Article
Gastroenterology & Hepatology
Yutaka Saito, Shiro Oka, Naoto Tamai, Toyoki Kudo, Nobutoshi Kuniyoshi, Tatsuya Shirakura, Yoshio Omae, Yukihiro Hamahata, Takehiro Arai, Shinji Tanaka, Noriya Uedo, Seiji Shimizu, Masakatsu Fukuzawa, Toshio Uraoka, Shiori Ichinose, Haruhiko Ogata, Kiyonori Kobayashi, Shoichi Saito, Hisao Tajiri
Summary: The study results suggest that the oral sulfate solution protocols are noninferior to polyethylene glycol plus ascorbate for bowel cleansing. The occurrence of adverse reactions was significantly lower in the oral sulfate solution same-day dose group compared to the polyethylene glycol plus ascorbate group, while there was no significant difference in adverse reactions between the oral sulfate solution split-dose group and the polyethylene glycol plus ascorbate group.
DIGESTIVE ENDOSCOPY
(2021)
Article
Medicine, General & Internal
Jae Hyun Kim, Yong Eun Park, Tae Oh Kim, Jongha Park, Gyu Man Oh, Won Moon, Seun Ja Park
Summary: This study compared the efficacy and safety of OST and PEG for colonoscopy bowel preparation, showing that the OST group had better BBPS and bubble scores, as well as higher satisfaction, regardless of age. Those under 65 in the OST group had a higher rate of completing the dose within 2 hours compared to the PEG group. Adverse events were not different between the two groups.
Article
Gastroenterology & Hepatology
Lorenzo Fuccio, Leonardo Frazzoni, Cristiano Spada, Alessandro Mussetto, Carlo Fabbri, Mauro Manno, Giovanni Aragona, Rocco Maurizio Zagari, Emanuele Rondonotti, Gianpiero Manes, Pietro Occhipinti, Sergio Cadoni, Franco Bazzoli, Cesare Hassan, Franco Radaelli
Summary: In a prospective observational study among inpatients, factors affecting inadequate colon cleansing were identified. A model to identify patients with inadequate preparation was derived and validated, and an app for clinicians was developed.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Seong Ran Jeon, Soo-Kyung Park, Dong-Hoon Yang, Jae Myung Cha
Summary: This study compared the efficacy, tolerability, and safety of mini-OST and conventional OST. The results showed that there were no significant differences in preparation efficacy, satisfaction, and tolerability between the two groups. The first bowel movement occurred earlier in the mini-OST group. The occurrence of adverse events was comparable between the two groups. In conclusion, mini-OST showed similar efficacy, tolerability, and safety compared to conventional OST.
JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Michael S. L. Sey, Daniel Von Renteln, Richard Sultanian, Cassandra McDonald, Mickael Bouin, Nilesh Chande, Amindeep Sandhu, Brian Yan, Myriam Martel, Alan Barkun
Summary: This study compared the efficacy, tolerability, and safety of two regimens for bowel preparation after failed attempts. The results showed that split-dose 4 L-PEG with 15 mg bisacodyl, along with dietary restrictions, had similar efficacy as a higher-volume preparation. This method should be considered for patients who previously failed bowel preparation.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Medicine, General & Internal
Antonio Z. Gimeno-Garcia, Federica Benitez-Zafra, David Nicolas-Perez, Manuel Hernandez-Guerra
Summary: This manuscript comprehensively reviews the current strategies employed to optimize bowel cleansing, with a specific focus on patients with elevated risks for inadequate bowel preparation. Additionally, the prospective role of AI in this context is thoroughly examined. The authors point out that dealing with hard-to-prepare patients remains a challenge and that rescue strategies based on AI are promising but lack sufficient evidence. Therefore, a combination of strategies should be performed to ensure proper bowel cleansing.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
Ki Young Lim, Kyeong Ok Kim, Eun Young Kim, Yoo Jin Lee, Byung Ik Jang, Sung Kook Kim, Chang Heon Yang
Summary: This study aimed to evaluate the safety and efficacy of 1 L polyethylene glycol (PEG) plus ascorbic acid (Asc) in older adults by comparing it with oral sulfate solution (OSS). The results showed that the successful bowel preparation rate was over 90% in both 1 L PEG/Asc and OSS groups, without severe adverse effects and significant changes in renal function. This indicates that 1 L PEG/Asc, as a new low-dose preparation regimen for colonoscopy in older adults, is as effective and safe as OSS.
KOREAN JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Alan N. Barkun, Myriam Martel, Ian L. Epstein, Pierre Halle, Robert J. Hilsden, Paul D. James, Alaa Rostom, Michael Sey, Harminder Singh, Richard Sultanian, Jennifer J. Telford, Daniel von Renteln
Summary: This study compared the efficacy of high-volume polyethylene glycol (PEG) with low-volume PEG with bisacodyl split-dosing regimens. The results showed that low-volume PEG was noninferior to high-volume PEG in providing adequate bowel preparation. In addition, low-volume PEG resulted in fewer symptoms, greater willingness to repeat the preparation, and better tolerability.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Vincenzo Occhipinti, Paola Soriani, Sara Vavassori, Maria Laura Annunziata, Francesco Bagolini, Flaminia Cavallaro, Pavlos Lagoussis, Valentina Milani, Emanuele Rondonotti, Luisa Spina, Maurizio Vecchi, Luca Pastorelli, Gian Eugenio Tontini
Summary: Bowel preparation is crucial for colonoscopy completeness and lesions detection. Identification of preparation-specific risk factors for inadequate bowel preparation may lead to a personalized prescription of cleansing products to refine patients' tolerance and improve endoscopic outcomes.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Helmut Neumann, Melissa Latorre, Tim Zimmerman, Gabriel Lang, Jason Samarasena, Seth Gross, Bhaumik Brahmbhatt, Haleh Pazwash, Vladimir Kushnir
Summary: The Pure-Vu System effectively improved bowel preparation quality in hospitalized subjects undergoing colonoscopy, with significant improvements seen in the left colon, transverse colon, and right colon segments. The clarity of the last bowel movement may be a useful indicator in predicting poor bowel preparation. Further large-scale studies are needed to evaluate the clinical outcomes and significance of these findings.
BMC GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Francesco Maione, Michele Manigrasso, Marco Milone, Nicola Gennarelli, Rosa Maione, Grazia Cantore, Alessia Chini, Giovanni Domenico De Palma
Summary: This study investigated the impact of atmospheric temperature on bowel cleansing during colonoscopy. The results showed that high temperature (>25 degrees C) significantly affected the colon cleansing. In addition, factors such as gender, diabetes, previous pelvic surgery, use of certain medications, adoption of specific solutions, patient compliance, age, body mass index, and education levels were associated with inadequate colon cleansing.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2023)
Article
Gastroenterology & Hepatology
Ja Seol Koo, Jeong-Sik Byeon, Bo-In Lee, Sung-Ae Jung, Tae Il Kim, Yoon Tae Jeen
Summary: The study compared the efficacy of TJP-008 and 2LPEG for colon cleansing during colonoscopy and found that TJP-008 was non-inferior to 2LPEG in overall bowel cleansing success, with TJP-008 showing superior performance in high-quality cleansing in the right colon.
Article
Gastroenterology & Hepatology
Carmen Tse, Alan Barkun, Myriam Martel, Zoann Nugent, Ian Epstein, Michael Sey, Sultanian Richard, Daniel von Renteln, Harminder Singh
Summary: In this study, we investigated sleep disturbances, bowel movement kinetics, and travel experience with different bowel preparation regimens for colonoscopy. The results showed that patients who underwent colonoscopy in the morning experienced the most awakenings during the night when using a 4-L single-dose PEG the day before, and the greatest reduction in sleep hours when using a 4-L split-dose PEG. There were no significant differences between groups in terms of urgent bowel movements, fecal incontinence episodes, or travel interruptions.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Naohisa Yoshida, Yoshikazu Inagaki, Daisuke Hasegawa, Reo Kobayashi, Yuri Tomita, Hikaru Hashimoto, Ryohei Hirose, Osamu Dohi, Ken Inoue, Yasutaka Morimoto, Yutaka Inada, Takaaki Murakami, Yoshito Itoh
Summary: This study analyzed the efficacy of a same-day regimen of 480 ml oral sulfate solution (OSS) in improving insufficient bowel preparation (BP) caused by high-concentrated polyethylene glycol (H-PEG).
GASTROENTEROLOGY RESEARCH AND PRACTICE
(2023)
Article
Gastroenterology & Hepatology
Xin Gao, Qiugui Bian, Wenqin Ding, Haisheng Qian, Wenjie Li, Guoxin Zhang, Xuan Li
Summary: This study aimed to explore the effectiveness of walking exercise and intestinal cleansing interval in bowel preparation before colonoscopy. The results showed that taking 10,000 steps of walking exercise during the intestinal preparation and taking polyethylene glycol (PEG) 5.12 hours prior to the procedure were effective in cleaning the colon and improving the accuracy of colonoscopy.
DIGESTIVE DISEASES AND SCIENCES
(2023)