Article
Nutrition & Dietetics
Melissa K. Blake, Ruixuan Ma, Erika Viana Cardenas, Parisa Varanloo, Yaray Agosto, Carolina Velasquez, Katheryn A. Espina, Joanne Palenzuela, Sarah E. Messiah, Ruby A. Natale
Summary: This study investigated the association between age at solid food initiation and obesity prevalence in preschool-aged children, taking into account disability status, ethnicity, gestational age, and birth weight. The findings revealed no significant difference in obesity prevalence based on age at solid food introduction. Children with disabilities and preterm births had significantly lower odds of being obese, while Hispanic children and those with higher birth weights were more likely to be obese.
Article
Medicine, General & Internal
Louisa W. Holaday, Destiny G. Tolliver, Tiana Moore, Keitra Thompson, Emily A. Wang
Summary: This study explores the association between neighborhood incarceration rates and adverse birth outcomes in New York City. The findings suggest that neighborhoods with higher incarceration rates have higher rates of preterm birth, low birth weight, and other adverse birth outcomes. This association is particularly significant for Black residents, indicating that mass incarceration may contribute to racial disparities in birth outcomes.
Article
Pediatrics
Fermin Garcia-Munoz Rodrigo, Jorge Fabres, Jose L. Tapia, Ivonne D'Apremont, Laura San Feliciano, Carlos Zozaya Nieto, Josep Figueras-Aloy, Gonzalo Mariani, Gabriel Musante, Fernando Silvera, Jaime Zegarra, Maximo Vento
Summary: This study aimed to analyze perinatal variables and interventions associated with survival and survival without major morbidity in VLBW infants, comparing two large networks. Results revealed the network of origin as a significant factor influencing outcomes, in addition to certain birth characteristics. Significant variability in outcomes was found within each network.
Article
Multidisciplinary Sciences
Liza Darrous, Ninon Mounier, Zoltan Kutalik
Summary: Mendelian Randomization (MR) is a popular method for estimating the causal effects of risk factors on complex human traits, but existing MR methods suffer from limitations in utilizing genome-wide markers and sensitivity to heritable confounders. The newly proposed LHC-MR method outperforms existing MR methods, demonstrating superior performance in a wide range of simulation settings and uncovering new mechanisms and causal effects.
NATURE COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Yuchen Li, Arvid Sjolander, Huan Song, Sven Cnattingius, Fang Fang, Qian Yang, Lorena Fernandez de la Cruz, David Mataix-Cols, Gustaf Brander, Jiong Li, Wei Zhang, Katja Fall, Brian M. D'Onofrio, Catarina Almqvist, Paul Lichtenstein, Unnur A. Valdimarsdottir, Donghao Lu
Summary: This study investigated the effects of parental and perinatal factors on the risk of stress-related disorders. The findings suggest that most of the observed associations between these factors and the risk of stress-related disorders are driven by shared familial environment or genetics. The study highlights the importance of family designs in epidemiological studies on the etiology of psychiatric disorders.
MOLECULAR PSYCHIATRY
(2022)
Article
Infectious Diseases
Kanokwan Aeimcharnbanchong
Summary: This study aimed to determine the incidence rate and associated factors of early onset sepsis (EOS) in neonates with 35 weeks or more of gestational age at PCMC in order to develop effective prevention and treatment strategies for reducing neonatal mortality. The study found a low incidence rate of culture positive EOS, which was significantly associated with prolonged rupture of membrane and low birth weight. On the other hand, a lower rate of EOS was significantly associated with normal Apgar score at 5 minutes after birth. Efforts to identify these factors early and provide effective resuscitation for neonates may help reduce and prevent neonatal morbidity and mortality.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Environmental Sciences
Jiawen Liao, Yang Liu, Kyle Steenland, Ajay Pillarisetti, Lisa M. Thompson, Sagnik Dey, Kalpana Balakrishnan, Thomas Clasen
Summary: A study conducted in India shows an association between exposure to PM2.5 during the in utero and post-delivery periods and child survival. This study highlights the need for measures to reduce ambient air pollution levels, especially during pregnancy and early life stages, in India and other countries where guideline values are exceeded.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2022)
Article
Pediatrics
Tianchan Lyu, Yibo Tao, Wei Hua, Liling Li, Yunfei Tang, Yumei Jin, Yan Wang, Yuelan Ma, Futing Ji, Yalan Dou, Yun Cao, Xiao-Jing Hu
Summary: The study found that most VLBWIs in the Yangtze River Delta region were infants with birth weights between 750g and 1500g, with premature rupture of membranes being the main cause of preterm birth. In terms of care practices, the rates of umbilical vein catheterization and peripherally inserted central catheter were 25.0% and 64.4% respectively. The study also showed that the mortality rate of preterm infants was 3.4%, with main complications including BPD, PDA, ROP, NEC and sepsis.
Article
Medicine, General & Internal
Yulika Yoshida-Montezuma, Branavan Sivapathasundaram, Hilary K. Brown, Charles Keown-Stoneman, Russell J. de Souza, Teresa To, Cornelia M. Borkhoff, Catherine S. Birken, Jonathon L. Maguire, Laura N. Anderson
Summary: Children born late preterm and moderately preterm have higher cardiometabolic risk, suggesting that screening and early-life interventions for these children may prevent cardiometabolic outcomes.
Review
Nutrition & Dietetics
Siti Helmyati, Maria Wigati, Muhammad Hafizh Hariawan, Erri Larene Safika, Mira Dewi, Cindra Tri Yuniar, Trias Mahmudiono
Summary: This study examined the association between maternal health behaviors and neonatal outcomes among the Indonesian population through a meta-analysis. The results showed that pregnant women with incomplete antenatal care had a higher risk of low birth weight and neonatal mortality, and those who were passively exposed to smoking were also at higher risk of low birth weight.
Article
Oncology
Claire E. E. Thomas, Jennifer J. J. Adibi, Allison L. L. Kuipers, Brenda Diergaarde, Hung N. N. Luu, Aizhen Jin, Woon-Puay Koh, Yu-Tang Gao, Jennifer Adams-Haduch, Renwei Wang, Anna Lokshin, Jaideep Behari, Jian-Min Yuan
Summary: CD137 is associated with increased risk of hepatocellular carcinoma (HCC) and may serve as a long-term risk marker for HCC development.
BRITISH JOURNAL OF CANCER
(2023)
Article
Multidisciplinary Sciences
Jennifer Dunne, Gizachew A. Tessema, Amanuel T. Gebremedhin, Gavin Pereira
Summary: The aim of this study is to estimate the magnitude of bias resulting from left truncated data in the association between advanced maternal age and stillbirth. The simulation results showed minimal marginal downward bias, particularly for women aged 40 + years.
SCIENTIFIC REPORTS
(2022)
Article
Pediatrics
Jing Li, Jing Zhang, Qingfei Hao, Ziyun Shen, Yanna Du, Haoming Chen, Xiuyong Cheng
Summary: This study explored the association between the time from the first extubation to reintubation and the occurrence of moderate-to-severe bronchopulmonary dysplasia (BPD) or death in very low birth weight infants. The findings showed that reintubation within 72 hours after the initial extubation was independently associated with an increased likelihood of moderate-to-severe BPD/death and death, while reintubation within the first 48 hours post-extubation posed the greatest risk.
FRONTIERS IN PEDIATRICS
(2022)
Article
Public, Environmental & Occupational Health
Alicia R. Riley, Daniel Collin, Jacob M. Grumbach, Jacqueline M. Torres, Rita Hamad
Summary: The extreme right-left partisanship in the current US context affects state policies, with left-leaning state policy orientation being associated with lower odds of adverse birth outcomes, especially for infants born in the US and White mothers. However, the association between left-leaning state policy orientation and lower odds of adverse birth outcomes may be explained by stable characteristics of states.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2021)
Article
Multidisciplinary Sciences
Barbara Almeida Soares Dias, Katrini Guidolini Martinelli, Luiz Carlos de Abreu, Edson Theodoro dos Santos-Neto
Summary: The objective of this study was to analyze the factors associated with preventable infant mortality in Espirito Santo, Brazil. Data were collected from records of infant deaths classified as preventable and non-preventable. Logistic regression was used to investigate the factors associated with preventable deaths. The results showed that approximately 73% and 76% of the deaths were preventable according to different methods. Preterm birth, postneonatal death, and birth weight between 3000 and above 4000 g were found to be associated with higher chances of preventable infant deaths. The quality of care offered during the prenatal, prepartum, and childbirth periods was identified as a significant factor for preventable infant deaths.
Article
Pediatrics
Laura L. Oakley, Annette K. Regan, Deshayne B. Fell, Sarah Spruin, Inger Johanne Bakken, Jeffrey C. Kwong, Gavin Pereira, Natasha Nassar, Kari M. Aaberg, Allen J. Wilcox, Siri E. Haberg
Summary: This study found that maternal influenza infection during pregnancy may increase the risk of childhood seizures, particularly febrile seizures. Children exposed to influenza infection in utero had a higher risk of seizures in the second and third trimester of pregnancy.
ARCHIVES OF DISEASE IN CHILDHOOD
(2022)
Article
Nutrition & Dietetics
Jonathan Groot, Tanja G. Petersen, Pal Suren, Anne Lise Brantsoeter, Peter Uldall, Torben Martinussen, Charlotta Granstrom, Sjurdur F. Olsen, Allen J. Wilcox, Katrine Strandberg-Larsen
Summary: The study found that periconceptional folate supplementation was not associated with cerebral palsy (CP), while supplementation during gestational weeks 9-12 was linked to a reduced risk of CP. Midpregnancy supplementation or dietary folate alone did not show a significant association with CP. Strong inverse associations were observed with low gross motor function impairment, suggesting potential benefits of folate intake during gestational weeks 9-12 for reducing the risk of CP.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Obstetrics & Gynecology
Shruthi Mahalingaiah, Victoria Fruh, Erika Rodriguez, Sai Charan Konanki, Jukka-Pekka Onnela, Alexis de Figueiredo Veiga, Genevieve Lyons, Rowana Ahmed, Huichu Li, Nicola Gallagher, Anne Marie Z. Jukic, Kelly K. Ferguson, Donna D. Baird, Allen J. Wilcox, Christine L. Curry, Sanaa Suharwardy, Tyler Fischer-Colbrie, Gracee Agrawal, Brent A. Coull, Russ Hauser, Michelle A. Williams
Summary: The Apple Women's Health Study aims to gain a better understanding of the relationship between menstrual cycles, health, and behavior. The first 10,000 participants in this study were diverse in demographic characteristics and all used Apple iPhones.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Lise A. Arge, Siri E. Haberg, Allen J. Wilcox, Oyvind Naess, Olga Basso, Maria C. Magnus
Summary: History of miscarriage is associated with decreased fecundability, while subfertility is linked to higher risk of miscarriage in subsequent pregnancies.
HUMAN REPRODUCTION
(2022)
Article
Public, Environmental & Occupational Health
Ellen O. Carlsen, Quaker Harmon, Maria C. Magnus, Helle M. Meltzer, Iris Erlund, Lars C. Stene, Siri E. Haberg, Allen J. Wilcox
Summary: This study found that among women without a history of diabetes, higher HbA1c levels at 18 weeks of pregnancy were associated with important perinatal outcomes, including birth weight, large-for-gestational age, preterm delivery, and preeclampsia.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Tarannum Behlim, Olga Basso, Tracey Bushnik, Michael S. Kramer, Jay S. Kaufman, Seungmi Yang
Summary: This study examines the independent associations of maternal and paternal nativity and length of residence with birthweight for gestational age in infants in Canada. The results suggest that parental nativity and length of residence may affect birthweight outcomes.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2022)
Article
Multidisciplinary Sciences
Jenna Nobles, Lindsay Cannon, Allen J. Wilcox
Summary: US state legislatures have proposed laws to ban abortion once the earliest embryonic electrical activity is detectable, affecting specific population subgroups who may face difficulties in detecting pregnancy early due to irregular menstrual cycles and common health conditions. Individual physiological limitations may impact the ability to detect pregnancy before fetal cardiac activity.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Letter
Public, Environmental & Occupational Health
Allen Wilcox, Olga Basso
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Olga Basso, Maria C. Magnus, Lise A. Arge, Siri E. Haberg
Summary: The study suggests that daughters born to young mothers or older fathers may have slightly lower fecundability, highlighting the potential impact of parental age on female fertility.
HUMAN REPRODUCTION
(2022)
Article
Public, Environmental & Occupational Health
Maria C. Magnus, Alexandra Havdahl, Allen J. Wilcox, Alice Goisis
Summary: Parental time-to-pregnancy is modestly but robustly associated with neurodevelopmental delays and difficulties in offspring, with no additional impact of assisted reproductive technologies.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Ana K. Rosen Vollmar, Clarice R. Weinberg, Donna D. Baird, Allen J. Wilcox, Antonia M. Calafat, Nicole C. Deziel, Caroline H. Johnson, Anne Marie Z. Jukic
Summary: Urinary phenol concentrations of 2,5-dichlorophenol were associated with an increased odds of early pregnancy loss, while higher concentrations of butylparaben and triclosan were associated with an increase in fecundability. This study is the first to investigate the associations between phenol exposure and fecundability and early pregnancy loss using repeated pooled measures, providing important insights for future research on reproductive health.
HUMAN REPRODUCTION
(2023)
Article
Public, Environmental & Occupational Health
Allen J. Wilcox, Olga Basso
Summary: Reduced birthweight is a marker of pathologies that impair growth and decrease survival. Fetal growth restriction affects a small percentage of births but has a high neonatal mortality risk. The prevalence of these pathological births has remained stable over time, while neonatal mortality has declined. Public health strategies should focus on factors unrelated to birthweight that have contributed to the reductions in neonatal mortality.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Olga Basso, Gabriel D. Shapiro, Robert Gagnon, Robyn Tamblyn, Robert W. Platt
Summary: This study found that ovulatory disorders were consistently associated with a higher prevalence of congenital malformations (including severe malformations) among live births, regardless of mode of conception.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2023)