Article
Surgery
Siren Nymo, Oda Borresen Skjolsvold, Marthe Aukan, Graham Finlayson, Hallvard Graeslie, Ronald Marvik, Bard Kulseng, Jorunn Sandvik, Catia Martins
Summary: Suboptimal weight loss after bariatric surgery is associated with dysfunctional eating behaviors, increased preference and reward for high-fat food, and increased hedonic hunger.
Article
Multidisciplinary Sciences
Yeshong Park, Young Suk Park, Sangjun Lee, So Hyun Kang, Eunju Lee, Sang-Hoon Ahn, Yun-Suhk Suh, Do Joong Park, Hyung-Ho Kim
Summary: The study compared the short-term outcomes of single-port, reduced-port, and conventional laparoscopic sleeve gastrectomy, suggesting that single-port and reduced-port approaches could be alternative choices for selected patients. Although there was a slight difference in remission of dyslipidemia, this difference disappeared after matching. Further studies are necessary to establish standardized guidelines for single-port sleeve gastrectomy.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
Panagiotis Lainas, Radwan Kassir, Marine Benois, Joseph Derienne, Tarek Debs, Maissa Safieddine, Jean Gugenheim, Ibrahim Dagher, Imed Ben Amor
Summary: The study compared conventional laparoscopic surgery and robotic-assisted Roux-en-Y gastric bypass surgery, finding that the robotic approach had shorter operative times, similar weight loss outcomes, and equivalent safety measures. Further well-designed randomized studies are needed to draw more conclusive results on the benefits of robotic surgery for this procedure.
JOURNAL OF ROBOTIC SURGERY
(2021)
Article
Surgery
Brigitte Anderson, Tingting Zhan, Luke Swaszek, Caroline Sanicola, Neil King, Aurora Pryor, Konstantinos Spaniolas, Renee Tholey, Francesco Palazzo, Alec Beekley, Talar Tatarian
Summary: This study evaluated the incidence of marginal ulcers (MUs) after primary and secondary Roux-en-Y Gastric Bypass (RYGB). The results showed that patients who underwent conversion of Sleeve Gastrectomy to RYGB had a higher incidence of MUs compared to those who had primary RYGB or Gastric Banding to RYGB. Furthermore, the time to MU development was significantly shorter in patients who underwent conversion surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Medicine, General & Internal
Janine Maria Makaronidis, Andrea Pucci, Marco Adamo, Andrew Jenkinson, Mohamed Elkalaawy, Rachel Louise Batterham
Summary: This study investigated the factors influencing hedonic hunger and found that Roux-en-Y gastric bypass and sleeve gastrectomy can alleviate hedonic hunger, helping to maintain weight loss. Changes in hedonic hunger were correlated with post-operative weight loss, indicating that PFS may play a predictive role in the outcomes of SG and RYGB surgeries.
INTERNAL AND EMERGENCY MEDICINE
(2022)
Article
Surgery
Sophia M-T Schmitz, Patrick H. Alizai, Andreas Kroh, Sandra Schipper, Jonathan F. Brozat, Andreas Plamper, Ulf P. Neumann, Karl Rheinwalt, Tom F. Ulmer
Summary: A retrospective study comparing outcomes of super-super-obese (SSO) patients undergoing one anastomosis gastric bypass (OAGB) and laparoscopic sleeve gastrectomy (LSG) showed that OAGB resulted in greater weight loss, shorter procedure length, shorter hospital stay, and fewer severe complications than LSG. OAGB can be considered a safe and effective treatment modality for SSO patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Hematology
Else-Marie Bladbjerg, Charlotte R. Stolberg, Lene H. Mundbjerg, Bibi Gram, Yaseelan Palarasah, Claus B. Juhl, Johannes J. Sidelmann, Jorgen B. Gram
Summary: The contact system was affected 6 months after Roux-en-Y gastric bypass surgery. Absolute values of kallikrein generation before and after surgery correlated with contact system proteins, whereas changes after surgery associated with changes in C1-inh and metabolic variables.
THROMBOSIS RESEARCH
(2021)
Article
Nutrition & Dietetics
Beatriz de Azevedo Muner Ferreira, Danielle Cristina Fonseca, Priscila Sala, Juliana Tepedino Martins Alves, Ana Paula Aguiar Prudencio, Natasha Mendonca Machado, Mariane Marques, Samira Barcelos, Robson Kiyoshi Ishida, Ismael Francisco Mota Siqueira Guarda, Eduardo Guimaraes Hourneaux De Moura, Paulo Sakai, Marco Aurelio Sante, Raquel Susana Matos de Miranda Torrinhas, Dan Linetzky Waitzberg
Summary: This study aimed to assess whether Roux-en-Y gastric bypass (RYGB) affects the expression of genes related to intestinal folate metabolism as a mechanism contributing to postoperative deficiency. The results showed that RYGB altered the gene expression of intestinal folate metabolism, with decreased expression of folate transporters/receptors and increased expression of folate biosynthesis genes. In addition, reduced folate intake and plasma folate levels were observed. The findings suggest that impaired gene expression of intestinal folate metabolism may contribute to early systemic folate deficiency after RYGB.
Article
Nutrition & Dietetics
Sandra M. B. P. Moreira, Andre L. L. Bachi, Elias I. Jirjos, Carlos A. A. Malheiros, Sergio Vencio, Vera L. S. Alves, Alan R. T. Sousa, Lucenda A. Felipe, Eduardo A. Perez, Maria E. M. Lino, Shayra K. A. Souza, Juliana M. B. Santos, Miria C. Oliveira, Adriano L. Fonseca, Carlos H. M. Silva, Rodolfo P. Vieira, Giuseppe Insalaco, Wilson R. R. Freitas Junior, Luis V. F. Oliveira
Summary: Obesity is a significant public health problem that increases the risk of various health complications. Bariatric surgery, such as Roux-en-Y gastric bypass (RYGB), is an effective treatment for severe obesity and associated comorbidities. This study investigated the effects of RYGB on women with severe obesity with and without metabolic syndrome (MetS) by analyzing biochemical, glucose, and inflammatory parameters. The results showed significant improvements in weight, body mass index, glucose, cholesterol, and leptin levels, as well as an increase in adiponectin/leptin ratio after RYGB. These findings highlight the beneficial effects of weight loss induced by RYGB on metabolic and inflammatory parameters in women with severe obesity.
Article
Surgery
Christina E. E. Lundberg, Lena Bjorck, Martin Adiels, Jesper Lagergren, Annika Rosengren
Summary: The study aimed to assess the risks of myocardial infarction, ischemic stroke, and cardiovascular-related and all-cause mortality after Roux-en-Y gastric bypass (RYGB) for obesity. The results showed that RYGB patients had a reduced risk of myocardial infarction within the first 3 years of follow-up, but no significant difference in risk of ischemic stroke. Compared to nonobese population controls, RYGB patients had increased risks of ischemic stroke, cardiovascular-related mortality, and all-cause mortality.
Article
Nutrition & Dietetics
Damien Bergeat, Nicolas Coquery, Yentl Gautier, Sarah Clotaire, Emilie Vincent, Veronique Rome, Sylvie Guerin, Isabelle Le Huerou-Luron, Sophie Blat, Ronan Thibault, David Val-Laillet
Summary: This study investigated the long-term consequences of Roux-en-Y gastric bypass (RYGBP) surgery on brain mRNA expression, cecal microbiota, and plasma metabolites in obese Yucatan minipigs. The results demonstrated that RYGBP significantly affected the expression of brain genes, cecal microbiota, and plasma metabolites, which in turn influenced food reward, hedonic evaluation, and inhibitory control, all of which are crucial for the success of anti-obesity therapy and weight loss maintenance.
CLINICAL NUTRITION
(2023)
Article
Endocrinology & Metabolism
Saghi Sadoughi, Courtney Pasco, Gabby B. Joseph, Po-Hung Wu, Anne L. Schafer, Galateia J. Kazakia
Summary: This study found that patients undergoing RYGB surgery experienced significant increases in cortical porosity in the midcortical and periosteal layers of the tibia and radius at 12 months postoperatively, suggesting that the mechanism driving this increase is not primarily endosteal trabecularization.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Medicine, General & Internal
Chantal A. Boly, Margot Venhuizen, Nicole A. M. Dekker, Alexander B. A. Vonk, Christa Boer, Charissa E. van den Brom
Summary: Cardiac surgery with cardiopulmonary bypass impairs microcirculatory perfusion equally in metabolically healthy obese patients and lean patients, with recovery observed in both groups within three days post-surgery.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nutrition & Dietetics
Arun Prasath Lakshmanan, Sara Al Zaidan, Dhinoth Kumar Bangarusamy, Sahar Al-Shamari, Wahiba Elhag, Annalisa Terranegra
Summary: This study investigated the effects of dietary intake and gut microbial composition on modulating the risk of cardiovascular disease development in obese Qatari adults. The results showed differences in vitamin D intake, relative abundance of Ruminococcus and Bifidobacterium genera, metabolic levels between the CVD risk and no-risk groups.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Ulrich Dischinger, Tobias Heckel, Thorsten Bischler, Julia Hasinger, Malina Koenigsrainer, Angelika Schmitt-Boehrer, Christoph Otto, Martin Fassnacht, Florian Seyfried, Mohammed Khair Hankir
Summary: This study examined the effects of Roux-en-Y gastric bypass (RYGB) surgery and gut hormone-based treatments on hypothalamic gene expression and signaling pathways. While RYGB and body weight-matched treatments had significant impacts on hypothalamic gene expression and signaling pathways, the PYY3-36 + liraglutide treatment did not. Further investigation is needed to determine the long-term metabolic health implications of these findings.