Article
Cardiac & Cardiovascular Systems
Chelsea Meloche, Milan Seth, Ryan D. Madder, Jacob E. Kurlander, Jessica Yaser, Joseph Chattahi, John Collins, Natesh Lingam, Dilip Arora, Hitinder S. Gurm, Devraj Sukul
Summary: This study evaluated the association between a history of gastrointestinal bleeding (GIB) and outcomes after percutaneous coronary intervention (PCI). Patients with a history of GIB were found to have increased risks of post-procedural transfusions, bleeding, and major bleeding, but no significant association with 90-day readmission or long-term survival. Adjusting for baseline characteristics, patients with a history of GIB had higher risk of in-hospital bleeding complications after PCI.
AMERICAN JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Ryan D. Madder, Milan Seth, Devraj Sukul, M. Chadi Alraies, Mansoor Qureshi, Michael Tucciarone, Frank Saltiel, Imran Qureshi, Hitinder S. Gurm
Summary: This study revealed substantial variations in intracoronary imaging (ICI) at the hospital and physician levels during percutaneous coronary intervention (PCI). The performing hospital and physician had a stronger association with ICI optimization than any patient or procedural factors, except for left main PCI.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Devraj Sukul, Milan Seth, Michael P. Thompson, Steven J. Keteyian, Thomas F. Boyden, John D. Syrjamaki, Jessica Yaser, Donald S. Likosky, Hitinder S. Gurm
Summary: Despite established benefits of cardiac rehabilitation (CR), CR use remains low. A study in Michigan found that there were significant variations in CR referral and participation rates across different hospitals and operators performing PCI procedures. Improving understanding of these variations may help develop strategies to increase overall CR participation.
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2021)
Article
Cardiac & Cardiovascular Systems
Stephanie M. Spehar, Milan Seth, Peter Henke, Khaldoon Alaswad, Theodore Schreiber, Aaron Berman, John Syrjamaki, Omar E. Ali, Yousef Bader, David Nerenz, Hitinder Gurm, Devraj Sukul
Summary: The study found that Black patients had a higher risk of 90-day readmission and cumulative mortality following PCI compared with White patients. Associations were mediated by dual eligibility, community economic well-being, and traditional cardiovascular risk factors.
AMERICAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
J. Hunter Mehaffey, J. W. Awori Hayanga, Mohammad Kawsara, Ankit Sakhuja, Christopher Mascio, J. Scott Rankin, Vinay Badhwar
Summary: Contemporary real-world data from Medicare patients with multivessel disease reveal that coronary artery bypass grafting (CABG) outcomes were superior to percutaneous coronary intervention (PCI), providing important longitudinal data to guide patient care and policy development.
ANNALS OF THORACIC SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Lorenzo Azzalini, Dimitri Karmpaliotis, Ricardo Santiago, Kambis Mashayekhi, Carlo Di Mario, Stephane Rinfret, William J. Nicholson, Mauro Carlino, Masahisa Yamane, Etsuo Tsuchikane, Emmanouil S. Brilakis
Summary: Remarkable progress has been made in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in recent years, including improvements in technical aspects, imaging, and complication management. Global collaboration has resulted in consensus on terms, indications, and clinical trial design principles, as well as the development of global consensus documents. Advances in pre-procedural and intraprocedural imaging, along with novel techniques and structured CTO crossing and complication management algorithms, have enabled a systematic and stepwise approach to this challenging intervention.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Medicine, General & Internal
David S. Eccleston, Enayet Chowdhury, Tony Rafter, Peter Sage, Alan Whelan, Christopher Reid, Danny Liew, MyNgan Duong, Nisha Schwarz, Stephen G. Worthley
Summary: This study aimed to compare long-term outcomes of new generation drug-eluting stents (DES) with other stents in Australia, and reported the clinical practice and outcomes of PCI with the Xience DES, finding that the use of Xience DES in Australia is consistent with international series.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Lorenzo Azzalini, Milan Seth, Devraj Sukul, Javier A. Valle, Edouard Daher, Brett Wanamaker, Michael T. Tucciarone, Anwar Zaitoun, Ryan D. Madder, Hitinder S. Gurm
Summary: The COVID-19 pandemic has affected the temporal trends and outcomes of patients undergoing percutaneous coronary intervention (PCI) in Michigan, leading to a reduction in PCI volume and an increase in risk-adjusted mortality. COVID-19 positive patients experienced worse outcomes.
Article
Medicine, General & Internal
Roxana Mehran, Ruth Owen, Mauro Chiarito, usman Bober, Samantha Sartori, Davide Cao, Johny Nicolas, Carlo Andrea Pivato, Matteo Nordin, Prakash Krishnan, Annapoorna Kini, Samin Shanna, Stuart Pocock, George Dangas
Summary: A simple risk score based on a large contemporary PCI cohort was developed to estimate the risk of contrast-associated acute kidney injury, which was found to be strongly associated with subsequent death.
Review
Medicine, General & Internal
Emil Julian Dabrowski, Michal Swieczkowski, Joanna Maria Dudzik, Oliwia Grunwald, Tomasz Januszko, Pawel Muszynski, Piotr Pogorzelski, Justyna Tokarewicz, Maciej Poludniewski, Marcin Kozuch, Slawomir Dobrzycki
Summary: In the aging society, coronary chronic total occlusion (CTO) has become a challenge for invasive cardiologists. Despite the lack of clear indications in guidelines, the rates of percutaneous coronary interventions (PCI) for CTO have increased. Well-conducted studies have made progress in CTO blind spots, but the results on revascularization rationale and long-term benefit of CTO are inconclusive. Our work aims to provide a comprehensive review of the latest evidence on percutaneous recanalization of coronary artery CTO, considering the uncertainties.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Anoop N. Koshy, Gennaro Giustino, Samantha Sartori, Htoo Kyaw, Mayank Yadav, Zhongjie Zhang, Amit Hooda, Ali Farooq, Parasuram Krishnamoorthy, Joseph M. Sweeny, Sahil Khera, Gregory W. Serrao, Raman Sharma, Javed Suleman, George Dangas, Annapoorna S. Kini, Roxana Mehran, Samin K. Sharma
Summary: This study compared the efficacy and safety of ticagrelor and prasugrel in a real-world patient population undergoing percutaneous coronary intervention (PCI). The results showed no difference in the risk of death or myocardial infarction (MI) between ticagrelor and prasugrel groups, but the ticagrelor cohort had significantly lower rates of target vessel revascularization without differences in stroke or bleeding.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Ashkan Eftekhari, Tim P. van de Hoef, Masahiro Hoshino, Joo Myung Lee, Coen K. M. Boerhout, Guus A. de Waard, Ji-Hyun Jung, Seung Hun Lee, Hernan Mejia-Renteria, Mauro Echavarria-Pinto, Martijn Meuwissen, Hitoshi Matsuo, Maribel Madera-Cambero, Mohamed A. Effat, Koen Marques, Joon-Hyung Doh, Rupak Banerjee, Chang-Wook Nam, Giampaolo Niccoli, Tadashi Murai, Masafumi Nakayama, Nobuhiro Tanaka, Eun-Seok Shin, Paul Knaapen, Niels van Royen, Javier Escaned, Bon Kwon Koo, Steven A. J. Chamuleau, Tsunekazu Kakuta, Jan J. Piek, Evald Hoj Christiansen
Summary: This study investigated the association between changes in microvascular resistance (MR) and target vessel failure (TVF) in patients undergoing percutaneous coronary intervention (PCI). The results showed that increased MR post-PCI was associated with lesions of less severe hemodynamic influence at baseline and higher rates of TVF at follow-up.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Zaheer Alisiddiq, Harish Sharma, James Cotton, Lampson Fan
Summary: Coronary physiological measurements have revolutionized the treatment of coronary artery disease, allowing for more precise and tailored therapy. Pressure wire guided revascularization has proven to be effective in influencing clinical outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Alexander G. Truesdell, Mirvat A. Alasnag, Prashant Kaul, Syed Tanveer Rab, Robert F. Riley, Michael N. Young, Wayne B. Batchelor, Akiko Maehara, Frederick G. Welt, Ajay J. Kirtane, ACC Interventional Counci
Summary: Coronary angiography has been the standard for diagnosing coronary artery disease and guiding percutaneous coronary intervention (PCI). Intravascular imaging (IVI) technologies are used in conjunction with angiography to better assess plaque morphology and optimize PCI. IVI has utility in preintervention assessment, procedural guidance, and postintervention evaluation. IVI's role in reducing major adverse cardiac events in complex lesions is emerging, and further studies are underway. This paper provides an overview of available IVI technologies, reviews evidence supporting their use in PCI, and advocates for broader utilization.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Bahadir Simsek, Farouc A. Jaffer, Spyridon Kostantinis, Judit Karacsonyi, Hideki Koike, Darshan Doshi, Khaldoon Alaswad, Sevket Gorgulu, Omer Goktekin, Jaikirshan Khatri, Paul Poommipanit, Oleg Krestyaninov, Rhian Davies, Ahmed ElGuindy, Brian K. Jefferson, Taral Patel, Mitul Patel, Stephane Rinfret, Wissam A. Jaber, William Nicholson, Nidal Abi Rafeh, Ufuk Yildirim, Korhan Soylu, Salman Allana, Bavana V. Rangan, Olga C. Mastrodemos, Yader Sandoval, M. Nicholas Burke, Emmanouil S. Brilakis
Summary: This study investigated the impact of preprocedural coronary computed tomography angiography (CCTA) on chronic total occlusion (CTO) percutaneous coronary intervention (PCI). It was found that while CCTA may assist in procedural planning, there were no significant differences in technical success and major adverse cardiovascular events between cases with or without CCTA.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Stephanie M. Spehar, Milan Seth, Peter Henke, Khaldoon Alaswad, Theodore Schreiber, Aaron Berman, John Syrjamaki, Omar E. Ali, Yousef Bader, David Nerenz, Hitinder Gurm, Devraj Sukul
Summary: The study found that Black patients had a higher risk of 90-day readmission and cumulative mortality following PCI compared with White patients. Associations were mediated by dual eligibility, community economic well-being, and traditional cardiovascular risk factors.
AMERICAN HEART JOURNAL
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Devraj Sukul, Hitinder S. Gurm
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Hitinder S. Gurm, George Hanna
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Renu Virmani, Aloke V. Finn, Matthew Kutyna, Yu Sato, Karen Meess, Cody Smith, Robert S. Chisena, Hitinder S. Gurm, Jon C. George
Summary: This study aims to assess the feasibility and treatment effect of pulsatile intravascular lithotripsy (PIVL) on calcified lesions in a cadaveric model of peripheral artery disease. The results show that PIVL treatment was successful and resulted in new fractures and luminal expansion of the vessels. Therefore, PIVL could be a promising new approach for the treatment of vascular calcification.
CARDIOVASCULAR REVASCULARIZATION MEDICINE
(2023)
Article
Surgery
Chloe A. Powell, Jeremy Albright, Jacob Culver, Nicholas H. Osborne, Matthew A. Corriere, Devraj Sukul, Hitinder Gurm, Peter K. Henke
Summary: This study evaluates the impact of race and socioeconomic status on outcomes after lower extremity bypass surgery. Black patients and socioeconomically disadvantaged patients are more likely to present with severe CLTI, leading to increased risk of amputation and other complications after the surgery.
Article
Cardiac & Cardiovascular Systems
Brett. L. L. Wanamaker, Ahmad Shoaib, Milan Seth, Devraj Sukul, Mamas. A. A. Mamas, Hitinder. S. S. Gurm
Summary: This study compared data from PCI registries in the United States and the United Kingdom, and found significant differences between the two countries in terms of the prevalence of diabetes and other comorbidities, the proportion of primary PCI, adoption of transradial PCI, and trends in mechanical support utilization.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Engineering, Biomedical
Jessie Jingxuan Lyu, Yao Liu, Hitinder S. Gurm, Albert Shih, Yihao Zheng
Summary: A miniature grinding wheel was successfully fabricated for atherectomy to remove calcified plaques in coronary and peripheral arteries. The wheel was made by nickel-diamond electroplating on a thin, flexible hollow stainless steel drive shaft. Experimental validation showed that the wheel effectively removed the calcified plaque. This research could lead to a more effective and safer treatment device for lesions deep in coronary and peripheral arteries.
MEDICAL ENGINEERING & PHYSICS
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Hitinder S. Gurm, David E. Hamilton
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Hitinder S. Gurm, Nabeel Hyder
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Ashwini Kerkar, Devraj Sukul, Milan Seth, Michael A. Lauer, M. Chadi Alraies, Elizabeth Jane Pielsticker, Gerald C. Koenig, Mamas A. Mamas, Hitinder S. Gurm
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Francesco Moroni, Hitinder S. Gurm, Zachary Gertz, Antonio Abbate, Lorenzo Azzalini
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Proceedings Paper
Engineering, Biomedical
Robert S. Chisena, Hitinder Gurm, Albert J. Shih
Summary: Micro-computed tomography (μCT) is a powerful tool for generating three-dimensional images of objects using penetrative X-rays. It is useful for imaging hardened biological tissues and studying the efficacy of cardiovascular devices for the treatment of intravascular calcium (IVC). This article presents a generalized approach that utilizes μCT for qualitative and quantitative analyses of the treatment effect of new devices on IVC tissue.
V CIRP CONFERENCE ON BIOMANUFACTURING
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Brett Wanamaker, Ahmad Shoaib, Milan Seth, Devraj Sukul, A. Mamas Mamas, Hitinder S. Gurm
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Stephanie Spehar, Devraj Sukul, Hitinder S. Gurm, Milan Seth
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Daniel Kobe, Milan Seth, David Hamilton, Manoj Sharma, Douglas J. Wunderly, David Alan Sutter, Ronald V. Miller, Thomas A. LaLonde, Hitinder S. Gurm, Devraj Sukul
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Xiaoxi Yao, Zachi I. Attia, Emma M. Behnken, Melissa S. Hart, Shealeigh A. Inselman, Kayla C. Weber, Fan Li, Nikki H. Stricker, John L. Stricker, Paul A. Friedman, Peter A. Noseworthy
Summary: This study aims to explore whether Apple Watch, used as a long-term monitoring device, is effective in the early diagnosis of atrial fibrillation (AF) and the prevention of cognitive function decline in older adults. By using AI-ECG to screen high-risk patients and record electrocardiograms, the effectiveness of Apple Watch will be evaluated. If successful, this approach could have significant implications on how future clinical practice leverages consumer devices for early diagnosis and disease prevention.
AMERICAN HEART JOURNAL
(2024)