Linaclotide for Irritable Bowel Syndrome With Constipation: A 26-Week, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Efficacy and Safety

Linaclotide Improves Abdominal Pain and Bowel Habits in a Phase IIb Study of Patients With Irritable Bowel Syndrome With Constipation

(2010) Jeffrey M. Johnston et al.   GASTROENTEROLOGY

Measuring irritable bowel syndrome patient-reported outcomes with an abdominal pain numeric rating scale

(2009) B. SPIEGEL et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

An Evidence-Based Position Statement on the Management of Irritable Bowel Syndrome

(2009)   AMERICAN JOURNAL OF GASTROENTEROLOGY

Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain

(2009) h. eutamene et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Predictors of Patient-Assessed Illness Severity in Irritable Bowel Syndrome

(2008) Brennan Spiegel et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Irritable Bowel Syndrome

(2008) Emeran A. Mayer   NEW ENGLAND JOURNAL OF MEDICINE

Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations

(2007) Robert H. Dworkin et al.   JOURNAL OF PAIN