Article
Medicine, General & Internal
Diego Dominguez-Balmaseda, Jose Angel Del-Blanco-Muniz, Angel Gonzalez-de-la-Flor, Guillermo Garcia-Perez-de-Sevilla
Summary: The study compared dietary fatty acid intake between patients with chronic TTH and healthy participants, finding higher intake of saturated fatty acids (SFAs) in TTH patients. Additionally, omega-6 fatty acid intake was associated with more intense headache episodes in the TTH group.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Food Science & Technology
Ismael Rodriguez-Gonzalez, Beatriz Diaz-Reinoso, Herminia Dominguez
Summary: Marine organisms are valuable sources of long-chain omega-3 polyunsaturated fatty acids, which are increasingly in demand for their health benefits. Seaweeds have a low lipid content, but their high PUFA fraction and low omega-6:omega-3 ratio make them an alternative source. Concentrated lipid extracts provide a practical method without significantly changing dietary habits. The extraction technology plays a key role in the production of seaweed extracts, and the choice of solvent and operational conditions can also extract other lipophilic components, resulting in a final product with interesting biological properties. Utilizing the remaining algal solids as a source of additional nutritional and bioactive compounds is essential for achieving a sustainable process.
FOOD AND BIOPROCESS TECHNOLOGY
(2022)
Article
Agronomy
Supriyanto Supriyanto, Zulhamsyah Imran, Rhomi Ardiansyah, Brian Auliyai, Aditya Pratama, Faustinus Kadha
Summary: Sacha Inchi, a Peruvian seed with high levels of unsaturated fatty acids, has been studied under different cultivation conditions in order to determine its adaptability and effects on seed production and oil quality. The results showed that seed productivity was highest in open area cultivation, while oil yield was highest in mixed cultures. The content of Omega-3 was highest in the agroforestry condition, while Omega-6 and Omega-9 were highest in the open area.
Article
Nutrition & Dietetics
Woojung Yang, Jong Hun Lee, Jae-woo Lee, Yonghwan Kim, Ye-Seul Kim, Hyo-Sun You, Hee-Taik Kang
Summary: The study found an association between omega 3FA ratio and subclinical inflammation in men, with a decrease in prevalence of subclinical inflammation in males as the omega 3FA ratio increased. However, there was no significant difference in prevalence among quartile groups in females.
Article
Food Science & Technology
Saranporn Wongpattananukul, Uarna Nungarlee, Arnakorn Ruangprach, Suwaibah Sulong, Promluck Sanporkha, Sirichai Adisakwattana, Sathaporn Ngamukote
Summary: The use of Sacha inchi oil (IPO) as a substitute for animal fat in meat products can improve the nutritional properties by reducing saturated fat content and omega-6/omega-3 ratio while increasing omega-3 fatty acid content. Moreover, it can enhance the emulsion stability and texture properties of sausages. However, the addition of higher amounts of IPO may increase TBARS value during refrigerated storage.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Geir Bjorklund, Maryam Dadar, Monica Daniela Dosa, Salvatore Chirumbolo, Joeri J. Pen
Summary: Various nutrients with antioxidant properties are being investigated for their potential impact on diseases like cancer, including their effects on prostaglandins. The omega6/omega-3 PUFA ratio is being studied for its antioxidative effects in countering pathophysiological mechanisms. This research focuses specifically on the bone microenvironment and its implications for health, particularly in the context of malignant bone metastasis.
CURRENT MEDICINAL CHEMISTRY
(2021)
Article
Nutrition & Dietetics
Akinori Hara, Hiromasa Tsujiguchi, Keita Suzuki, Masaharu Nakamura, Masaru Okada, Jiaye Zhao, Chie Takazawa, Fumihiko Suzuki, Tomoko Kasahara, Yukari Shimizu, Hirohito Tsuboi, Takayuki Kannon, Atsushi Tajima, Toshinari Takamura, Hiroyuki Nakamura
Summary: The study explored the relationship between dietary intake of fatty acids and chronic kidney disease (CKD) in Japanese people. It found that low intake of omega-3 and high omega-6-to-omega-3 ratio were associated with CKD in participants with diabetes, but not in those without diabetes.
Article
Nutrition & Dietetics
Jae-Woo Lee, Yonghwan Kim, Taisun Hyun, Seunghye Song, Woojung Yang, Ye-Seul Kim, Hyo-Sun You, Young-Chang Chang, Seung-Ho Shin, Hee-Taik Kang
Summary: The study found that incorporating a low omega-6/omega-3 fatty acid ratio home meal replacement (HMR) can improve cardiometabolic parameters and reduce the prevalence of metabolic syndrome in obese individuals. This randomized crossover trial demonstrated significant reductions in BMI, weight, and MetS prevalence after a 4-week intervention with the HMR.
Article
Nutrition & Dietetics
Sebastian Andone, Lenard Farczadi, Silvia Imre, Zoltan Bajko, Anca Motataianu, Smaranda Maier, Laura Barcutean, Rodica Balasa
Summary: Stroke prevention is crucial and can be achieved by addressing risk factors, particularly modifiable lifestyle factors. Our study investigated the relationship between ischemic-stroke risk factors and fatty acids in 274 patients using a prospective observational study. We found that age, sex, smoking, atrial fibrillation, dyslipidemia, and previous stroke history were directly related to fatty acids. Smoking had the most significant negative impact, while dyslipidemia and atrial fibrillation had a positive correlation, particularly in female patients and those with recurrent strokes. Better management of risk factors could improve fatty-acid profiles and the balance of Omega-3 and Omega-6 in ischemic stroke patients.
Article
Nutrition & Dietetics
Adam Lepczynski, Malgorzata Ozgo, Katarzyna Michalek, Alicja Dratwa-Chalupnik, Marta Grabowska, Agnieszka Herosimczyk, Kamila P. Liput, Ewa Polawska, Andrzej Kram, Mariusz Pierzchala
Summary: The study found that different high-fat diets had an impact on the structure and protein expression of the murine heart, with SFA-rich diets leading to severe cardiac hypertrophy and fibrosis, while diets rich in n-3 PUFA resulted in less pronounced changes.
Article
Biochemistry & Molecular Biology
Adnan Kanbar, Julia Beisel, Meylin Terrel Gutierrez, Simone Graeff-Hoenninger, Peter Nick
Summary: This study compared the accumulation of polyunsaturated fatty acids between four genotypes of A. caudatus and a commercial variety of A. hypochondriacus under a temperate environment. The A. caudatus genotypes flowered later and yielded fewer grains compared to the Mexican hybrid. Kiwicha oil had a higher content of unsaturated fatty acids, especially linoleic acid and a-linolenic acid. The study also found differences in gene expression related to fatty acid metabolism and cold stress between the genotypes, suggesting that the climatic conditions of domestication contribute to the variation in fatty acid content.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Domenico Sergi, Juana Maria Sanz, Stefano Lazzer, Gloria Brombo, Giovanni Zuliani, Gianni Biolo, Bostjan Simunic, Rado Pisot, Edoardo Dalla Nora, Angelina Passaro
Summary: Dietary lipids play a crucial role in modulating metabolic inflammation, and interleukin 18 (IL-18) has been consistently linked to obesity and insulin resistance. This study aimed to assess if the quality of lipid intake affects IL-18 plasma levels and its implications on insulin resistance. The study confirmed that IL-18 is positively correlated with insulin resistance, and individuals with higher HOMA-IR levels displayed elevated IL-18 levels. The quality of dietary lipids, particularly the ratio between different fatty acids and the intake of omega-3, showed a negative correlation with IL-18 levels.
Article
Chemistry, Applied
Barbara Mazurek, Urszula Ryszko, Dorota Kostrzewa, Mariusz Chmiel, Malgorzata Kondracka
Summary: Berry seeds are a rich source of high-quality oil, containing valuable compounds such as polyunsaturated fatty acids, and have been gaining importance as a potential source of nutrients for the food, cosmetic, or pharmaceutical industries. Supercritical carbon dioxide extraction of seeds results in oil extracts with high unsaturated fatty acid content and a good n-3/n-6 fatty acid ratio, making them valuable products for various industries.
Article
Food Science & Technology
Asavari Joshi, Mahabaleshwar Hegde, Anand Zanwar
Summary: The study aimed to develop an oil blend with improved omega-6 to omega-3 fatty acid ratio and good stability. The results showed that the blending improved the fatty acid ratio and stability, potentially leading to better health benefits.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2022)
Article
Nutrition & Dietetics
Supal Mehta, Lara Ruth Dugas, Candice Choo-Kang, Pascal Bovet, Terrence Forrester, Kweku Bedu-Addo, Estelle Vicki Lambert, Jacob Plange-Rhule, Walter Riesen, Wolfgang Korte, Amy Luke
Summary: This study examined the association between intake of long-chain omega-3 PUFAs and cardiometabolic risk in four African-origin populations, finding that low EPA + DHA intake was associated with increased risks of cardiometabolic disease, inflammation, and obesity. Additionally, a high ratio of AA/EPA + DHA was also linked to higher risks of these health conditions. The findings support the beneficial role of monounsaturated fatty acids in reducing cardiometabolic risk.
Article
Nutrition & Dietetics
Carol L. Cheatham, Kelly Will Sheppard
Article
Nutrition & Dietetics
Kelly W. Sheppard, Carol L. Cheatham
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2017)
Article
Nutrition & Dietetics
Sarah A. Keim, Barbara Gracious, Kelly M. Boone, Mark A. Klebanoff, Lynette K. Rogers, Joseph Rausch, Daniel L. Coury, Kelly W. Sheppard, Jesse Husk, Dale A. Rhoda
JOURNAL OF NUTRITION
(2018)
Article
Biochemistry & Molecular Biology
Kelly W. Sheppard, Carol L. Cheatham
LIPIDS IN HEALTH AND DISEASE
(2018)
Article
Pediatrics
Sarah A. Keim, Kelly M. Boone, Mark A. Klebanoff, Abigail Norris Turner, Joseph Rausch, Mary Ann Nelin, Lynette K. Rogers, Keith Owen Yeates, Leif Nelin, Kelly W. Sheppard
Article
Obstetrics & Gynecology
Jessica Londeree Saleska, Kelly Sheppard, Abigail Norris Turner, Kelly M. Boone, Sarah A. Keim
AMERICAN JOURNAL OF PERINATOLOGY
(2020)
Article
Nutrition & Dietetics
Taniqua T. Ingol, Rui Li, Kelly M. Boone, Joseph Rausch, Mark A. Klebanoff, Abigail Norris Turner, Keith O. Yeates, Mary Ann Nelin, Kelly W. Sheppard, Sarah A. Keim
JOURNAL OF NUTRITION
(2019)
Article
Pediatrics
Sarah A. Keim, Jacqueline A. Sullivan, Kelly Sheppard, Katie Smith, Taniqua Ingol, Kelly M. Boone, Antonio Malloy-McCoy, Reena Oza-Frank
Summary: The study found that exclusive breastfeeding was associated with certain aspects of executive function, while feeding expressed milk was not clearly related; there was no significant impact on global cognitive ability; weak associations were observed with eating behaviors for some feeding practices.
JOURNAL OF PEDIATRICS
(2021)
Article
Psychology, Clinical
Bharathi J. Zvara, Kelly W. Sheppard, Martha Cox
JOURNAL OF FAMILY PSYCHOLOGY
(2018)
Article
Health Policy & Services
Melanie Livet, Mary Yannayon, Kelly Sheppard, Kelly Kocher, James Upright, Janey McMillen
ADMINISTRATION AND POLICY IN MENTAL HEALTH AND MENTAL HEALTH SERVICES RESEARCH
(2018)
Article
Psychology, Developmental
Kelly W. Sheppard, Carol L. Cheatham
JOURNAL OF COGNITION AND DEVELOPMENT
(2017)
Article
Psychology, Developmental
Kelly W. Sheppard, Kelly M. Boone, Barbara Gracious, Mark A. Klebanoff, Lynette K. Rogers, Joseph Rausch, Christopher Bartlett, Daniel L. Coury, Sarah A. Keim
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2017)
Article
Neurosciences
Karla Klein Murdock, Carolyn Greene, Sue K. Adams, William Hartmann, Sally Bittinger, Kelly Will
ANXIETY STRESS AND COPING
(2010)