期刊
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
卷 138, 期 4, 页码 506-510出版社
OXFORD UNIV PRESS INC
DOI: 10.1309/AJCPGSNL9VDVNJMX
关键词
Invasive EEG monitoring; Medically intractable epilepsy
类别
资金
- American Epilepsy Society
- US Department of Defense
- UCB, Brussels, Belgium
- Pfizer, New York, NY
Invasive electroencephalography (EEG) monitoring is often needed for presurgical evaluation in patients with medically intractable epilepsy (MIE). This study retrospectively reviews the pathologic changes associated with EEG monitoring. Two hundred twenty-six patients who underwent invasive monitoring (53.5% males; mean age, 29.8 years) and 55 controls without EEG monitoring (52.7% males; mean age, 25.6 years) were evaluated. Median length of invasive EEG monitoring was 7.0 days. Compared with controls, patients who were monitored had more pathologic changes related to invasive EEG monitoring (n = 171 [75.7%] vs n = 12 121.8%1; P < .0001) including meningeal or parenchymal chronic inflammation (n = 128 [56.4%] vs n = 11120.4%], P < .0001) and acute contusion and/or acute/subacute infarct (n = 110 [48.5%] vs n = 0; P < .0001). Histologic evidence of pathologic changes typically associated with invasive monitoring and/or craniotomy occurred in 76% of our patients with invasive monitoring compared with 19% in patients without prior invasive EEG evaluation. The most common pathologic changes related to invasive monitoring were chronic inflammation and contusion/infarct.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据