Horowitz, Gerald Holtmann, Nicholas J. Talley
Summary: Diabetes is an independent risk factor for an increased frequency of gastrointestinal symptoms, adjusting for lifestyle and psychological factors.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Ayesha Shah, Seungha Kang, Nicholas J. Talley, Anh Do, Marjorie M. Walker, Erin R. Shanahan, Natasha A. Koloski, Michael P. Jones, Simon Keely, Mark Morrison, Gerald J. Holtmann
Summary: Patients with functional gastrointestinal disorders (FGIDs) often report intolerance to wheat products. This study compared various factors, including gastrointestinal symptoms, sensory function, psychiatric comorbidities, gut-homing immune cells, and duodenal mucosa-associated microbiome (d-MAM), between FGID patients and controls with and without self-reported wheat sensitivity (SR-NCWS). The results showed that anxiety, visceral sensory function, and specific bacterial taxa were associated with FGID, while gut-homing T-cells were associated with SR-NCWS. The study also found differences in the bacterial genera between the FGID subtypes and controls. Patients with FGID, with or without SR-NCWS, showed increased symptom response and anxiety scores compared to controls.
Article
Gastroenterology & Hepatology
Ayesha Shah, Sahar Pakneeshan, Michael P. Jones, Natasha Koloski, Gavin Callaghan, Mark Morrison, Gerald Holtmann
Summary: Oral vancomycin treatment in PSC-UC patients achieves clinical remission without development of vancomycin-resistant enterococci (VRE).
INDIAN JOURNAL OF GASTROENTEROLOGY
(2022)
Review
Oncology
Vaibhav Wadhwa, Nicole Patel, Dheera Grover, Faisal S. S. Ali, Nirav Thosani
Summary: Cancer in the gastrointestinal tract is a major global health issue, and early diagnosis and prompt management are crucial in preventing morbidity and mortality. Endoscopy has become the cornerstone in the diagnosis and management of gastrointestinal tract cancers.
CA-A CANCER JOURNAL FOR CLINICIANS
(2023)
Review
Gastroenterology & Hepatology
Michael P. Jones, Gerald Holtmann
Summary: Placebo responses provide insights into mechanisms beyond the intervention and affect the potential efficacy of new interventions in clinical trials. This mini-review discusses the systematic review and meta-analysis conducted by Bosman and colleagues on placebo response in functional dyspepsia clinical trials. It also explores potential mechanisms of placebo response in the context of brain-gut interaction disorders and extra-gastrointestinal disorders.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Adam I. I. Kaplan, Yoav Mazor, Gillian M. M. Prott, Carol Sequeira, Michael P. Jones, Allison Malcolm
Summary: Recent community-based studies have found that having multiple concurrent functional gastrointestinal disorders (FGIDs) is associated with increased somatization, worse quality of life (QoL), and greater healthcare utilization. However, the presence of multiple overlapping FGIDs specifically in chronic constipation and functional defecation disorders (FDD) has not been studied. This study investigated the prevalence and impact of additional nonconstipation FGIDs on constipation severity, anorectal physiology, anxiety and depression, and QoL in patients with chronic constipation and FDD.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Nick Goelen, Mike Jones, I-Hsuan Huang, Florenca Carbone, Pieter Janssen, Jan Tack
Summary: Gastroparesis and functional dyspepsia are disorders characterized by upper gastrointestinal symptoms and multifaceted etiologies. The association between symptom improvement and acceleration of gastric emptying (GE) by prokinetic agents is not clear. This meta-analysis aimed to provide a transparent update on the association between symptom improvement and GE acceleration in patients with gastroparesis.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2023)
Article
Veterinary Sciences
Leandro Abreu da Fonseca, Fabiano Montiani-Ferreira, Jeny Soto, Michael P. Jones, Nancy Zagaya, Carolyn Cray
Summary: This study compared agarose gel electrophoresis (AGE) and capillary zone electrophoresis (CZE) methods and determined reference intervals for CZE using plasma from bald eagles. The results showed that these two methods are not equivalent, and CZE demonstrated better resolution and reproducibility for protein fraction quantitation.
VETERINARY CLINICAL PATHOLOGY
(2023)
Review
Psychology, Clinical
Viviana M. Wuthrich, Dino Zagic, Sophie J. Dickson, Lauren F. McLellan, Jessamine T. -H. Chen, Michael P. Jones, Ronald M. Rapee
Summary: This systematic review and meta-analysis aimed to evaluate the effectiveness of psychological interventions for internalising disorders in young people in routine settings. The study found that psychotherapy led to small significant benefits for anxiety and depression in youth with internalising disorders. However, the results were limited by different reporters and follow-up.
CLINICAL CHILD AND FAMILY PSYCHOLOGY REVIEW
(2023)
Article
Psychiatry
Anastasia Ejova, Michael P. Jones, Alissa P. Beath, Sarah L. Mckerchar, Akiko Okifuji
Summary: There is evidence that people with both fibromyalgia and functional gastrointestinal disorders experience more severe psychological symptoms. Using Ecological Momentary Assessment (EMA), this study found that for individuals with fibromyalgia, accompanying GI symptoms lead to stronger bidirectional relationships between distress and bodily pain or fatigue.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Psychology, Mathematical
David McNaughton, Rhys Hope, Emily Gray, Freya Xavier, Alissa Beath, Michael Jones
Summary: This study combines haptic technology and electrical engineering to determine an individual's level of sensory attenuation to somatic stimuli. Results from analyzing 138 participants showed that the number of replications of the target forces can be reduced without compromising the estimate of sensory attenuation, the optimal time window for extracting the matched force is 2.5-3 s, and participants' performance during the task remains stable.
BEHAVIOR RESEARCH METHODS
(2023)