Review
Gastroenterology & Hepatology
Marco Spadaccini, Edoardo Vespa, Viveksandeep Thoguluva Chandrasekar, Madhav Desai, Harsh K. Patel, Roberta Maselli, Alessandro Fugazza, Silvia Carrara, Andrea Anderloni, Gianluca Franchellucci, Alessandro De Marco, Cesare Hassan, Pradeep Bhandari, Prateek Sharma, Alessandro Repici
Summary: This paper summarizes the current evidence, recent research advancements, and future perspectives regarding advanced imaging technology and artificial intelligence (AI) in Barrett's esophagus (BE). It stresses the importance of comprehensive endoscopic assessment and computer-aided diagnosis in improving diagnostic outcomes.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Elissa M. Ozanne, Elisabeth R. Silver, Sameer D. Saini, Joel H. Rubenstein, Iris Lansdorp-Vogelaar, Nicole Bowers, Sarah Xinhui Tan, John M. Inadomi, Chin Hur
Summary: Physicians' recommendations for BE surveillance cessation vary based on patient age, comorbidities, and BE length, with age showing the most significant variation in decisions. It appears that age and comorbidities influence BE surveillance cessation decisions, but with differences among clinicians. Clear guidelines balancing the risks and benefits of BE surveillance cessation are needed.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Edward H. Tsoi, Puneet Mahindra, Georgina Cameron, Richard Williams, Richard Norris, Paul Desmond, Spiro Raftopoulos, Darren Pavey, Arti Rattan, Luke F. Hourigan, Richard Lee, Michael J. Bourke, Naaz Sidhu, Rajvinder Singh, Andrew Chan, Sudarshan Krishnamurthi, Andrew C. F. Taylor
Summary: This study aimed to determine the proportion of prevalent HGD or EAC detected in Barrett's esophagus (BE) patients referred from the community with a recent diagnosis of low-grade dysplasia (LGD). The results showed that BERU assessment endoscopy identified more visible lesions than community referral endoscopy and identified HGD or EAC in 27% of patients referred from the community with a recent diagnosis of LGD. Reported progression rates from LGD to HGD or EAC may be overestimated.
GASTROINTESTINAL ENDOSCOPY
(2021)
Review
Oncology
Lu Zhang, Binyu Sun, Xi Zhou, QiongQiong Wei, Sicheng Liang, Gang Luo, Tao Li, Muhan Lu
Summary: This article briefly describes the etiology and clinical significance of intestinal metaplasia in Barrett's esophagus, as well as its impact on diagnosis, monitoring, and treatment according to different guidelines. The basis for endoscopic diagnosis and identification techniques of goblet cells in Barrett's esophagus are explored, along with current treatment methods related to the condition.
FRONTIERS IN ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hsin-Yu Fang, Stefan Stangl, Sabrina Marcazzan, Marcos J. Braz Carvalho, Theresa Baumeister, Akanksha Anand, Julia Strangmann, Julia Slotta Huspenina, Timothy C. Wang, Roland M. Schmid, Marcus Feith, Helmut Friess, Vasilis Ntziachristos, Gabriele Multhoff, Dimitris Gorpas, Michael Quante
Summary: This study evaluated the use of a highly specific Hsp70-specific contrast agent in guided fluorescence molecular endoscopy biopsy, showing promising potential to improve tumor surveillance in BE patients, especially in cases with dysplasia and EAC.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Gastroenterology & Hepatology
Joel H. Rubenstein, Jennifer A. Burns, Maria E. Arasim, Elizabeth M. Firsht, Matthew Harbrecht, Marilla Widerquist, Richard R. Evans, John M. Inadomi, Joy W. Chang, William D. Hazelton, Chin Hur, Jacob E. Kurlander, Francesca Lim, Georg Luebeck, Peter W. Macdonald, Chanakyaram A. Reddy, Sameer D. Saini, Sarah Xinhui Tan, Akbar K. Waljee, Iris Lansdorp-Vogelaar
Summary: This study aimed to estimate the yield of repeat esophagogastroduodenoscopy (EGD) performed at prolonged intervals after a normal index EGD. The results showed that a longer duration between EGD was associated with a greater odds of a new diagnosis of Barrett's esophagus, esophageal adenocarcinoma, or esophagogastric junction adenocarcinoma, especially among younger individuals.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Materials Science, Multidisciplinary
Sara Fresard, Katherine L. Anderson, Dvir Avnon-Klein, Sarah Pangburn, Steven Cranford
Summary: Scientific research is most valuable when it can be shared and digested by any kind of audience, but the skills required to disseminate information and gain trust are often not taught to scientists. CUNYSciCom, a student organization founded by two biology doctoral students, aims to help graduate students at the City University of New York improve their science communication skills and engage with the public through various events.
Article
Environmental Sciences
Hao Chen, James M. Samet, Haiyan Tong, Aiman Abzhanova, Ana G. Rappold, Steven E. Prince
Summary: This study finds that disposable facemasks can maintain a high level of filtration efficiency even after extended wearing, and laundering the masks may reduce their effectiveness. It suggests that reusing disposable masks is a safe means of reducing plastic waste.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Review
Medicine, General & Internal
Francesco Maione, Alessia Chini, Rosa Maione, Michele Manigrasso, Alessandra Marello, Gianluca Cassese, Nicola Gennarelli, Marco Milone, Giovanni Domenico De Palma
Summary: Barrett's Esophagus is a common condition associated with chronic gastroesophageal reflux disease and has a higher risk of developing esophageal adenocarcinoma. Low and high-grade dysplasia precede neoplastic transformation in this condition. The evaluation of low-grade dysplastic esophageal mucosa is still controversial, but endoscopic surveillance and minimally invasive endoscopic treatments such as endoscopic mucosal resection and radiofrequency ablation are available options. Cryotherapy ablation and argon plasma coagulation are novel endoscopic treatments with high eradication rates and fewer complications and post-procedural pain.
Article
Gastroenterology & Hepatology
Maarten R. Struyvenberg, Albert J. de Groof, Joost van der Putten, Fons van der Sommen, Francisco Baldaque-Silva, Masami Omae, Roos Pouw, Raf Bisschops, Michael Vieth, Erik J. Schoon, Wouter L. Curvers, Peter H. de With, Jacques J. Bergman
Summary: The research demonstrated the feasibility of a deep-learning CAD system for tissue characterization of NBI zoom imagery in Barrett's esophagus, achieving promising diagnostic accuracy in predicting the presence/absence of Barrett's neoplasia.
GASTROINTESTINAL ENDOSCOPY
(2021)
Review
Psychology, Multidisciplinary
Erika Branchini, Elena Capitani, Roberto Burro, Ugo Savardi, Ivana Bianchi
Summary: This paper highlights the importance of opposites as an organizing principle in human thinking, showing evidence from various studies that thinking in opposites can improve reasoning skills and problem-solving abilities. By prompting individuals to think in opposites, performance in tasks can be enhanced, leading to possible benefits that warrant further systematic testing and research.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Surgery
Olivia Hershorn, Jason Park, Harminder Singh, Kathleen Clouston, Ashley Vergis, Ramzi M. Helewa
Summary: A study conducted in a high-volume Canadian tertiary centre found that 29% of colorectal surgery patients required repeat preoperative endoscopy. Factors such as male sex, lesions located in the left colon, rectosigmoid, and rectum were associated with increased odds of undergoing repeat preoperative endoscopy. Tattooing suspicious lesions significantly reduced the likelihood of repeat preoperative endoscopy.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Biochemistry & Molecular Biology
Maria Manuela Estevinho, Rolando Pinho, Joao Carlos Silva, Joao Correia, Pedro Mesquita, Teresa Freitas
Summary: Hybrid argon plasma coagulation (hAPC) is a novel technique that combines conventional argon plasma coagulation and waterjet submucosal expansion. This meta-analysis evaluated the efficacy and safety of hAPC in Barret's esophagus (BE) ablation and as an adjunct to colonic endoscopic mucosal resection (EMR). The results showed high percentages of endoscopic and histologic remission after hAPC for BE, along with low rates of adverse events and recurrence. Similarly, hAPC-assisted EMR had low rates of adverse events and recurrence. Further trials comparing hAPC with standard strategies are needed to support its use for these indications.
Article
Gastroenterology & Hepatology
Sarmed S. Sami, James P. Moriarty, Jordan K. Rosedahl, Bijan J. Borah, David A. Katzka, Kenneth K. Wang, John B. Kisiel, Krish Ragunath, Joel H. Rubenstein, Prasad G. Iyer
Summary: In GERD-independent scenarios, most non-sEGD BE screening tests were cost-effective, with swallowable esophageal cell collection devices with biomarkers being the optimal choice. However, exhaled volatile organic compounds had the highest ICERs in all scenarios.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Claire A. Beveridge, Chetan Mittal, V. Raman Muthusamy, Amit Rastogi, Vladimir Kushnir, Mariah Wood, Sachin Wani, Srinadh Komanduri
Summary: This study aimed to assess the rate of visible lesion (VL) detection by academic and community endoscopists using high-definition white-light endoscopy (HD-WLE) and narrow-band imaging (NBI). Participants identified VLs using HD-WLE and NBI, and the results showed that 28% and 31% of VLs were not identified using HD-WLE and NBI respectively. The study also found that the rate of VL detection was associated with the endoscopist's experience and the number of surveillance endoscopies performed each month.
GASTROINTESTINAL ENDOSCOPY
(2023)