Article
Oncology
Shuang Yang, Jiang Bian, Thomas J. George, Karen Daily, Dongyu Zhang, Dejana Braithwaite, Yi Guo
Summary: The study found that women with mild or severe cognitive impairment were less likely to have undergone mammogram screening for breast cancer compared to those without cognitive impairment. Similarly, men with mild or severe cognitive impairment were less likely to have had a recent colonoscopy for colorectal cancer compared to those without cognitive impairment. Further research is needed to understand the factors contributing to these differences in cancer screening utilization among individuals with cognitive impairment.
Review
Gastroenterology & Hepatology
Nauzer Forbes, Robert J. Hilsden, Myriam Martel, Yibing Ruan, Catherine Dube, Alaa Rostom, Risa Shorr, Charles Menard, Darren R. Brenner, Alan N. Barkun, Steven J. Heitman
Summary: This systematic review revealed a consistent trend between delayed colonoscopy after a positive FIT and worse CRC-related outcomes, indicating that colonoscopy should not be delayed beyond 9 months.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Xuechen Chen, Feng Guo, Michael Hoffmeister, Jenny Chang-Claude, Hermann Brenner
Summary: Regular use of NSAIDs is associated with greatly reduced CRC risk regardless of individual genetic profile. Additionally, the effect of NSAID use is equivalent to having a 32 percentiles lower PRS, indicating a consistent relative risk reduction across all polygenic risk groups.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2021)
Article
Oncology
Suryun Kim, Dong Hoon Lee, Edward L. Giovannucci, NaNa Keum
Summary: Weight cycling refers to repeated intentional weight loss followed by unintentional weight gain. A study found that moderate weight cycling is associated with a reduced risk of colorectal cancer independent of BMI. Further research is needed to validate these findings and explore potential biological mechanisms.
BRITISH JOURNAL OF CANCER
(2023)
Article
Medicine, General & Internal
Marko Mandic, Fatemeh Safizadeh, Tobias Niedermaier, Michael Hoffmeister, Hermann Brenner
Summary: In this population-based case-control study conducted in Germany, overweight and obesity were found to be associated with an increased risk of colorectal cancer (CRC), taking into account substantial prediagnostic weight loss. The study also revealed a positive association between BMI, overweight, obesity, and a 5-unit increase in BMI measured 8 to 10 years before diagnosis, and a negative association between weight loss and CRC risk.
Article
Surgery
Joceline V. Vu, Kyle H. Sheetz, Ana C. De Roo, Tadd Hiatt, Samantha Hendren
Summary: A study found that there is substantial variation in the rate of colectomy for benign polyps in the United States, suggesting potential overuse of surgery for benign polyps in some regions.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Elisabeth Waldmann, Andreas A. Kammerlander, Irina Gessl, Daniela Penz, Barbara Majcher, Anna Hinterberger, Michael Bretthauer, Michael H. Trauner, Monika Ferlitsch
Summary: The study found that high-quality colonoscopy is associated with a lower risk of CRC death, with the impact of ADR being strongest for individuals with high-risk adenomas.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Medicine, General & Internal
Gregory Goshgarian, Camille Sorourdi, Folasade P. May, Sitaram Vangala, Sarah Meshkat, Lily Roh, Maria A. Han, Daniel M. Croymans
Summary: This study aimed to assess whether the use of an electronic patient portal primer message increases the completion rate of CRC screening in a mailed FIT outreach program. The results showed that adding an electronic primer message in the program significantly improved the screening completion rate and reduced the time to screening completion.
Article
Surgery
Roupen Djinbachian, Marie-Lyssa Lafontaine, Talia Dufault, Edgard Medawar, Michel Boivin, Mickael Bouin, Daniel von Renteln
Summary: This study aimed to evaluate the rate of synchronous advanced neoplasia (S-AN) and synchronous CRC (S-CRC) in colonoscopies where serrated lesions (SL) were detected. The study included 1262 patients with 1649 SLs. The results showed that patients with SLs are at high-risk of S-AN and S-CRC, with SSPs >= 10 mm and SSP dysplasia being high-risk factors for S-AN.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Editorial Material
Oncology
David Lieberman
Summary: There is solid evidence supporting the effectiveness of colorectal cancer screening in reducing incidence and mortality. Guidelines suggest screening for individuals between 45 to 75 years old, but there is uncertainty regarding the benefits for those above 75 years old. Dalmat et al. found that individuals who had a negative colonoscopy more than 10 years prior to reaching 76 to 85 years old had a lower risk of colorectal cancer and may not benefit from further screening. It is important to consider the study population did not include individuals with a family history of colon cancer or high-risk adenomas.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Medicine, General & Internal
Willemijn de Klaver, Pieter H. A. Wisse, Francine van Wifferen, Linda J. W. Bosch, Connie R. Jimenez, Rene W. M. van der Hulst, Remond J. A. Fijneman, Ernst J. Kuipers, Marjolein J. E. Greuter, Beatriz Carvalho, Manon C. W. Spaander, Evelien Dekker, Veerle M. H. Coupe, Meike de Wit, Gerrit A. Meijer
Summary: In this study, the multitarget FIT (mtFIT) showed improved diagnostic accuracy in detecting advanced neoplasia compared to FIT, particularly in detecting advanced adenomas. Early health technology assessment indicated that mtFIT-based screening could be cost-effective.
ANNALS OF INTERNAL MEDICINE
(2021)
Review
Endocrinology & Metabolism
Leandro Kasuki, Bernardo Maia, Monica R. Gadelha
Summary: Acromegaly, caused by excessive secretion of GH and IGF-I, is associated with an increased risk of colorectal cancer (CRC), although the exact mechanism is not fully understood. GH and IGF-I may influence the tumor microenvironment in the colon through promoting angiogenesis, cell proliferation, mutation risk, and inhibiting tumor-suppressor genes and apoptosis. However, there is controversy regarding the incidence and mortality of CRC in acromegaly. Nonetheless, guidelines recommend colonoscopic screening and surveillance for acromegaly patients, although the best timing for this remains uncertain.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Oncology
Jing Zhao, Yun Zhu, Meizhi Du, Yu Wang, Jillian Vallis, Patrick S. Parfrey, John R. Mclaughlin, Xiuying Qi, Peizhong Peter Wang
Summary: High dietary fiber intake is associated with improved survival among colorectal cancer patients, reducing the risk of all-cause mortality and CRC-specific mortality.
Article
Gastroenterology & Hepatology
Rebecca J. Birch, Nicholas Burr, Venkataraman Subramanian, Jim P. Tiernan, Mark A. Hull, Paul Finan, Azmina Rose, Matthew Rutter, Roland Valori, Amy Downing, Eva J. A. Morris
Summary: This study investigated the epidemiology and outcomes of inflammatory bowel disease-associated colorectal cancer (IBD-CRC). It found that IBD patients have a higher risk of developing CRC, are diagnosed at a younger age, and have worse outcomes compared to sporadic CRC. Further research is needed to understand the reasons behind these differences and inform screening, surveillance, and treatment strategies for this high-risk group.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Medicine, General & Internal
Joanne E. Schottinger, Christopher D. Jensen, Nirupa R. Ghai, Jessica Chubak, Jeffrey K. Lee, Aruna Kamineni, Ethan A. Halm, Celette Sugg-Skinner, Natalia Udaltsova, Wei K. Zhao, Rebecca A. Ziebell, Richard Contreras, Eric J. Kim, Bruce H. Fireman, Charles P. Quesenberry, Douglas A. Corley
Summary: This retrospective cohort study conducted in 3 large integrated health care systems found that physicians with higher adenoma detection rates were significantly associated with lower risks of postcolonoscopy colorectal cancer.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Endocrinology & Metabolism
L. C. Rosella, M. Lebenbaum, T. Fitzpatrick, D. O'Reilly, J. Wang, G. L. Booth, T. A. Stukel, W. P. Wodchis
Article
Health Care Sciences & Services
Marian J. Vermeulen, Astrid Guttmann, Therese A. Stukel, Ashif Kachra, Marco L. A. Sivilotti, Brian H. Rowe, Jonathan Dreyer, Robert Bell, Michael Schull
BMJ QUALITY & SAFETY
(2016)
Article
Emergency Medicine
Marian J. Vermeulen, Therese A. Stukel, Andrew S. Boozary, Astrid Guttmann, Michael J. Schull
ANNALS OF EMERGENCY MEDICINE
(2016)
Article
Medicine, General & Internal
Andrew Cheung, Therese A. Stukel, David A. Alter, Richard H. Glazier, Vicki Ling, Xuesong Wang, Baiju R. Shah
ANNALS OF INTERNAL MEDICINE
(2017)
Article
Surgery
Atiqa Malik, Chaim M. Bell, Therese A. Stukel, David R. Urbach
CANADIAN JOURNAL OF SURGERY
(2016)
Article
Medicine, General & Internal
Kevin L. Schwartz, Jeffrey C. Kwong, Shelley L. Deeks, Michael A. Campitelli, Frances B. Jamieson, Alex Marchand-Austin, Therese A. Stukel, Laura Rosella, Nick Daneman, Shelly Bolotin, Steven J. Drews, Heather Rilkoff, Natasha S. Crowcroft
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2016)
Article
Endocrinology & Metabolism
Rayzel Shulman, Therese A. Stukel, Fiona A. Miller, Alice Newman, Denis Daneman, Astrid Guttmann
PEDIATRIC DIABETES
(2017)
Article
Cardiac & Cardiovascular Systems
Cynthia A. Jackevicius, Jack V. Tu, Harlan M. Krumholz, Peter C. Austin, Joseph S. Ross, Therese A. Stukel, Maria Koh, Alice Chong, Dennis T. Ko
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2016)
Article
Medicine, General & Internal
Christopher J. Yarnell, Longdi Fu, Doug Manuel, Peter Tanuseputro, Therese Stukel, Ruxandra Pinto, Damon C. Scales, Andreas Laupacis, Robert A. Fowler
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2017)
Article
Medicine, General & Internal
Natasha Ruth Saunders, Michael Lebenbaum, Therese A. Stukel, Hong Lu, Marcelo L. Urquia, Paul Kurdyak, Astrid Guttmann
Article
Geriatrics & Gerontology
Natasha E. Lane, Walter P. Wodchis, Cynthia M. Boyd, Therese A. Stukel
Article
Health Policy & Services
Paul Kurdyak, Simone Natalie Vigod, Alice Newman, Vasily Giannakeas, Benoit H. Mulsant, Therese Stukel
PSYCHIATRIC SERVICES
(2018)
Article
Rheumatology
Peter Cram, Bruce E. Landon, John Matelski, Vicki Ling, Therese A. Stukel, J. Michael Paterson, Rajiv Gandhi, Gillian A. Hawker, Bheeshma Ravi
ARTHRITIS & RHEUMATOLOGY
(2018)
Article
Respiratory System
Laveena Munshi, Hayley B. Gershengorn, Eddy Fan, Hannah Wunsch, Niall D. Ferguson, Therese A. Stukel, Gordon D. Rubenfeld
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2017)
Article
Endocrinology & Metabolism
Rayzel Shulman, Therese A. Stukel, Fiona A. Miller, Alice Newman, Denis Daneman, Jonathan D. Wasserman, Astrid Guttmann
BMJ OPEN DIABETES RESEARCH & CARE
(2016)