期刊
AMERICAN JOURNAL OF EPIDEMIOLOGY
卷 172, 期 8, 页码 890-899出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/aje/kwq274
关键词
body mass index; cohort studies; depression; social class; suicide; attempted
资金
- United Kingdom Medical Research Council
- Chief Scientist Office at the Scottish Government Health Directorates
- Biotechnology and Biological Sciences Research Council
- Engineering and Physical Sciences Research Council
- Economic and Social Research Council
- Medical Research Council
- University of Edinburgh
- Academy of Finland
- BUPA Foundation, United Kingdom
- National Heart, Lung, and Blood Institute [R01HL036310-20A2]
- National Institute on Aging [R01AG034454]
- US National Institutes of Health
- Swedish Research Council
- Labour Market Insurance, Ltd.
- Swedish Council for Working Life and Social Research
- MRC [MC_U130059821] Funding Source: UKRI
- Medical Research Council [MC_U130059821] Funding Source: researchfish
Associations between body mass index (BMI) and attempted (nonfatal) suicide have recently been reported. However, the few existing studies are relatively small in scale, the majority cross-sectional, and results contradictory. The authors have explored BMI-attempted suicide associations in a large cohort of 1,133,019 Swedish men born between 1950 and 1976, with BMI measured in early adulthood. During a mean follow-up of 23.9 years, a total of 18,277 (1.6%) men had at least 1 hospital admission for attempted suicide. After adjustment for confounding factors, there was a stepwise, linear decrease in attempted suicide with increasing BMI across the full BMI range (per standard deviation increase in BMI, hazard ratio = 0.93, 95% confidence interval: 0.91, 0.94). Analyses excluding men with depression at baseline were essentially identical to those based on the complete cohort. In men free from depression at baseline, controlling for subsequent depression slightly attenuated the raised risk of attempted suicide, particularly in lower weight men. This study suggests that lower weight men have an increased risk of attempted suicide and that associations may extend into the normal BMI range.
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