Article
Nutrition & Dietetics
Mesut Gumussoy, Volkan Atmis, Ahmet Yalcin, Remzi Bahsi, Seher Yigit, Sinan Ari, Haydar Can Dokuyan, Melih Gaffar Gozukara, Kamile Silay
Summary: This study evaluated the relationship between Malnutrition-sarcopenia syndrome (MSS) and all-cause mortality in hospitalised older Turkish people over two years. The results showed that MSS, sarcopenia, sarcopenia with malnutrition risk, and malnutrition groups were independently associated with higher mortality rates. MSS group had the highest hazard ratio and the worst survival curve among the study groups. Measures to prevent both sarcopenia and malnutrition are needed to reduce adverse health outcomes such as mortality in hospitalized older individuals.
CLINICAL NUTRITION
(2021)
Article
Geriatrics & Gerontology
Yun-Ting Huang, Andrew Steptoe, Li Wei, Paola Zaninotto
Summary: This study investigated the association between different levels of polypharmacy and mortality among older adults. The results showed that both polypharmacy and heightened polypharmacy were related to all-cause mortality and cardiovascular disease deaths. Heightened polypharmacy was also related to cancer mortality. The study suggests that greater attention to polypharmacy in general for older people may reduce adverse effects and improve their health.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Nutrition & Dietetics
Xiaoxiao Wang, Youyou Ying, Minyue Pei, Xinjie Ma, Yuehao Sun, Yupeng Wang, Nan Li
Summary: This study found that long-term monitoring of calf circumference changes is associated with mortality. Participants with stable calf circumference had the lowest risk of death. These findings highlight the practical significance of monitoring calf circumference change in older adults.
CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Tagrid Alharbi, Joanne Ryan, Rosanne Freak-Poli, Danijela Gasevic, Jacqueline Scali, Karen Ritchie, Marie-Laure Ancelin, Alice J. Owen
Summary: Changes in body weight in older adults may be associated with increased mortality risk. Significant weight loss of 5% or more is linked to higher all-cause and cardiovascular disease mortality risk, while weight gain does not increase mortality risk.
Article
Endocrinology & Metabolism
Xia Shen, Long Yang, Xue Gu, Yuan-Yuan Liu, Lei Jiang
Summary: This study examined the relationship between malnutrition, as defined by the Geriatric Nutrition Risk Index (GNRI), and all-cause mortality and cardiovascular mortality events in older Americans with diabetes. It found that lower GNRI levels were associated with mortality in older patients with diabetes, and GNRI may be a predictor of all-cause mortality and cardiovascular mortality risk in this population.
DIABETOLOGY & METABOLIC SYNDROME
(2023)
Article
Cardiac & Cardiovascular Systems
Dong Hoon Lee, Leandro F. M. Rezende, Hee-Kyung Joh, NaNa Keum, Gerson Ferrari, Juan Pablo Rey-Lopez, Eric B. Rimm, Fred K. Tabung, Edward L. Giovannucci
Summary: Engaging in moderate or vigorous physical activities for an appropriate amount of time can reduce the risk of mortality.
Article
Geriatrics & Gerontology
Anhang Zhang, Yingnan Li, Shouyuan Ma, Qiligeer Bao, Jin Sun, Shuang Cai, Man Li, Yongkang Su, Bokai Cheng, Jing Dong, Yan Zhang, Shuxia Wang, Ping Zhu
Summary: This study aimed to determine the predictive ability of the Conicity-index (C-index) for all-cause mortality among non-cancer Chinese older people. The results showed a clear dose-response relationship between C-index and all-cause mortality, indicating that C-index is an independent risk factor for all-cause mortality in this population.
Article
Medicine, General & Internal
Adrian Carballo-Casla, Rosario Ortola, Esther Garcia-Esquinas, Andreia Oliveira, Mercedes Sotos-Prieto, Carla Lopes, Esther Lopez-Garcia, Fernando Rodriguez-Artalejo
Summary: The study shows that higher adherence to the Southern European Atlantic Diet (SEAD) is associated with lower all-cause mortality in older adults, with moderate wine consumption being particularly beneficial. The protective association between SEAD and all-cause death is similar to that of the Mediterranean Diet Adherence Screener and the Alternate Healthy Eating Index.
Article
Endocrinology & Metabolism
Yidan Guo, Ru Tian, Pengpeng Ye, Xin Li, Guogang Li, Fangping Lu, Yingchun Ma, Yi Sun, Yuzhu Wang, Yuefei Xiao, Qimeng Zhang, Xuefeng Zhao, Haidan Zhao, Yang Luo
Summary: A study found that cognitive impairment is associated with all-cause mortality in hemodialysis patients, especially in the executive and memory cognitive domains. These findings suggest that detecting impairments in these cognitive domains may help in the early identification of hemodialysis patients at risk of death.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Geriatrics & Gerontology
Neil A. Kelly, Orysya Soroka, Chukwuma Onyebeke, Laura C. Pinheiro, Samprit Banerjee, Monika M. Safford, Parag Goyal
Summary: Greater adherence to a healthy lifestyle was associated with lower all-cause mortality irrespective of medication burden and age.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Review
Biochemistry & Molecular Biology
Tais Boeira Biazus, Gabriel Henrique Beraldi, Lucas Tokeshi, Luisa de Siqueira Rotenberg, Elena Dragioti, Andre F. Carvalho, Marco Solmi, Beny Lafer
Summary: The results of this systematic review and meta-analysis show that the risk of premature death in patients with bipolar disorder is not only related to suicide and unnatural causes, but also to physical comorbidities. Therefore, in addition to suicide prevention, promoting physical health and preventing physical conditions in individuals with bipolar disorder may reduce premature mortality risk.
MOLECULAR PSYCHIATRY
(2023)
Article
Nutrition & Dietetics
Yu-Jin Kwon, Hye Sun Lee, Goeun Park, Juyeon Yang, Hyung-Mi Kim, Ji-Won Lee
Summary: This study investigated the association between dietary zinc intake and total deaths, cancer, and cardiovascular disease death. The results showed that dietary zinc intake was inversely associated with all-cause mortality and cardiovascular disease mortality, but not with cancer mortality. These findings suggest that recommending optimal dietary zinc intake is beneficial for human health.
Article
Public, Environmental & Occupational Health
Moises H. Sandoval, Marcela Alvear Portaccio, Cecilia Albala
Summary: This study aimed to explore the association between soda participation and mortality risk in older adults in Chile. Using the Chilean National Survey on Elderly Dependency, which is connected to vital statistics, death records were obtained. Four proportional risk regression models were utilized. Taking into account sociodemographic, economic, family, and health variables, it was found that older adults who engaged in social activities had a 22% lower risk of death compared to those who did not participate. The study concluded that social participation is a significant and powerful protective factor for mortality in older adults in Chile. Therefore, promoting social participation from a life course perspective considering its impact on mortality in older adults who maintain an active social life.
CADERNOS DE SAUDE PUBLICA
(2022)
Article
Geriatrics & Gerontology
Janani Thillainadesan, Sarah J. Aitken, Sue R. Monaro, John S. Cullen, Richard Kerdic, Sarah N. Hilmer, Vasi Naganathan
Summary: This study evaluates the impact of a novel model of care called Geriatric Comanagement of Older Vascular surgery inpatients, showing a reduction in hospital-acquired geriatric syndromes and delirium after implementation, with more significant effects observed in frail patients.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Nutrition & Dietetics
Aishat T. Bakre, Anthony Chen, Xuguang Tao, Jian Hou, Yuyou Yao, Alain Nevill, James J. Tang, Sabine Rohrmann, Jindong Ni, Zhi Hu, John Copeland, Ruoling Chen
Summary: This study found that increased fish consumption in older adults can reduce all-cause mortality in those without dementia, but not in those with dementia. This suggests that increasing fish intake in old age may help prevent dementia and prolong life.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Dentistry, Oral Surgery & Medicine
Fredrick Alan Clive Wright, Ellie C. -C Shu, Robert G. Cumming, Vasi Naganathan, Fiona M. Blyth, Vasant Hirani, David G. Le Couteur, David J. Handelsman, Markus J. Seibel, Louise M. Waite, Fiona F. Stanaway
Summary: The study assessed the oral health-related quality of life in older Australian men and explored the association between their general health conditions, socio-demographic factors, and oral health-related quality of life. The results showed that older Australian men exhibited good oral health-related quality of life. The study also highlighted the inter-relationship between perceptions of general health and well-being, health and oral health variables, and social background, supporting the integration of general health and oral health services for older Australian men.
COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY
(2023)
Article
Geriatrics & Gerontology
Kim M. Kiely, Saman Khalatbari-Soltani, Fiona M. Blyth, Vasikaran Naganathan, David J. Handelsman, Louise M. Waite, David G. Le Couteur, Moyra E. Mortby, Robert G. Cumming, Kaarin J. Anstey
Summary: This study aimed to assess the association between self-reported hearing difficulties and future risk of falling among older adults. The findings from the two Australian cohorts showed mixed results, suggesting that self-reported hearing difficulties may be predictive of falls in some cases but not in others.
Article
Pharmacology & Pharmacy
Nashwa Masnoon, Sarita Lo, Sarah Hilmer
Summary: The study aims to determine the uptake and implementation of recommendations for deprescribing anticholinergic and sedative medications by the medical team, as well as the outcomes of these recommendations.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Rehabilitation
Nathalia Costa, Fiona M. Blyth, Sarika Parambath, Carmen Huckel Schneider
Summary: This study analyzed the discourse of Australian directives regarding low back pain (LBP) and found that LBP is represented as a symptom that improves when individuals take responsibility for themselves. The directives overlook important aspects like scientific uncertainties, alternative paradigms, multimorbidity, and social determinants of health.
DISABILITY AND REHABILITATION
(2023)
Article
Geriatrics & Gerontology
Esa Y. H. Chen, Jiaxi Zhao, Jenni Ilomaki, Janet K. Sluggett, J. Simon Bell, Barbara C. Wimmer, Sarah N. Hilmer, Joseph E. Blais, Ian C. K. Wong, Esther W. Chan
Summary: This study found that in patients with atrial fibrillation initiating oral anticoagulants, a more complex medication regimen was associated with a higher risk of bleeding, especially beyond 90 days of treatment.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Gizem Gemikonakli, John Mach, Fan Zhang, Martyn Bullock, Trang Tran, Emad El-Omar, Sarah N. Hilmer
Summary: This study found that aging, chronic polypharmacy, and deprescribing have different effects on the diversity and composition of the gut microbiome. The changes in the microbiome are associated with frailty and function.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Hamish Jamieson, Prasad S. Nishtala, Hans Ulrich Bergler, Susan K. Weaver, John W. Pickering, Nagham J. Ailabouni, Rebecca Abey-Nesbit, Carolyn Gullery, Joanne Deely, Susan B. Gee, Sarah N. Hilmer, Dee Mangin
Summary: Polypharmacy is linked to poor outcomes in older adults. Targeted deprescribing of anticholinergic and sedative medications may be beneficial for frail older adults. However, our pharmacist-led deprescribing intervention did not reduce the anticholinergic/sedative load among frail older participants within 6 months.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Tam Ngoc Nguyen, Tu Ngoc Nguyen, Janani Thillainadesan, Anh Trung Nguyen, Huong Thi Thu Nguyen, Thu Thi Hoai Nguyen, Huong Thi Thanh Nguyen, Thanh Xuan Nguyen, Vasi Naganathan, Huyen Thi Thanh Vu
Summary: This study investigates the relationship between sarcopenia and frailty and identifies factors associated with frailty among older patients, with and without sarcopenia.
AUSTRALASIAN JOURNAL ON AGEING
(2023)
Article
Nutrition & Dietetics
David Scott, Fiona Blyth, Vasi Naganathan, David G. Le Couteur, David J. Handelsman, Louise M. Waite, Vasant Hirani
Summary: This study examined the coexistence of obesity and sarcopenia in older men and found that the prevalence and functional outcomes of sarcopenic obesity varied depending on different consensus definitions. The results indicated that the operational definition of sarcopenic obesity by the European Society for Clinical Nutrition and Metabolism (ESPEN-EASO) could accurately identify the functional impairment risk in older obese men.
CLINICAL NUTRITION
(2023)
Article
Geriatrics & Gerontology
Rebecca Luong, R. V. Ribeiro, A. Rangan, V. Naganathan, F. Blyth, L. M. Waite, D. J. Handelsman, D. G. Le Couteur, M. J. Seibel, V. Hirani
Summary: This study evaluated the associations between dietary iron intake and major adverse cardiovascular events (MACE). It found that higher haem iron intake was associated with increased risks of five-point MACE, four-point MACE excluding all-cause mortality, all-cause mortality, congestive cardiac failure (CCF), and coronary revascularisation in older men over 5 years.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Gerontology
Kate H. Marshall, Diane L. Riddiford-Harland, Anne E. Meller, Gideon A. Caplan, Vasi Naganathan, John Cullen, Peter Gonski, Nicholas A. Zwar, Julie-Ann O'Keeffe, Karolina Krysinska, Joel J. Rhee
Summary: This study aimed to investigate the feasibility and acceptability of implementing a facilitated advance care planning (ACP) intervention for patients attending tertiary outpatient clinics. Results showed that patients in the intervention group expressed high satisfaction with the facilitated ACP session, while control group participants reported more difficulties. These findings suggest that embedding facilitated ACP into tertiary outpatient care is feasible and acceptable for patients with advanced illnesses.
JOURNAL OF APPLIED GERONTOLOGY
(2023)
