Article
Hematology
Chor-Cheung Frankie Tam, Yap-Hang Chan, Yuen-Kwun Wong, Zhen Li, Xiurui Zhu, Kuo-Jung Su, Anindita Ganguly, Kuoyuan Hwa, Xuefeng B. Ling, Hung-Fat Tse
Summary: This study compared the effects of ticagrelor and aspirin monotherapy on vascular endothelial function in patients with prior acute coronary syndrome. The results showed that ticagrelor significantly improved brachial flow-mediated dilation compared with aspirin, but had no significant effect on platelet activation markers and endothelial progenitor cell count. The analysis of multi-omics pathways also found associations between ticagrelor treatment and changes in metabolism and lipid levels.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2022)
Letter
Medicine, General & Internal
John A. Bittl
Summary: The article discusses the preference for antithrombotic therapy in patients with acute coronary syndromes and the difference between preference and actual practice. It also mentions a new study, but does not explicitly state whether this new study can explain the discrepancy.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Medicine, General & Internal
Brian A. Bergmark, Njambi Mathenge, Piera A. Merlini, Marilyn B. Lawrence-Wright, Robert P. Giugliano
Summary: Although progress has been made in diagnosing and treating acute coronary syndromes, cardiovascular disease remains a leading cause of death globally. High-sensitivity troponin assays have allowed for rapid diagnosis in suspected cases. Dual antiplatelet therapy and additional preventive measures are recommended. The diagnosis and management of acute coronary syndromes continue to evolve, especially in response to the COVID-19 pandemic.
Article
Cardiac & Cardiovascular Systems
Shqipdona Lahu, Gjin Ndrepepa, Franz-Josef Neumann, Maurizio Menichelli, Isabell Bernlochner, Gert Richardt, Jochen Wohrle, Bernhard Witzenbichler, Rayyan Hemetsberger, Katharina Mayer, Ibrahim Akin, Salvatore Cassese, Senta Gewalt, Erion Xhepa, Sebastian Kufner, Christian Valina, Hendrik B. Sager, Michael Joner, Tareq Ibrahim, Karl-Ludwig Laugwitz, Heribert Schunkert, Stefanie Schupke, Adnan Kastrati
Summary: Pre-admission treatment with aspirin and/or clopidogrel does not affect the efficacy and safety of ticagrelor and prasugrel in patients with acute coronary syndromes.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2022)
Article
Medicine, General & Internal
Song-Tao Gao, Yu Wang, Lei Ma
Summary: This study aimed to investigate the effects of ticagrelor and clopidogrel dual antiplatelet therapy on platelet function, clot formation, and cardiac function in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI). The results showed that ticagrelor was more effective in platelet inhibition and improvement of cardiac function compared to clopidogrel, suggesting its clinical recommendation for ACS patients undergoing PCI.
Article
Cardiac & Cardiovascular Systems
Wenxing Peng, Yunnan Zhang, Yang Lin
Summary: This study mainly explored the effects of low-dose ticagrelor in Chinese ACS patients. The results showed that the platelet aggregation rates induced by ADP were comparable in the ticagrelor 60 mg and ticagrelor 90 mg groups, and both of these groups had significantly more potent antiplatelet activity compared to clopidogrel.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, Research & Experimental
Dandan Li, Yang Sun, Xiaoran Ye, Lanting Li, Yundai Chen, Daowen Wang
Summary: In Chinese ACS patients undergoing PCI with second-generation DESs, outpatient use of clopidogrel dual antiplatelet therapy was associated with a reduction in NACCE and bleeding compared to ticagrelor therapy.
ADVANCES IN THERAPY
(2022)
Review
Medicine, General & Internal
Clara Bonanad, Francisca Esteve-Claramunt, Sergio Garcia-Blas, Ana Ayesta, Pablo Diez-Villanueva, Jose-Angel Perez-Rivera, Jose Luis Ferreiro, Joaquim Canoves, Francisco Lopez-Fornas, Albert Ariza Sole, Sergio Raposerias, David Vivas, Regina Blanco, Daznia Bompart Berroteran, Alberto Cordero, Julio Nunez, Lorenzo Facila, Ivan J. Nunez-Gil, Jose Luis Gorriz, Vicente Bodi, Manuel Martinez-Selles, Juan Miguel Ruiz Nodar, Francisco Javier Chorro
Summary: The treatment of acute coronary syndrome (ACS) in elderly patients is challenging due to their characteristics and lack of specific recommendations. This review summarizes the current evidence on oral antithrombotic therapy in elderly patients, discussing peculiarities of dual antiplatelet therapy (DAPT) in ACS management and analyzing antithrombotic strategies in patients with atrial fibrillation (AF) and coronary artery disease (CAD).
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Alexandru Burlacu, Mariana Floria, Crischentian Brinza, Adrian Covic
Summary: This meta-analysis aimed to compare the efficacy and safety endpoints of ticagrelor and clopidogrel in end-stage kidney disease (ESKD) patients on chronic dialysis presenting with acute or chronic coronary syndromes (ACS or CCS). The results showed no significant difference in efficacy or safety outcomes between ticagrelor and clopidogrel. Further randomized controlled trials are needed to establish the optimal antiplatelet therapy in this population.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
J. J. Coughlan, Alp Aytekin, Shqipdona Lahu, Gjin Ndrepepa, Maurizio Menichelli, Katharina Mayer, Jochen Wohrle, Isabell Bernlochner, Senta Gewalt, Bernhard Witzenbichler, Willibald Hochholzer, Dirk Sibbing, Salvatore Cassese, Dominick J. Angiolillo, Rayyan Hemetsberger, Christian Valina, Arne Mueller, Sebastian Kufner, Christoph Liebetrau, Erion Xhepa, Alexander Hapfelmeier, Hendrik B. Sager, Michael Joner, Massimiliano Fusaro, Gert Richardt, Karl Ludwig Laugwitz, Franz Josef Neumann, Heribert Schunkert, Stefanie Schuepke, Adnan Kastrati
Summary: This study compared the safety and efficacy of ticagrelor and prasugrel hydrochloride for patients with ACS treated with PCI. Results showed that the incidence of the primary composite end point was lower in the prasugrel group compared to the ticagrelor group, while bleeding events were similar between the two groups.
Article
Cardiac & Cardiovascular Systems
Mark R. Thomas, Stefan K. James, Richard C. Becker, Anders Himmelmann, Hugo A. Katus, Christopher P. Cannon, Philippe Gabriel Steg, Agneta Siegbahn, Tatevik Lakic, Robert F. Storey, Lars Wallentin
Summary: Elevated baseline inflammatory markers are associated with increased risk of adverse cardiovascular events in patients with acute coronary syndrome. Ticagrelor consistently shows relative cardiovascular benefit compared to clopidogrel in each quartile of inflammatory markers. High levels of inflammatory markers indicate higher cardiovascular risk and greater absolute risk reduction with ticagrelor.
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
(2021)
Article
Medicine, General & Internal
Felice Gragnano, Elisabetta Moscarella, Paolo Calabro, Arturo Cesaro, Pia Clara Pafundi, Alfonso Ielasi, Giuseppe Patti, Ilaria Cavallari, Emilia Antonucci, Plinio Cirillo, Pasquale Pignatelli, Gualtiero Palareti, Francesco Pelliccia, Carlo Gaudio, Ferdinando Carlo Sasso, Vittorio Pengo, Paolo Gresele, Rossella Marcucci
Summary: In patients with acute coronary syndrome and high bleeding risk, there was no significant difference in ischemic and bleeding events at 1 year between those treated with clopidogrel and ticagrelor. The duration of dual antiplatelet therapy, rather than the specific type of therapy, was associated with long-term outcomes.
INTERNAL AND EMERGENCY MEDICINE
(2021)
Article
Pharmacology & Pharmacy
Alexandru-George Cotoban, Cristian Alexandru Udroiu, Dragos Vinereanu
Summary: In Romania, invasively managed NSTE-ACS patients commonly receive DAPT, P2Y12 inhibitor pretreatment, and single vessel PCI, while the introduction of full reimbursement for ticagrelor since November 2017 has doubled its usage rate.
AMERICAN JOURNAL OF THERAPEUTICS
(2021)
Article
Medicine, General & Internal
Erik Bjorklund, Carl Johan Malm, Susanne J. Nielsen, Emma C. Hansson, Hans Tygesen, Birgitta S. Romlin, Andreas Martinsson, Elmir Omerovic, Aldina Pivodic, Anders Jeppsson
Summary: This study compared clinical outcomes of patients with acute coronary syndrome treated with aspirin and ticagrelor vs aspirin alone after artery bypass grafting. The results showed that dual antiplatelet therapy did not significantly reduce major adverse cardiovascular events compared with aspirin monotherapy, but was associated with an increased risk of major bleeding. Further research is needed to determine optimal antiplatelet therapy in this group.
Article
Cardiac & Cardiovascular Systems
Guiomar Mendieta, Shamir Mehta, Usman Baber, Dominick J. Angiolillo, Carlo Briguori, David Cohen, Timothy Collier, George Dangas, Dariusz Dudek, Javier Escaned, Robert Gil, Birgit Vogel, Davide Cao, Alessandro Spirito, Kurt Huber, Adnan Kastrati, Upendra Kaul, Ran Kornowski, Mitchell W. Krucoff, Vijay Kunadian, David J. Moliterno, E. Magnus Ohman, Gennaro Sardella, Samantha Sartori, Samin Sharma, Richard Shlofmitz, P. Gabriel Steg, Ya-Ling Han, Stuart Pocock, C. Michael Gibson, Roxana Mehran
Summary: In high-risk patients, ticagrelor monotherapy reduces bleeding events without increasing the risk of ischemic events compared to dual antiplatelet therapy. The benefit of ticagrelor monotherapy is consistent across different bleeding and ischemic risk levels.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Nathaniel R. Smilowitz, Gabriel Redel-Traub, Jeffery S. Berger
Summary: The study found that microvascular disease (MVD) had a prevalence of 5.0% in noncardiac surgeries, and was associated with age, sex, and coronary artery disease (CAD). Patients with MVD were older and more likely to have traditional cardiovascular risk factors. MVD was associated with postoperative mortality and major adverse cardiac events (MACE).
AMERICAN JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Kara R. Melmed, Meng Cao, Siddhant Dogra, Ruina Zhang, Shadi Yaghi, Ariane Lewis, Rajan Jain, Seda Bilaloglu, Ji Chen, Barry M. Czeisler, Eytan Raz, Aaron Lord, Jeffrey S. Berger, Jennifer A. Frontera
Summary: This study assessed risk factors associated with intracerebral hemorrhage in COVID-19 patients, finding that anticoagulation use was linked to an increased risk of intracerebral hemorrhage and was associated with higher mortality. Further investigation is needed to understand the underlying mechanisms and develop prevention strategies in this population.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2021)
Article
Cardiac & Cardiovascular Systems
Nathaniel R. Smilowitz, Varun Subashchandran, Eugene Yuriditsky, James M. Horowitz, Harmony R. Reynolds, Judith S. Hochman, Jeffrey S. Berger
Summary: The study compared the incidence of thrombosis in patients hospitalized with non-COVID-19 acute viral respiratory illnesses from 2012 to 2014 to those hospitalized with COVID-19 in a large health system in New York. It was found that the risk of thrombosis was lower in patients with viral respiratory illnesses compared to those with COVID-19. Further investigations into thrombosis mechanisms and risk reduction strategies in viral respiratory infections are needed.
AMERICAN HEART JOURNAL
(2021)
Article
Respiratory System
Jemi Galani, Hillary Mulder, Frank W. Rockhold, E. Hope Weissler, Iris Baumgartner, Jeffrey S. Berger, Juuso Blomster, F. Gerry R. Fowkes, William R. Hiatt, Brian G. Katona, Lars Norgren, Kenneth W. Mahaffey, Jennifer K. Quint, Manesh R. Patel, W. Schuyler Jones
Summary: Patients with comorbid PAD and COPD have a higher risk of major adverse cardiovascular events, particularly myocardial infarction, compared to those without COPD. They are also more likely to be hospitalized for respiratory-related issues and to discontinue the study drug prematurely.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2021)
Article
Cardiac & Cardiovascular Systems
Harvey D. White, Sean M. O'Brien, Karen P. Alexander, William E. Boden, Sripal Bangalore, Jianghao Li, Cholenahally N. Manjunath, Jose Luis Lopez-Sendon, Jesus Peteiro, Gilbert Gosselin, Jeffrey S. Berger, Aldo Pietro Maggioni, Harmony R. Reynolds, Judith S. Hochman, David J. Maron
Summary: This prespecified analysis of the ISCHEMIA randomized clinical trial found that patients in the conservative management group had higher days alive out of hospital (DAOH) in the first 2 years, but no significant difference at 4 years. Early decrease in DAOH in the invasive management group was attributed to protocol-assigned procedures. Hospital stays for myocardial infarction and unstable angina during follow-up were lower in the invasive management group. DAOH provides a patient-focused metric that can be used by clinicians and patients in shared decision-making for management of stable coronary artery disease.
Article
Medicine, Research & Experimental
Jeffrey S. Berger, Francois Laliberte, Akshay Kharat, Dominique Lejeune, Kenneth Todd Moore, Young Jung, Patrick Lefebvre, Veronica Ashton
Summary: Rivaroxaban may be a safe and effective alternative to warfarin for obese NVAF patients, with a lower risk of stroke or systemic embolism compared to warfarin. There was no significant difference in major bleeding risk between rivaroxaban and warfarin-treated patients. Subgroup analyses yielded consistent results with the overall polypharmacy analysis.
ADVANCES IN THERAPY
(2021)
Article
Peripheral Vascular Disease
Lars Norgren, Rebecca North, Iris Baumgartner, Jeffrey S. Berger, Juuso Blomster, William R. Hiatt, W. Schuyler Jones, Brian G. Katona, Kenneth W. Mahaffey, Hillary Mulder, Manesh R. Patel, Frank W. Rockhold, F. Gerry R. Fowkes
Summary: Regional variations in epidemiology, comorbidities, and outcomes of patients with PAD were found in a large international study. These differences were not explained by variation in patient inclusion criteria, concomitant diseases, risk factors, and prevention measures.
Letter
Peripheral Vascular Disease
Gabriel Redel-Traub, Nathaniel R. Smilowitz, Yuhe Xia, Jeffrey S. Berger
Article
Cardiac & Cardiovascular Systems
Jaime Ramos-Cejudo, Andrew D. Johnson, Alexa Beiser, Sudha Seshadri, Joel Salinas, Jeffrey S. Berger, Nathanael R. Fillmore, Nhan Do, Chunlei Zheng, Zanetta Kovbasyuk, Babak A. Ardekani, Pomara Nunzio, Omonigho M. Bubu, Ankit Parekh, Antonio Convit, Rebecca A. Betensky, Thomas M. Wisniewski, Ricardo S. Osorio
Summary: Platelet function in middle age is independently associated with future risk of Alzheimer's disease (AD). Individuals with a higher platelet response have a higher risk of dementia during a 20-year follow-up, highlighting the importance of platelet function in AD risk.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Michael Szarek, Connie Hess, Manesh R. Patel, W. Schuyler Jones, Jeffrey S. Berger, Iris Baumgartner, Brian Katona, Kenneth W. Mahaffey, Lars Norgren, Juuso Blomster, Frank W. Rockhold, Judith Hsia, F. Gerry R. Fowkes, Marc P. Bonaca
Summary: This study analyzed total cardiovascular and limb events in patients with symptomatic PAD, finding that the number of total events is nearly twice that of first events and is related to the number of affected vascular territories. These findings highlight the clinical importance of quantifying disease burden in terms of total events and the need for long-term preventive treatments in high-risk patient populations.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Hematology
Lucas B. Cofer, Tessa J. Barrett, Jeffrey S. Berger
Summary: Although aspirin is widely used for primary prevention of cardiovascular disease (CVD), its benefits do not outweigh its risks in large populations. The current approach of clinical trials for aspirin therapy does not consider platelet inhibition, which is a relevant mechanism of action for aspirin. Therefore, a new platelet-guided approach is proposed to identify individuals who would benefit the most from primary CVD prevention with aspirin.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Scott D. J. Solomon, Charles J. S. Lowenstein, Ankeet S. Bhatt, Alexander Peikert, Orly N. Vardeny, Mikhail N. S. Kosiborod, Jeffrey S. R. Berger, Harmony R. Reynolds, Stephanie Mavromichalis, Anya D. Barytol, Andrew D. F. Althouse, James F. S. Luther, Eric S. L. Leifer, Andrei L. Kindzelski, Mary N. Cushman, Michelle N. Z. Gong, Lucy Z. Kornblith, Pooja S. Khatri, Keri S. Kim, Lisa Baumann Kreuziger, Lana Wahid, Bridget-Anne W. Kirwan, Mark W. D. Geraci, Matthew D. S. Neal, Judith S. Hochman
Summary: This study aimed to evaluate the efficacy of using the P-selectin inhibitor crizanlizumab in reducing mortality and disease progression in COVID-19 patients. However, the results showed that the drug did not improve organ support-free days in patients hospitalized with COVID-19.
Article
Cardiac & Cardiovascular Systems
Daniel Y. Choi, Dena Hayes, Samuel D. Maidman, Nehal Dhaduk, Jill E. Jacobs, Anna Shmukler, Jeffrey S. Berger, Germaine Cuff, David Rehe, Mitchell Lee, Robert Donnino, Nathaniel R. Smilowitz
Summary: Preoperative cardiovascular risk stratification before noncardiac surgery is a common clinical challenge. Coronary calcium obtained from nongated chest CT imaging can improve preoperative clinical risk stratification before noncardiac surgery.
Review
Peripheral Vascular Disease
Muhammad Haisum Maqsood, Franz H. Messerli, Adam H. Skolnick, Jonathan D. Newman, Jeffrey S. Berger, Sripal Bangalore
Summary: This study compared the efficacy of morning versus evening dosing of antihypertensive drugs and found that evening dosing significantly reduced ambulatory blood pressure parameters and cardiovascular events, but this effect was mainly driven by trials by the Hermida group. Therefore, the timing of antihypertensive drug administration should be chosen based on convenience and minimizing undesirable effects.
Article
Cardiac & Cardiovascular Systems
Nipun Bhandari, Jonathan D. Newman, Jeffrey S. Berger, Nathaniel R. Smilowitz
Summary: This study examines the impact of diabetes mellitus on outcomes of lower extremity revascularization for peripheral artery disease and finds that diabetes is an independent risk factor for major limb amputation and 6-month hospital readmission.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai
Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg
Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce
Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson
Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin
Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir
Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis
Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai
Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ya He, Jianzhong Zhou
Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)