Antiplatelet and Anticoagulant Therapy for Atherothrombotic Disease: The Role of Current and Emerging Agents
出版年份 2013 全文链接
标题
Antiplatelet and Anticoagulant Therapy for Atherothrombotic Disease: The Role of Current and Emerging Agents
作者
关键词
Percutaneous Coronary Intervention, Acute Coronary Syndrome, Clopidogrel, Dabigatran, Rivaroxaban
出版物
American Journal of Cardiovascular Drugs
Volume 13, Issue 4, Pages 233-250
出版商
Springer Nature
发表日期
2013-05-02
DOI
10.1007/s40256-013-0022-7
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms (CYP2C19, ABCB1, PON1), Noncompliance, Diet, Smoking, Co-Medications (Including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function
- (2013) Andrew L. Frelinger et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Design and rationale of the Treatment of Acute Coronary Syndromes with Otamixaban trial: A double-blind triple-dummy 2-stage randomized trial comparing otamixaban to unfractionated heparin and eptifibatide in non–ST-segment elevation acute coronary syndromes with a planned early invasive strategy
- (2012) Philippe Gabriel Steg et al. AMERICAN HEART JOURNAL
- Rationale and design of the Cangrelor versus standard therapy to acHieve optimal Management of Platelet InhibitiON PHOENIX trial
- (2012) Sergio Leonardi et al. AMERICAN HEART JOURNAL
- 2012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update)
- (2012) et al. CIRCULATION
- A Randomized, Double-Blind, Active-Controlled Phase 2 Trial to Evaluate a Novel Selective and Reversible Intravenous and Oral P2Y 12 Inhibitor Elinogrel Versus Clopidogrel in Patients Undergoing Nonurgent Percutaneous Coronary Intervention
- (2012) Robert C. Welsh et al. Circulation-Cardiovascular Interventions
- New Directions in Antiplatelet Therapy
- (2012) José Luis Ferreiro et al. Circulation-Cardiovascular Interventions
- Pharmacokinetic and Pharmacodynamic Effects of Elinogrel
- (2012) Dominick J. Angiolillo et al. Circulation-Cardiovascular Interventions
- The Evolution of Antiplatelet Therapy in the Treatment of Acute Coronary Syndromes
- (2012) Dominick J. Angiolillo DRUGS
- A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial
- (2012) Thomas J. Povsic et al. EUROPEAN HEART JOURNAL
- Bridging Antiplatelet Therapy With Cangrelor in Patients Undergoing Cardiac Surgery
- (2012) Dominick J. Angiolillo et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A Randomized, 2-Period, Crossover Design Study to Assess the Effects of Dexlansoprazole, Lansoprazole, Esomeprazole, and Omeprazole on the Steady-State Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Volunteers
- (2012) Andrew L. Frelinger et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- A Randomized Trial of Prasugrel Versus Clopidogrel in Patients With High Platelet Reactivity on Clopidogrel After Elective Percutaneous Coronary Intervention With Implantation of Drug-Eluting Stents
- (2012) Dietmar Trenk et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Safety and efficacy of protease-activated receptor-1 antagonists in patients with coronary artery disease: a meta-analysis of randomized clinical trials
- (2012) D. CAPODANNO et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Prasugrel versus Clopidogrel for Acute Coronary Syndromes without Revascularization
- (2012) Matthew T. Roe et al. NEW ENGLAND JOURNAL OF MEDICINE
- Vorapaxar in the Secondary Prevention of Atherothrombotic Events
- (2012) David A. Morrow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Bedside Monitoring to Adjust Antiplatelet Therapy for Coronary Stenting
- (2012) Jean-Philippe Collet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Risk of Intracranial Hemorrhage With Protease-Activated Receptor-1 Antagonists
- (2012) Meng Lee et al. STROKE
- A randomized, partially blinded, multicenter, active-controlled, dose-ranging study assessing the safety, efficacy, and pharmacodynamics of the REG1 anticoagulation system in patients with acute coronary syndromes: Design and rationale of the RADAR Phase IIb trial
- (2011) Thomas J. Povsic et al. AMERICAN HEART JOURNAL
- Rationale and design of the Anti-Xa Therapy to Lower cardiovascular events in Addition to standard therapy in Subjects with Acute Coronary Syndrome–Thrombolysis in Myocardial Infarction 51 (ATLAS-ACS 2 TIMI 51) trial: A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of rivaroxaban in subjects with acute coronary syndrome
- (2011) C. Michael Gibson et al. AMERICAN HEART JOURNAL
- Inhibitors of the Platelet Thrombin Receptor
- (2011) Frans Van de Werf CIRCULATION
- Randomized Trial of Atopaxar in the Treatment of Patients With Coronary Artery Disease
- (2011) Stephen D. Wiviott et al. CIRCULATION
- Safety and Tolerability of Atopaxar in the Treatment of Patients With Acute Coronary Syndromes
- (2011) Michelle L. O'Donoghue et al. CIRCULATION
- Ticagrelor Compared With Clopidogrel by Geographic Region in the Platelet Inhibition and Patient Outcomes (PLATO) Trial
- (2011) Kenneth W. Mahaffey et al. CIRCULATION
- Clinical Events as a Function of Proton Pump Inhibitor Use, Clopidogrel Use, and Cytochrome P450 2C19 Genotype in a Large Nationwide Cohort of Acute Myocardial Infarction
- (2011) Tabassome Simon et al. CIRCULATION
- Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial
- (2011) J. Oldgren et al. EUROPEAN HEART JOURNAL
- Optimizing Platelet Inhibition in Clopidogrel Poor Metabolizers
- (2011) Dominick J. Angiolillo et al. JACC-Cardiovascular Interventions
- Standard- vs High-Dose Clopidogrel Based on Platelet Function Testing After Percutaneous Coronary Intervention
- (2011) Matthew J. Price JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Safety and Exploratory Efficacy of the Novel Thrombin Receptor (PAR-1) Antagonist SCH530348 for Non-ST-Segment Elevation Acute Coronary Syndrome
- (2011) Shinya Goto et al. Journal of Atherosclerosis and Thrombosis
- 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention
- (2011) Glenn N. Levine et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Apixaban with Antiplatelet Therapy after Acute Coronary Syndrome
- (2011) John H. Alexander et al. NEW ENGLAND JOURNAL OF MEDICINE
- Rivaroxaban in Patients with a Recent Acute Coronary Syndrome
- (2011) Jessica L. Mega et al. NEW ENGLAND JOURNAL OF MEDICINE
- Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes
- (2011) Pierluigi Tricoci et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inhibición del receptor plaquetario P2Y12 de adenosina difosfato plaquetario: efectos beneficiosos y limitaciones de las estrategias terapéuticas actuales y perspectivas futuras
- (2011) Dominick J. Angiolillo et al. REVISTA ESPANOLA DE CARDIOLOGIA
- Rationale and design of the randomized, double-blind trial testing INtraveNous and Oral administration of elinogrel, a selective and reversible P2Y12-receptor inhibitor, versus clopidogrel to eVAluate Tolerability and Efficacy in nonurgent Percutaneous Coronary Interventions patients (INNOVATE-PCI)
- (2010) Sergio Leonardi et al. AMERICAN HEART JOURNAL
- Study design and rationale of a comparison of prasugrel and clopidogrel in medically managed patients with unstable angina/non–ST-segment elevation myocardial infarction: The TaRgeted platelet Inhibition to cLarify the Optimal strateGy to medicallY manage Acute Coronary Syndromes (TRILOGY ACS) trial
- (2010) Chee Tang Chin et al. AMERICAN HEART JOURNAL
- Heart Disease and Stroke Statistics—2011 Update
- (2010) Véronique L. Roger et al. CIRCULATION
- Basic Principles of Platelet Biology and Clinical Implications
- (2010) Dominick J. Angiolillo et al. CIRCULATION JOURNAL
- Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison Studies
- (2010) D J Angiolillo et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Double-blind, placebo-controlled Phase II studies of the protease-activated receptor 1 antagonist E5555 (atopaxar) in Japanese patients with acute coronary syndrome or high-risk coronary artery disease
- (2010) S. Goto et al. EUROPEAN HEART JOURNAL
- Novel Anticoagulants for Stroke Prevention in Atrial Fibrillation
- (2010) Stephan H. Schirmer et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- A 2-Step Mechanism of Arterial Thrombus Formation Induced by Human Atherosclerotic Plaques
- (2010) Armin J. Reininger et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial
- (2010) Shamir R Mehta et al. LANCET
- Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis
- (2010) Jessica L Mega et al. LANCET
- Antithrombotic drugs for patients with ischaemic stroke and transient ischaemic attack to prevent recurrent major vascular events
- (2010) Graeme J Hankey et al. LANCET NEUROLOGY
- Clopidogrel with or without Omeprazole in Coronary Artery Disease
- (2010) Deepak L. Bhatt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dose Comparisons of Clopidogrel and Aspirin in Acute Coronary Syndromes
- (2010) NEW ENGLAND JOURNAL OF MEDICINE
- Roles and interactions among protease-activated receptors and P2ry12 in hemostasis and thrombosis
- (2010) I. Cornelissen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evaluation of a novel antiplatelet agent for secondary prevention in patients with a history of atherosclerotic disease: Design and rationale for the Thrombin-Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P)-TIMI 50 trial
- (2009) David A. Morrow et al. AMERICAN HEART JOURNAL
- The Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRA•CER) trial: study design and rationale
- (2009) The TRA•CER Executive and Steering Committees AMERICAN HEART JOURNAL
- Advances in Antiplatelet Therapy: Agents in Clinical Development
- (2009) Dominick J. Angiolillo et al. AMERICAN JOURNAL OF CARDIOLOGY
- Blood Coagulation: Hemostasis and Thrombin Regulation
- (2009) Kenichi A. Tanaka et al. ANESTHESIA AND ANALGESIA
- Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases
- (2009) Jolanta M Siller-Matula et al. BRITISH JOURNAL OF PHARMACOLOGY
- Apixaban, an Oral, Direct, Selective Factor Xa Inhibitor, in Combination With Antiplatelet Therapy After Acute Coronary Syndrome
- (2009) CIRCULATION
- Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Coronary Artery Disease
- (2009) Paul A. Gurbel et al. CIRCULATION
- New antithrombotic agents: are they needed and what can they offer to patients with a non-ST-elevation acute coronary syndrome?
- (2009) F. Van de Werf EUROPEAN HEART JOURNAL
- Platelet thrombin receptor antagonism and atherothrombosis
- (2009) D. J. Angiolillo et al. EUROPEAN HEART JOURNAL
- Platelet receptors and signaling in the dynamics of thrombus formation
- (2009) J. Rivera et al. HAEMATOLOGICA
- Risk of Adverse Outcomes Associated With Concomitant Use of Clopidogrel and Proton Pump Inhibitors Following Acute Coronary Syndrome
- (2009) P. Michael Ho JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Otamixaban for the treatment of patients with non-ST-elevation acute coronary syndromes (SEPIA-ACS1 TIMI 42): a randomised, double-blind, active-controlled, phase 2 trial
- (2009) Marc S Sabatine et al. LANCET
- Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46): a randomised, double-blind, phase II trial
- (2009) JL Mega et al. LANCET
- Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study
- (2009) Richard C Becker et al. LANCET
- Intravenous Platelet Blockade with Cangrelor during PCI
- (2009) Deepak L. Bhatt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes
- (2009) Lars Wallentin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Platelet Inhibition with Cangrelor in Patients Undergoing PCI
- (2009) Robert A. Harrington et al. NEW ENGLAND JOURNAL OF MEDICINE
- The clinical implications of new oral anticoagulants: Will the potential advantages be achieved?
- (2009) K. W. Phillips et al. THROMBOSIS AND HAEMOSTASIS
- Cell Adhesion Mechanisms in Platelets
- (2008) David Varga-Szabo et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity
- (2008) Samuel Chackalamannil et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cytochrome P-450 Polymorphisms and Response to Clopidogrel
- (2008) Jessica L. Mega et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetic Determinants of Response to Clopidogrel and Cardiovascular Events
- (2008) Tabassome Simon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Platelet ADP-receptor antagonists for cardiovascular disease: past, present and future
- (2008) Nina C Raju et al. Nature clinical practice. Cardiovascular medicine
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