Article
Nutrition & Dietetics
Gavriela Feketea, John Lakoumentas, George N. Konstantinou, Nikolaos Douladiris, Nikolaos G. Papadopoulos, Maria Petrodimopoulou, Ioannis Tasios, Mina Valianatou, Vasiliki Vourga, Emilia Vassilopoulou
Summary: This retrospective observational study explored the role of maternal diet during pregnancy and breastfeeding in tolerance acquisition in infantile food protein-induced allergic proctocolitis (FPIAP). The study found that higher maternal education and consumption of salt and goat/sheep cheese during pregnancy, and consumption of olive oil during breastfeeding were associated with earlier resolution of FPIAP.
Article
Allergy
Aysen Uncuoglu, Metin Aydogan, Isil Eser Simsek, Mujde Tuba Cogurlu, Kubra Ucak, Hazal Cansu Acar
Summary: This study investigated the symptom spectrum, resolution time, triggering foods, and risk factors for multiple food allergies (MFA) in food protein-induced allergic proctocolitis (FPIAP). The results showed that infants who presented with visible blood in stool before 2 months of age had a tendency to transient bleeding. Mucus in stool was the last symptom to disappear, and concurrent atopic dermatitis (AD) suggested a high probability of MFA in FPIAP.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Microbiology
Victoria M. Martin, Yamini V. Virkud, Ehud Dahan, Hannah L. Seay, Dvir Itzkovits, Hera Vlamakis, Ramnik Xavier, Wayne G. Shreffler, Qian Yuan, Moran Yassour
Summary: This study is the first to identify differences in the infant gut microbiome in children who develop food protein-induced allergic proctocolitis (FPIAP), some even before they develop symptoms. These findings provide a foundation for further mechanistic investigation into the pathogenesis of FPIAP and subsequent food allergic diseases in childhood.
Article
Nutrition & Dietetics
Emilia Vassilopoulou, Gavriela Feketea, George N. Konstantinou, Dimitris Zekakos Xypolias, Mina Valianatou, Maria Petrodimopoulou, Vasiliki Vourga, Ioannis Tasios, Nikolaos G. Papadopoulos
Summary: This study explored the association between food protein-induced allergic proctocolitis (FPIAP) and maternal diet during pregnancy and breastfeeding in Greek infants. The results showed that components of a maternal Mediterranean Diet may protect against FPIAP when traditional cooking methods are adopted and fish, fruit, and whole wheat products are consumed frequently during pregnancy and breastfeeding.
FRONTIERS IN NUTRITION
(2022)
Article
Allergy
Nur Senocak, Aysegul Ertugrul, Serap Ozmen, Ilknur Bostanci
Summary: The study found that the symptoms of FPIAP appeared earlier in premature infants and later in infants using formula. The use of an amino acid-based formula and the presence of diarrhea were associated with the development of tolerance.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Pediatrics
Cheong-Jun Moon, Tae Hee Kwon, Hyun-Seung Lee
Summary: Peripheral blood eosinophilia is commonly seen in various medical conditions related to allergic, infectious, and inflammatory processes. In neonates, especially preterm infants, eosinophilia may increase the risk of thrombotic events, including rare complications like portal vein thrombosis. In cases of prolonged eosinophilia in premature neonates, consideration should be given to the potential occurrence of conditions like food protein-induced allergic proctocolitis and evaluation for neonatal thrombosis.
Article
Gastroenterology & Hepatology
Philipp Wurm, Laura Stampfer, Theresa Greimel, Eva Leitner, Ellen L. Zechner, Sebastian Bauchinger, Almuthe C. Hauer, Gregor Gorkiewicz, Christoph Hoegenauer, K. Martin Hoffmann
Summary: This study investigated infants with suspected food protein induced proctocolitis (sFPIP) and found that there is a significant difference in gut microbiota composition between sFPIP infants and healthy infants, indicating a dysbiosis phenomenon. Diagnostic dietary intervention (DDI) can restore gut microbiota composition in sFPIP infants to that of healthy infants. Therefore, hematochezia in sFPIP patients may be triggered by gut microbiota dysbiosis.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2023)
Article
Nutrition & Dietetics
Sonia L. Robinson, Mercedes Mora-Plazas, Henry Oliveros, Constanza Marin, Betsy Lozoff, Eduardo Villamor
Summary: Adherence to an animal protein dietary pattern in middle childhood was associated with lower externalizing behavior problems in adolescent boys in a Latin American context, while there were no associations with other dietary patterns or internalizing problems.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Yansong Zhang, Siyuan Lin, Jingyu Peng, Xiaojuan Liang, Qi Yang, Xue Bai, Yajuan Li, Jinhua Li, Wei Dong, Yue Wang, Ying Huang, Yumeng Pei, Jiabao Guo, Wanni Zhao, Zhe Zhang, Min Liu, Alan Jian Zhu
Summary: The study reveals that dietary essential amino acids can improve NAFLD by inducing polyubiquitination of Plin2, a lipid droplet-stabilizing protein. Leucine and isoleucine can activate the Ubr1 enzyme to target Plin2 for degradation. Additionally, activation of Ubr1 family proteins can significantly improve obesity-induced and high-fat diet-induced hepatic steatosis in mice.
Article
Nutrition & Dietetics
Outi Sirkka, Maria Fleischmann, Marieke Abrahamse-Berkeveld, Jutka Halberstadt, Margreet R. Olthof, Jacob C. Seidell, Eva Corpeleijn
Summary: Limited and inconsistent evidence exists on the associations between dietary patterns and overweight during childhood. The study found that a dietary pattern high in energy-dense and low-fiber ultra-processed foods at age 3 is associated with overweight and a high BMI-SDS later in childhood. Although high adherence to both 'minimally processed foods' and 'ultra-processed foods' patterns was related to BMI-SDS, a stronger association was observed for the 'ultra-processed foods' pattern.
Article
Environmental Sciences
Shravanthi M. Seshasayee, Sheryl L. Rifas-Shiman, Jorge E. Chavarro, Jenny L. Carwile, Pi-I D. Lin, Antonia M. Calafat, Sharon K. Sagiv, Emily Oken, Abby F. Fleisch
Summary: This study examined the association between children's diet and PFAS, finding that intake of ice cream and soda was associated with higher plasma concentrations of specific PFAS. A dietary pattern consisting of primarily packaged foods and fish was identified to be correlated with higher PFAS concentrations. Further investigation is needed to inform measures to modify childhood PFAS exposure.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Nutrition & Dietetics
Anh N. Nguyen, Astrid W. B. van Langeveld, Jeanne H. M. de Vries, M. Arfan Ikram, Cees de Graaf, Monica Mars, Trudy Voortman
Summary: The study evaluated dietary taste patterns in early childhood and found that at age 2, taste patterns were more varied and intense, similar to patterns observed in Dutch adults. Factors such as maternal socioeconomic characteristics and feeding practices were associated with dietary taste patterns in young children.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Allergy
Semiha Bahceci, Pinar Kuyum Toz, Figen Celebi Celik, Demet Can
Summary: The aim of this study was to investigate the long-term prognosis of food protein-induced allergic proctocolitis (FPIAP) patients and the risk of developing both allergic and gastrointestinal diseases. The results showed that the prevalence of comorbid allergic disease was significantly higher in the FPIAP group compared to the control group. However, there was no significant difference between the two groups in terms of functional gastrointestinal disorders, eosinophilic gastrointestinal diseases, and inflammatory bowel disease. In conclusion, patients with FPIAP may develop allergic and gastrointestinal diseases in the long term.
ALLERGOLOGIA ET IMMUNOPATHOLOGIA
(2023)
Review
Nutrition & Dietetics
Ana Rita Pereira, Andreia Oliveira
Summary: Most dietary interventions for childhood obesity prevention focus on person-based educational approaches and show inconsistent effects on changing children's body mass index. Few interventions address environmental changes and macro policy changes, and their sustainability over time remains unclear.
Review
Allergy
Nicklas Brustad, Klaus Bonnelykke, Bo Chawes
Summary: Asthma, the most common chronic disease in childhood, has seen an increase in prevalence along with changing dietary habits in the Western world. A Westernized diet high in processed food and fat has replaced the Mediterranean diet high in fruit, vegetable, and fish intake. This change has led to a decreased intake of important antioxidants and micronutrients, potentially affecting the inflammatory and immunoregulatory properties of the body. While observational studies have investigated the association between dietary intake and asthma, there is a need for well-conducted randomized controlled trials to examine the primary preventive effect of micronutrient supplementations. The Global Initiative for Asthma (GINA) currently does not include maternal dietary changes or supplementations during pregnancy in their recommendations for primary prevention, but there is growing evidence suggesting the potential protective effects of specific dietary patterns and micronutrient supplements.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)