Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses

CD11b+ Myeloid Cells Are the Key Mediators of Th2 Cell Homing into the Airway in Allergic Inflammation

(2014) B. D. Medoff et al.   JOURNAL OF IMMUNOLOGY

Blood Monocyte Subsets Differentially Give Rise to CD103+ and CD103- Pulmonary Dendritic Cell Populations

(2014) C. Jakubzick et al.   JOURNAL OF IMMUNOLOGY

The Critical Role of Epithelial-Derived Act1 in IL-17- and IL-25-Mediated Pulmonary Inflammation

(2014) S. Swaidani et al.   JOURNAL OF IMMUNOLOGY

TSLP Conditions the Lung Immune Environment for the Generation of Pathogenic Innate and Antigen-Specific Adaptive Immune Responses

(2014) M. B. Headley et al.   JOURNAL OF IMMUNOLOGY

The Adaptor Protein CIKS/Act1 Is Essential for IL-25-Mediated Allergic Airway Inflammation

(2014) E. Claudio et al.   JOURNAL OF IMMUNOLOGY

Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells

(2014) N. A. Barrett et al.   JOURNAL OF IMMUNOLOGY

Basophils Orchestrate Chronic Allergic Dermatitis and Protective Immunity against Helminths

(2010) Caspar Ohnmacht et al.   IMMUNITY

CD11c depletion severely disrupts Th2 induction and development in vivo

(2010) Alexander T. Phythian-Adams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

(2010) Hamida Hammad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses

(2010) Steven A. Saenz et al.   NATURE

The T helper type 2 response to cysteine proteases requires dendritic cell–basophil cooperation via ROS-mediated signaling

(2010) Hua Tang et al.   NATURE IMMUNOLOGY

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune cell populations function as initiators and effectors in Th2 cytokine responses

(2010) Steven A. Saenz et al.   TRENDS IN IMMUNOLOGY

Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation

(2009) F. Perros et al.   ALLERGY

Decreased FOXP3 protein expression in patients with asthma

(2009) S. Provoost et al.   ALLERGY

Regulatory T cells in bronchial asthma

(2009) K. Ryanna et al.   ALLERGY

Dendritic Cell-Nerve Clusters Are Sites of T Cell Proliferation in Allergic Airway Inflammation

(2009) Tibor Z. Veres et al.   AMERICAN JOURNAL OF PATHOLOGY

Resolution of Allergic Inflammation and Airway Hyperreactivity Is Dependent upon Disruption of the T1/ST2–IL-33 Pathway

(2009) Jennifer Kearley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Toll/IL-1 Signaling Is Critical for House Dust Mite–specific Th1 and Th2 Responses

(2009) Simon Phipps et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Thymic stromal lymphopoietin is a critical mediator of IL-13-driven allergic inflammation

(2009) Masanori Miyata et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

Selective control of SIRP-α–positive airway dendritic cell trafficking through CD47 is critical for the development of TH2-mediated allergic inflammation

(2009) Marianne Raymond et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Innate immune responses of airway epithelium to house dust mite are mediated through β-glucan–dependent pathways

(2009) Amy T. Nathan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TH17-associated cytokines (IL-17A and IL-17F) in severe asthma

(2009) Wisam Al-Ramli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An Anti-Inflammatory Role for Plasmacytoid Dendritic Cells in Allergic Airway Inflammation

(2009) M. Kool et al.   JOURNAL OF IMMUNOLOGY

Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells

(2009) D. Prefontaine et al.   JOURNAL OF IMMUNOLOGY

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide–MHC class II complexes to CD4+ T cells

(2009) Tomohiro Yoshimoto et al.   NATURE IMMUNOLOGY

MHC class II–dependent basophil–CD4+ T cell interactions promote TH2 cytokine–dependent immunity

(2009) Jacqueline G Perrigoue et al.   NATURE IMMUNOLOGY

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

(2009) Caroline L Sokol et al.   NATURE IMMUNOLOGY

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

The danger within: endogenous danger signals, atopy and asthma

(2008) M. A. M. Willart et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system

(2008) Y. Kondo et al.   INTERNATIONAL IMMUNOLOGY

Contribution of CCR4 and CCR8 to antigen-specific TH2 cell trafficking in allergic pulmonary inflammation

(2008) Zamaneh Mikhak et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes

(2008) Claudia Jakubzick et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clearance of influenza virus from the lung depends on migratory langerin+CD11b−but not plasmacytoid dendritic cells

(2008) Corine H. GeurtsvanKessel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Division of labor between dendritic cell subsets of the lung

(2008) C H GeurtsvanKessel et al.   Mucosal Immunology

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

(2008) Aurelien Trompette et al.   NATURE

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One