Article
Gastroenterology & Hepatology
Hee-Kyung Joh, Dong Hoon Lee, Jinhee Hur, Katharina Nimptsch, Yoosoo Chang, Hyojee Joung, Xuehong Zhang, Leandro F. M. Rezende, Jung Eun Lee, Kimmie Ng, Chen Yuan, Fred K. Tabung, Jeffrey A. Meyerhardt, Andrew T. Chan, Tobias Pischon, Mingyang Song, Charles S. Fuchs, Walter C. Willett, Yin Cao, Shuji Ogino, Edward Giovannucci, Kana Wu
Summary: The study found that high intake of simple sugars and SSBs during adolescence was associated with an increased risk of conventional adenoma, especially rectal adenoma. However, sugar and SSB intake during adulthood was not linked to adenoma risk.
Article
Food Science & Technology
Hongzhen Du, Qian Liu, Qian Chen, Xiufang Xia, Ming Xu, Baohua Kong
Summary: The impact of different woodchips on HAAs contents and quality characteristics of smoked bacon was investigated. The results showed that beech and oak smoked bacon had lower HAAs contents compared to pear and apple smoked bacon. The smoking process promoted the formation of FAA in the smoked bacon. Woodchip types had no significant influence on certain quality characteristics of the bacon.
Article
Food Science & Technology
Zeynep Elbir, Elif Ekiz, Eyad Aoudeh, Emel Oz, Adem Savas, Charles Brennan, Charalampos Proestos, Mohammad Rizwan Khan, Tahra Elobeid, Margaret Brennan, Fatih Oz
Summary: This study investigated the impact of using different rates of chia seeds in meatballs on various factors such as water content, pH, lipid oxidation, cooking loss, and HAAs content. The results showed that chia seeds significantly affected water content, cooking loss, pH, and total HAAs content. However, no significant impact was observed on TBARS value. Cooking temperatures also had a significant effect on water content, cooking loss, and total HAAs content. The content of total HAAs increased with higher cooking temperatures.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Genetics & Heredity
Motoki Iwasaki, Shoichiro Tsugane
Summary: Heterocyclic aromatic amines (HAAs), formed by the reaction of creatine or creatinine, amino acids, and sugars in meat and fish cooked at high temperatures, have been linked to cancer risk, but specific dietary habits and cooking methods in different countries impact research outcomes. Studies in Japan found low HAAs intake, mainly from fish, associated with increased risks of colorectal adenoma and prostate cancer.
GENES AND ENVIRONMENT
(2021)
Article
Chemistry, Analytical
Lili Sun, Zejiang Wang, Juan Hou, Guozhen Fang, Jifeng Liu, Shuo Wang
Summary: Heterocyclic amines (HCA) are mutagenic factors in cooked meat products and pose a hazard to food safety. This study presents a new technique for detecting 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) using the molecular cavities of cucurbit[7]uril (CB[7]) for guest recognition. The method involves three steps: oxidation of regenerated cellulose (RC) membrane, trapping of PhIP molecules using amine-aldehyde conjugation chemistry, and quantification of PhIP through host-guest interaction with dansyl chloride-labelled CB[7] dye.
Article
Gastroenterology & Hepatology
Hanseul Kim, Marla Lipsyc-Sharf, Xiaoyu Zong, Xiaoyan Wang, Jinhee Hur, Mingyang Song, Molin Wang, Stephanie A. Smith-Warner, Charles Fuchs, Shuji Ogino, Kana Wu, Andrew T. Chan, Yin Cao, Kimmie Ng, Edward L. Giovannucci
Summary: The results of the study show that higher total vitamin D intake is associated with decreased risks of early-onset colorectal cancer (CRC) and precursors in women. The inverse association was more evident for dietary sources of vitamin D compared to supplemental vitamin D intake.
Article
Food Science & Technology
Idil Uzun, Fatih Oz
Summary: The study found that using basil in meatball production can reduce TBARS values, but the effect on HAA formation varies depending on the usage rate and cooking temperature.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2021)
Article
Food Science & Technology
Revsan Bulan, Fatih Oz
Summary: The study found that the addition of tarragon can completely inhibit the formation of HAAs in meatballs and reduce the TBARS value of the samples. Adding tarragon in meatball production could be recommended to improve product quality compared to the control group.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jia Shen, Yin Li, Meihui Xu, Fei Wu, Yanjie Jiang, Xiaohui Liu, Yang Ao, Qianru Lin, Pan Zhuang, Jingjing Jiao, Weifang Zheng, Yu Zhang
Summary: This study aimed to assess the association between egg intake and colorectal polyp prevalence. Through a food frequency questionnaire and electronic colonoscopy, it was found that high egg consumption was significantly correlated with a higher prevalence of colorectal polyps among the Chinese population at a high risk of CRC. However, this association disappeared after further adjustment for dietary cholesterol. Replacing egg intake with total dairy products was associated with a decrease in colorectal polyp prevalence.
Article
Chemistry, Multidisciplinary
Mei-Xin Lv, Shan Jiang, Chen Wang, Qi Dong, Feng-Ying Bai, Yong-Heng Xing
Summary: The development of fluorescent heterocyclic compounds bearing s-triazine and cyclotriphosphazene scaffolds for researching the structure-property relationship and high-efficiency amine sensing is still challenging. In this study, two polypodal aldehyde-based flexible organic compounds were prepared and two hydrogen-bonded organic frameworks were obtained. The fluorescence response of the compounds to aliphatic amine, especially ethylenediamine, indicated their potential application for ethylenediamine detection.
Article
Food Science & Technology
Hongzhen Du, Xiangao Li, Qiang Wang, Qian Liu, Qian Chen, Baohua Kong
Summary: The influence of using KCl to replace NaCl on the quality of bacon was investigated. The results showed that increasing the substitution rate led to changes in sensory characteristics and chemical composition of the bacon.
Article
Gastroenterology & Hepatology
Issei Hasegawa, Takeshi Yamamura, Hiroto Suzuki, Keiko Maeda, Tsunaki Sawada, Yasuyuki Mizutani, Eri Ishikawa, Takuya Ishikawa, Naomi Kakushima, Kazuhiro Furukawa, Eizaburo Ohno, Hiroki Kawashima, Masanao Nakamura, Mitsuhiro Fujishiro
Summary: The study found that while the ADR was similar between the LCI and WLI groups, the LCI group showed significantly lower AMR, especially for diminutive adenomas and nonpolypoid lesions. This suggests that LCI has an advantage in reducing adenoma miss rate.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Food Science & Technology
Hongzhen Du, Qiang Wang, Qian Liu, Qian Chen, Haotian Liu, Ming Xu, Baohua Kong
Summary: This study investigated the influence of different levels of NaCl on the HAA contents and quality characteristics of bacon. The results showed that reducing the NaCl concentration led to an increase in moisture, a(w) value, L* value, b* value, TBARS, and carbonyl content. Sensory evaluation revealed that increasing NaCl concentration significantly enhanced the saltiness of bacon. Higher NaCl concentrations resulted in a decreased total HAA content in fried bacon. Additionally, nonpolar HAA contents in bacon were higher than polar HAA contents, and salt concentration mainly affected the nonpolar HAA content.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Food Science & Technology
Xiaoyu Yin, Hongzhen Du, Ming Xu, Qian Chen, Baohua Kong
Summary: This study evaluated the HAA levels and quality characteristics of Harbin red sausages in the northern Chinese market, finding differences between traditional and conventional sausages in terms of moisture content and hardness. The total HAA content was as high as 360.73 ng/g, with Norharman and Harman showing significantly higher levels. Traditional sausages also had higher HAA contents compared to conventional sausages.
Article
Food Science & Technology
Chen-Xia Zhang, Shou-Tao Wang, Meng-Le Li, Wei-Wei Ma, Mi Zhang, Zhao Qin, Xue-De Wang, Hua-Min Liu, Yu-Xiang Ma
Summary: The aim of this study was to evaluate the effect of Chinese quince proanthocyanidins (PAs) on the deterioration and heterocyclic aromatic amine (HAA) formation in soybean oil during deep-fat frying. The results showed that adding PAs can reduce the accumulation of oil degradation products, enhance frying performance, and decrease the formation of HAAs. PA-100 and PA-140 performed better than Tea-PP in these aspects. Adding PA-100 and PA-140 not only decreased oxidation indices and tocopherols loss, but also inhibited HAA formation by 14.82%-30.64% and 19.52%-54.24% respectively. Multivariate analysis revealed that PA-140 had a stronger effect than PA-100 in enhancing frying performance and suppressing HAA generation. This study provides evidence for using PAs from Chinese quince as stabilizers of frying oils and inhibitors of HAA formation in the food industry.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Behavioral Sciences
Matthias Staudigel, Beate Brandl, Jutta Roosen, Eva Kiesswetter, Hanna M. Siebentritt, Nina Wawro, Jakob Linseisen, Thomas Skurk, Dorothee Volkert, Hans Hauner
Summary: The study examines the association between eating motives and anthropometry, body composition, and dietary intake. Results show that the Health motive is positively associated with fat-free mass and negatively associated with waist circumference in men, while the Need & Hunger motive is positively associated with fat-free mass and negatively associated with waist circumference in women. Other motives are related to dietary intake but not anthropometry or body composition.
Article
Medicine, General & Internal
Timo Schmitz, Bastian Wein, Heiko Methe, Jakob Linseisen, Margit Heier, Annette Peters, Christa Meisinger
Summary: The aim of this study was to examine the predictive value of specific changes in admission ECG on long-term outcome in acute myocardial infarction (AMI). The study found that ST-segment depressions and BBB admission ECGs are associated with higher long-term mortality in AMI patients, while a normal ECG is associated with lower long-term mortality.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Oncology
Fabio Girardi, Veronica Di Carlo, Charles Stiller, Gemma Gatta, Ryan R. Woods, Otto Visser, Brigitte Lacour, Thomas C. Tucker, Michel P. Coleman, Claudia Allemani
Summary: This study provides comprehensive data on global trends in population-based survival for childhood brain tumors. The researchers used a revised version of the International Classification of Childhood Cancer and estimated survival rates for different histology groups. The findings have important implications for public health.
Article
Clinical Neurology
Katharina Seystahl, Juliane Schweizer, Mira Katan, Sung Ju Weber, Alessia Hug, Miriam Wanner, Andreas R. Luft, Sabine Rohrmann, Susanne Wegener, Michael Weller
Summary: Cancer is not a risk factor for stroke-associated infections in stroke patients. The incidence, characteristics, and treatment of infections did not differ significantly between stroke patients with and without cancer. However, both cancer and stroke-associated infections were associated with in-hospital mortality.
NEURO-ONCOLOGY PRACTICE
(2023)
Article
Nutrition & Dietetics
Nena Karavasiloglou, Giulia Pestoni, Sarah Theresa Pannen, Katja Angela Schoenenberger, Tilman Kuhn, Sabine Rohrmann
Summary: This study investigated the adherence to cancer prevention recommendations in Switzerland and found that a high proportion of the population did not closely follow the recommendations. Women and individuals with higher education were more likely to adhere to the recommendations, while current smokers were less likely to do so. Education and policy actions are needed to promote cancer-protective lifestyles.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Nutrition & Dietetics
Flurina Suter, Giulia Pestoni, Janice Sych, Sabine Rohrmann, Julia Braun
Summary: The study identified significant associations between alcohol consumption and mortality from all-cancer and upper aero-digestive tract cancer, highlighting the need for further research to improve alcohol prevention strategies and reduce avoidable deaths in Switzerland.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Virology
Inge Kirchberger, Daniela Peilstoecker, Tobias D. Warm, Jakob Linseisen, Alexander Hyhlik-Duerr, Christine Meisinger, Yvonne Gosslau
Summary: Studies have shown that a significant proportion of non-hospitalized COVID-19 patients experience cognitive problems, including difficulties with memory and concentration. Factors such as level of education, age, and depression have been found to be associated with these cognitive impairments. Early identification of mild cognitive impairment is crucial in providing effective interventions for these patients.
Article
Oncology
Maria-Eleni Syleouni, Nena Karavasiloglou, Laura Manduchi, Miriam Wanner, Dimitri Korol, Laura Ortelli, Andrea Bordoni, Sabine Rohrmann
Summary: We developed an automated approach to predict the occurrence of any second breast cancer using patient-level data and validated the models with an external dataset. The best-performing model identified key characteristics contributing to a high second breast cancer risk, and a feed-forward neural network showed the best generalizability across different machine learning algorithms.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Virology
Inge Kirchberger, Christine Meisinger, Tobias D. Warm, Alexander Hyhlik-Duerr, Jakob Linseisen, Yvonne Gosslau
Summary: This study investigated the symptoms, healthcare needs, utilization, and satisfaction of healthcare services in a German sample of non-hospitalized individuals with post-COVID-19 syndrome (PCS) two years after SARS-CoV-2 infection. The results showed that a majority of participants experienced various symptoms, increased healthcare utilization, lack of understanding about persistent symptoms, and difficulties in finding competent healthcare providers.
Article
Clinical Neurology
Christa Meisinger, Dennis Freuer, Timo Schmitz, Michael Ertl, Philipp Zickler, Markus Naumann, Jakob Linseisen
Summary: This cross-sectional study aimed to evaluate potential associations between the etiologic subtypes of ischemic stroke and blood-based proteins. The study found that stromal-cell-derived-factor 1 alpha (SDF-1a) showed significantly higher serum levels in cardioembolic stroke compared with large vessel atherosclerotic stroke, while interleukin-6 (IL-6) and macrophage migration inhibitory factor (MIF) levels were significantly lower in the small vessel stroke subtype compared to the large vessel stroke subtype.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Nutrition & Dietetics
Sarah T. Pannen, Roland Gassmann, Robert Vorburger, Sabine Rohrmann, Janice Sych, Nina Steinemann
Summary: This article introduces a semiquantitative, multilingual electronic FFQ for real-time dietary intake assessment in the Swiss adult population, which has been validated in a nationally representative survey. Through stepwise regression analysis, 118 foods contributing to >90% of the variance in energy and six nutrients intake were selected and standardized to define an 83-item food list, covering >90% of the intake of key nutrients in the entire study population.
Article
Nutrition & Dietetics
Britta Renner, Anette E. Buyken, Kurt Gedrich, Stefan Lorkowski, Bernhard Watzl, Jakob Linseisen, Hannelore Daniel
Summary: Research on personalized nutrition has shown limited effectiveness and there are concerns about its impact on health inequality. To address these issues, a new approach called adaptive personalized nutrition advice systems (APNASs) is proposed. This approach aims to tailor personalized advice to individual needs, capacities, and receptivity in real-life food environments, encompassing broadened goals and personalized behavior change processes. Digital nutrition ecosystems enable continuous monitoring and support in food environments.
ADVANCES IN NUTRITION
(2023)
Article
Oncology
Miriam Wanner, Maria-Eleni Syleouni, Nena Karavasiloglou, Manuela Limam, Esther Bastiaannet, Dimitri Korol, Sabine Rohrmann
Summary: This study aimed to evaluate the trends in 5-year relative survival of patients with breast, prostate, lung, colorectal cancer, and skin melanoma in Zurich, Switzerland. The results showed a significant increase in relative survival rate between 1980 and 1989, and 2010 and 2015, likely due to improved awareness, diagnostic methods, and treatments for cancer. The high relative survival rate for stage I tumors reflects the efforts made in early detection.
Article
Medicine, General & Internal
Maximilian Iglesias Morcillo, Dennis Freuer, Annette Peters, Margit Heier, Christine Meisinger, Jakob Linseisen
Summary: This study investigated the relationship between BMI and waist circumference with plasma concentrations of coagulation factors in the general population. The results showed significant associations between BMI and waist circumference with various coagulation factors, suggesting that the modification of the coagulation profile could be a potential target for primary prevention in obese individuals.
MEDICINA-LITHUANIA
(2023)
Article
Oncology
Xing Jiang, Giulia Pestoni, Linda Vinci, Flurina Suter, Matthias Lorez, Sabine Rohrmann, Nena Karavasiloglou
Summary: This study aimed to estimate the proportion and number of incident cancer cases in Switzerland between 2015 and 2019 that were attributable to modifiable lifestyle risk factors. The results showed that 25.2% of potentially preventable cancer cases in Switzerland during this period were linked to these risk factors. The proportion and numbers were slightly larger in males than in females, and variations were observed between language regions. Tobacco smoking, excess body weight, and high alcohol consumption were the leading contributors to lifestyle-attributable cancer cases. The observed differences in leading risk factors within Switzerland and compared to other countries emphasize the need for regionally and nationally tailored cancer prevention and education strategies.
INTERNATIONAL JOURNAL OF CANCER
(2023)
