Role of Vascular Inflammation in Coronary Artery Disease: Potential of Anti-inflammatory Drugs in the Prevention of Atherothrombosis

Effect of Darapladib on Major Coronary Events After an Acute Coronary Syndrome

(2014) Michelle L. O’Donoghue et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Varespladib and Cardiovascular Events in Patients With an Acute Coronary Syndrome

(2014) Stephen J. Nicholls et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Darapladib for Preventing Ischemic Events in Stable Coronary Heart Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

New Drug Avenues for Cardioprotection in Patients with Acute Myocardial Infarction

(2013) François Roubille et al.   American Journal of Cardiovascular Drugs

Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarction with ST-Segment Elevation

(2013) Daniel Medeiros Moreira et al.   CARDIOLOGY

Anti-Atherogenic Effects of Methotrexate Carried by a Lipid Nanoemulsion That Binds to LDL Receptors in Cholesterol-fed Rabbits

(2013) Adriana Bulgarelli et al.   CARDIOVASCULAR DRUGS AND THERAPY

Cytotoxic and Proinflammatory CD8 + T Lymphocytes Promote Development of Vulnerable Atherosclerotic Plaques in ApoE-Deficient Mice

(2013) Tin Kyaw et al.   CIRCULATION

2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

(2013) et al.   CIRCULATION

Heart Disease and Stroke Statistics—2014 Update

(2013) Alan S. Go et al.   CIRCULATION

Pro-Inflammatory Genetic Markers of Atherosclerosis

(2013) Egle Incalcaterra et al.   Current Atherosclerosis Reports

Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis

(2013) S. Kaptoge et al.   EUROPEAN HEART JOURNAL

Inflammation and coagulation in atherosclerosis

(2013) K. A. Krychtiuk et al.   Hamostaseologie

Adaptive immunity in atherogenesis: new insights and therapeutic approaches

(2013) Andrew H. Lichtman et al.   JOURNAL OF CLINICAL INVESTIGATION

BAFF Receptor Deficiency Reduces the Development of Atherosclerosis in Mice—Brief Report

(2012) Andrew P. Sage et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease

(2012) Stephan D. Fihn et al.   CIRCULATION

Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen

(2012) Paul M Ridker et al.   CIRCULATION

2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction

(2012) et al.   CIRCULATION

Low-Dose Colchicine for Secondary Prevention of Cardiovascular Disease

(2012) Stefan M. Nidorf et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

(2012)   LANCET

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

(2012)   LANCET

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

(2012) Tin Kyaw et al.   PLoS One

A Variant In the Abo Gene Explains the Variation in Soluble E-Selectin Levels—Results from Dense Genotyping in Two Independent Populations

(2012) Mahir Karakas et al.   PLoS One

Immediate and past cumulative effects of oral glucocorticoids on the risk of acute myocardial infarction in rheumatoid arthritis: a population-based study

(2012) J. A. Avina-Zubieta et al.   RHEUMATOLOGY

A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation

(2012) Silvia Naitza et al.   PLoS Genetics

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

(2011) Paul M Ridker et al.   AMERICAN HEART JOURNAL

Effect of CC Chemokine Receptor 2 CCR2 Blockade on Serum C-Reactive Protein in Individuals at Atherosclerotic Risk and With a Single Nucleotide Polymorphism of the Monocyte Chemoattractant Protein-1 Promoter Region

(2011) Jim Gilbert et al.   AMERICAN JOURNAL OF CARDIOLOGY

Endothelial C-reactive protein increases platelet adhesion under flow conditions

(2011) Etty Grad et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Heat Shock Protein 60 and Immune Inflammatory Responses in Atherosclerosis

(2011) Cecilia Grundtman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

B1a B Lymphocytes Are Atheroprotective by Secreting Natural IgM That Increases IgM Deposits and Reduces Necrotic Cores in Atherosclerotic Lesions

(2011) Tin Kyaw et al.   CIRCULATION RESEARCH

Current understanding of the role of B cell subsets and intimal and adventitial B cells in atherosclerosis

(2011) Tin Kyaw et al.   CURRENT OPINION IN LIPIDOLOGY

Treatment With Methotrexate Inhibits Atherogenesis in Cholesterol-Fed Rabbits

(2011) Adriana Bulgarelli et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Treatment With 5-Lipoxygenase Inhibitor VIA-2291 (Atreleuton) in Patients With Recent Acute Coronary Syndrome

(2010) Jean-Claude Tardif et al.   Circulation-Cardiovascular Imaging

The complement component C5a is present in human coronary lesions in vivo and induces the expression of MMP-1 and MMP-9 in human macrophages in vitro

(2010) Walter S. Speidl et al.   FASEB JOURNAL

B cell depletion reduces the development of atherosclerosis in mice

(2010) Hafid Ait-Oufella et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conventional B2 B Cell Depletion Ameliorates whereas Its Adoptive Transfer Aggravates Atherosclerosis

(2010) T. Kyaw et al.   JOURNAL OF IMMUNOLOGY

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Immunoglobulin M Is Required for Protection Against Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

(2009) Myles J. Lewis et al.   CIRCULATION

Effects of rituximab treatment on endothelial dysfunction, carotid atherosclerosis, and lipid profile in rheumatoid arthritis

(2009) György Kerekes et al.   CLINICAL RHEUMATOLOGY

The Effects of METhotrexate Therapy on the Physical Capacity of Patients With ISchemic Heart Failure: A Randomized Double-Blind, Placebo-Controlled Trial (METIS Trial)

(2009) Daniel Medeiros Moreira et al.   JOURNAL OF CARDIAC FAILURE

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis

(2009)   LANCET

The effect of methotrexate on cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review

(2009) S. L. Westlake et al.   RHEUMATOLOGY

Relationship of Admission Neutrophil Count to Microvascular Injury, Left Ventricular Dilation, and Long-Term Outcome in Patients Treated With Primary Angioplasty for Acute Myocardial Infarction

(2008) Takefumi Takahashi et al.   CIRCULATION JOURNAL

Peripheral B cell subsets

(2008) David Allman et al.   CURRENT OPINION IN IMMUNOLOGY

Pexelizumab in ischemic heart disease: A systematic review and meta-analysis on 15,196 patients

(2008) L. Testa et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial

(2008) Jean-Claude Tardif et al.   LANCET

Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

(2008) Christophe Piot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Colchicine Update: 2008

(2008) Robert A. Terkeltaub   SEMINARS IN ARTHRITIS AND RHEUMATISM

Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study

(2008) Antonio Naranjo et al.   ARTHRITIS RESEARCH & THERAPY