Article
Biochemistry & Molecular Biology
Takahiro Yamazaki, Sayuri Yamada, Konomi Ohshio, Miho Sugamata, Yuji Morita
Summary: Lactobacillus paracasei KW3110 has anti-inflammatory effects and prevents inflammatory stress-induced mitochondrial damage by promoting IL-10 production in mouse macrophages.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Allergy
Toshihiro Osada, Mitsuhiro Okano
Summary: The text discusses seasonal allergic diseases caused by pollen from tree species in the Cupressaceae family, focusing on the latest research findings, newly identified causative allergens, and treatments for Japanese cedar and Japanese cypress pollinosis.
ALLERGOLOGY INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Shoko Ueda, Jun Ito, Norihiro Harada, Sonoko Harada, Hitoshi Sasano, Yuuki Sandhu, Yuki Tanabe, Sumiko Abe, Satomi Shiota, Yuzo Kodama, Tetsutaro Nagaoka, Fumihiko Makino, Asako Chiba, Hisaya Akiba, Ryo Atsuta, Sachiko Miyake, Kazuhisa Takahashi
Summary: This study investigated the efficacy of sublingual immunotherapy (SLIT) in asthmatic patients with seasonal allergic rhinitis (SAR-JCP) and found that SLIT not only significantly improved allergic rhinitis and asthma symptoms, but also improved airway resistance. Moreover, the reduction in peripheral blood gamma delta T cells after SLIT was associated with the improvement of asthma symptoms.
Article
Food Science & Technology
Hua Jiang, Shengjie Tan, Ke Ning, Hao Li, Wenzhi Zhao, Ai Zhao, Hong Zhu, Shijie Wang, Peiyu Wang, Yumei Zhang
Summary: In this study, intervention with the probiotic LP N1115 in dyslipidemia patients resulted in lower levels of serum total cholesterol and apolipoprotein B, as well as improvements in glucose metabolism. Probiotic intervention also led to changes in certain components and diversity indices of the gut microbiota.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Biotechnology & Applied Microbiology
Bingyong Mao, Qunran Xiang, Xin Tang, Qiuxiang Zhang, Xiaoming Liu, Jianxin Zhao, Shumao Cui, Hao Zhang
Summary: This study found that Lactobacillus reuteri CCFM1175 and Lactobacillus paracasei CCFM1176 can effectively prevent CAP-induced intestinal injury and improve gastrointestinal health. By regulating the expression of TRPV1, increasing the level of short-chain fatty acids, and modulating the composition of gut microbiota, these two strains of lactic acid bacteria improve intestinal structure, reduce inflammation, and enhance anti-inflammatory capacity.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Review
Microbiology
Daiju Sakurai, Hiroki Ishii, Ayumi Shimamura, Daisuke Watanabe, Takaaki Yonaga, Tomokazu Matsuoka
Summary: The incidence of Japanese cedar pollinosis is increasing significantly in Japan. Allergen immunotherapy is the only fundamental treatment that modifies the natural course of allergic rhinitis and provides long-term remission. Sublingual immunotherapy has been developed and proven to have long-term efficacy and safety.
Article
Microbiology
Zsolt Boros, Mihai Horia Baies, Dan Cristian Vodnar, Calin Mircea Gherman, Silvia-Diana Borsan, Anamaria Cozma-Petrut, Menelaos Lefkaditis, Adriana Gyorke, Vasile Cozma
Summary: This study evaluated the antiparasitic effect of Lactobacillus casei ATCC 393 and L. paracasei CNCM on mice infected with Trichinella britovi. The results showed that treatment with these probiotics significantly reduced the number of adult parasites in the intestines of the mice. Female mice had better response to L. paracasei CNCM treatment compared to males.
Article
Biotechnology & Applied Microbiology
Noorshafadzilah Talib, Nurul Elyani Mohamad, Swee Keong Yeap, Chai Ling Ho, Mas Jaffri Masarudin, Suraini Abd-Aziz, Mira Nadiah Mohd Izham, Muganti Rajah Kumar, Yazmin Hussin, Noorjahan Banu Alitheen
Summary: This study evaluated the anti-diabetic potential of the isolated L. paracasei from Malaysian water kefir grains and found that it alleviated T2DM by regulating gene expression, suggesting its potential as a dietary supplement for T2DM.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Microbiology
B. Sophatha, R. Teanpaisan
Summary: This study investigates the effects of various factors on adhesion and aggregation abilities of Lactobacillus strains derived from the human oral cavity. It suggests that bacterial adhesion is strain-specific and may depend on its origin, while positive effects of amylase, lysozyme, Ca ions, and low pH on adhesion and aggregation abilities were found. These findings may be useful for selecting probiotic strains for oral health and the development of probiotic products.
Article
Pediatrics
Hanna Lee, Zailing Li, Britt Christensen, Yongmei Peng, Xiaonan Li, Olle Hernell, Bo Loennerdal, Carolyn M. Slupsky
Summary: Early childhood nutrition plays a crucial role in shaping the gut microbiota, with probiotics potentially mitigating some of the unfavorable metabolic impacts of formula-feeding by altering the microbiome structure.
FRONTIERS IN PEDIATRICS
(2022)
Article
Biotechnology & Applied Microbiology
Concetta Di Natale, Elena Lagreca, Valeria Panzetta, Marianna Gallo, Francesca Passannanti, Michele Vitale, Sabato Fusco, Raffaele Vecchione, Roberto Nigro, Paolo Netti
Summary: The intestinal microbiota, composed of various bacterial species and strains, plays a crucial role in immune system development and function. Probiotics, through modulation of the microbiota, offer potential in the pharmaceutical and healthcare market. Encapsulation strategies have shown promise in protecting probiotic viability, with a need for optimization to ensure stability.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Zhu Zeng, Yi Yang, Xinxin Zhong, Fangyin Dai, Shangwu Chen, Xiaoling Tong
Summary: This study investigated the beneficial effects of Lactobacillus paracasei strain L14 on type 2 diabetes mellitus (T2DM) rats. The preventive supplementation of strain L14 showed excellent anti-diabetic effects, reducing hyperglycemia, protecting pancreatic beta-cell and liver function, and improving dyslipidemia and inflammation. The strain also modulated the gut microbiota to alleviate gut dysbiosis. The whole-genome sequencing of L14 identified genes related to antioxidant systems and other beneficial microbial metabolites, highlighting its potential applications in functional food and pharmaceutical industries.
Article
Biochemistry & Molecular Biology
Feng Gao, Zhifeng Fang, Wenwei Lu
Summary: The study found that Lactobacillus casei 431 and Lactobacillus fermentum PCC can regulate the systemic immune response imbalance, with the direction of regulation by Lactobacillus fermentum PCC being closer to the control group. Additionally, these lactobacillus strains can restore dysbiosis in the upper respiratory tract microbial community structure induced by penicillin, although no significant change in alpha diversity was observed. RDA analysis revealed that both Lactobacillus casei 431 and Lactobacillus fermentum PCC groups were positively correlated with IL-17 and IL-1 alpha.
Article
Food Science & Technology
Paloma Oliveira da Cruz, Clarisse Jales de Matos, Yuri Mangueira Nascimento, Josean Fechine Tavares, Evandro Leite de Souza, Hemerson Iury Ferreira Magalhaes
Summary: This study evaluated the efficacy of fruit-derived Lactobacillus isolates in removing aflatoxin M-1 from a phosphate buffer solution. Both viable and non-viable cells of the isolates were capable of removing AFM(1), with L. plantarum 49 showing the highest retention capacity after washing. The findings suggest the potential application of these isolates in reducing AFM(1) levels in foods and feeds.
Article
Biotechnology & Applied Microbiology
Sung-Joon Mo, Bora Nam, Chu-Hyun Bae, Soo-Dong Park, Jae-Jung Shim, Jung-Lyoul Lee
Summary: This study demonstrates that endophytic lactic acid bacteria like HY7017 cultured in red ginseng extract can enhance immunity, increase white blood cell counts, and improve immune responses in macrophages and splenocytes.
FERMENTATION-BASEL
(2021)
