Article
Allergy
Esra Yucel, Ayse Suleyman, Zeynep Hizli Demirkale, Nermin Guler, Zeynep Ulker Tamay, Cevdet Ozdemir
Summary: This study in Turkey found that during the COVID-19 lockdown, children with house dust mite-sensitized asthma experienced improvements in respiratory symptoms due to reduced respiratory tract infections and outdoor pollution. However, nasal symptoms worsened in allergic rhinitis patients with house dust mite-sensitized asthma during this period.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2021)
Article
Environmental Sciences
Anne Boudier, Iana Markevych, Benedicte Jacquemin, Michael J. Abramson, Simone Accordini, Bertil Forsberg, Elaine Fuertes, Judith Garcia-Aymerich, Joachim Heinrich, Ane Johannessen, Benedicte Leynaert, Isabelle Pin, Valerie Siroux
Summary: This study found that European adults who resided in areas with higher air pollution and less greenspace were more likely to have lower mental component of health-related quality of life (HRQOL), regardless of their asthma or rhinitis status.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Allergy
Denis Caillaud, Marion Keirsbulck, Charlotte Leger, Benedicte Leynaert
Summary: This study conducted a review of the effects of outdoor mold exposure on respiratory health in children and adults. The results showed an association between outdoor fungal exposure and asthma exacerbation in children, but other findings were inconsistent. Further research is needed to better understand the impact of molds on rhinitis, asthma exacerbations, and lung function.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Environmental Sciences
Christoph Muysers, Fabrizio Messina, Thomas Keil, Stephanie Roll
Summary: The subscreen package successfully identified significant subgrouping factors like younger mothers in the low SES group being associated with higher risk of asthma in their children, and teenagers in the low SES group having increased risks. Additionally, factors such as (parental) smoking or lack of contact with farm animals were identified as strong risk factors for rhinitis. The subscreen tool allows for comprehensive overview of odds ratios and disease proportions per subgroup in exploring the association between SES and respiratory allergies in childhood and youth.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Ruth J. Geller, Janice A. Espinola, Ronaldo C. Fabiano Filho, Kohei Hasegawa, Jonathan M. Mansbach, Ashley F. Sullivan, Carlos A. Camargo Jr
Summary: This study compared research definitions of childhood asthma based on parent-reported data. The strict asthma definition had the highest specificity and positive predictive value, while the flexible definition showed weaker associations with known asthma risk factors. The parent report of clinician-diagnosed asthma correlates well with known asthma risk factors.
ANNALS OF EPIDEMIOLOGY
(2021)
Article
Medicine, General & Internal
Marcel Mazur, Maria Czarnobilska, Wojciech Dyga, Ewa Czarnobilska
Summary: The prevalence of asthma and allergies among children and adolescents has been increasing in the past few decades. A study analyzing data from 2014 to 2018 found that over 40% of respondents reported allergic symptoms, with nearly 50% of them not diagnosed or treated. However, there has been a reduction in the frequency of asthma and allergic rhinitis cases, indicating a positive effect on preventive measures taken in Krakow since 2010.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Environmental Sciences
Pierpaolo Marchetti, Jessica Miotti, Francesca Locatelli, Leonardo Antonicelli, Sandra Baldacci, Salvatore Battaglia, Roberto Bono, Angelo Corsico, Claudio Gariazzo, Sara Maio, Nicola Murgia, Pietro Pirina, Camillo Silibello, Massimo Stafoggia, Lorena Torroni, Giovanni Viegi, Giuseppe Verlato, Alessandro Marcon
Summary: Long-term exposure to air pollution has adverse respiratory health effects. The study found associations between PM exposure and rhinitis and between NO2 exposure and CB/CO PD, while asthma was not related to environmental exposures.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Allergy
Johanna Heldin, Andrei Malinovschi, Ane Johannessen, Kjell Alving, Mathias Holm, Karl A. Franklin, Bertil Forsberg, Vivi Schlunssen, Rain Jogi, Thorarinn Gislason, Bryndis Benediktsdottir, Cecilie Svanes, Christer Janson
Summary: Clinical remission was observed in nearly half of asthma patients and one-third of allergic rhinitis patients. Factors such as age, asthma symptoms, and childhood environmental factors (such as living in rural areas) were found to influence the clinical remission of allergic rhinitis.
JOURNAL OF ASTHMA AND ALLERGY
(2022)
Review
Otorhinolaryngology
Wei Ming, Jingjing Zuo, Jibo Han, Jinhui Chen
Summary: The study found that preexisting allergic airway diseases did not tend to worsen the course of COVID-19, and the prevalence of allergic airway diseases was not associated with the severity of COVID-19 patients; however, it was significantly associated with a decreased mortality risk of COVID-19.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Dermatology
Marina Z. Z. Joel, Ryan Fan, William Damsky, Jeffrey M. M. Cohen
Summary: This study aimed to investigate the association between psoriasis and asthma and allergic rhinitis (AR). Data from the NIH All of US Research Program was used, including over 300,000 US adults. The study found that participants with psoriasis had significantly higher prevalence of asthma and AR compared to participants without psoriasis.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Allergy
Wanjun Wang, Jianhong Wang, Guihua Song, Hua Xie, Xiaoping Lin, Ruonan Chai, Rongfei Zhu, Yong He, Jun Tang, Junge Wang, Jinghua Yang, Lili Zhi, Lin Wu, Yan Jiang, Xiaoqin Zhou, Dongming Huang, Ning Wang, Rui Xu, Yuan Gao, Zhimin Chen, Jinling Liu, Xiaoli Han, Guolin Tan, Jinzhun Wu, Deyu Zhao, Jianjun Chen, Xiwei Zhang, Mengrong Li, Yuemei Sun, Yi Jiang, Weitian Zhang, Qianhui Qiu, Chuanhe Liu, Jie Yin, Guodong Hao, Huabin Li, Yongsheng Xu, Shaohua Chen, Hua Zhang, Shi Chen, Juan Meng, Dan Zeng, Wei Tang, Chuangli Hao, Jing Li, Nanshan Zhong
Summary: Little is known about the changes in allergen sensitization in China over the past decade due to environmental variations. This study found that house dust mites remain the most important allergen, but pollen sensitization has dramatically increased in northern China. The increases in sensitization to dust mites and the plant Artemisia desertorum are related to increases in humidity and planting area.
CLINICAL AND TRANSLATIONAL ALLERGY
(2022)
Article
Allergy
Ju Hee Han, Hyun Ji Lee, Hwa Jung Yook, Kyungdo Han, Ji Hyun Lee, Young Min Park
Summary: This study investigated the association between atopic disorders and migraine in the Korean population. The results showed that patients with atopic dermatitis, asthma, and allergic rhinitis had an increased risk of migraine compared to the control group. Furthermore, the risk of migraine was higher in patients with multiple atopic disorders.
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
(2023)
Article
Respiratory System
Marine Savoure, Jean Bousquet, Benedicte Leynaert, Adeline Renuy, Valerie Siroux, Marcel Goldberg, Marie Zins, Benedicte Jacquemin, Rachel Nadif
Summary: A population-based cohort study in France found that the prevalence of allergic rhinitis (AR) and non-allergic rhinitis (NAR) in adults was 28.0% and 10.9%, respectively. AR patients were more likely to have persistent and moderate-to-severe rhinitis, and those with a history of asthma and conjunctivitis had earlier onset and more severe symptoms. These findings provide new insights for the management of rhinitis and its comorbidities.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Respiratory System
Subhabrata Moitra, Anne-Elie Carsin, Michael J. Abramson, Simone Accordini, Andre F. S. Amaral, Josep Anto, Roberto Bono, Lidia Casas Ruiz, Isa Cerveri, Leda Chatzi, Pascal Demoly, Sandra Dorado-Arenas, Bertil Forsberg, Frank Gilliland, Thorarinn Gislason, Jose A. Gullon, Joachim Heinrich, Mathias Holm, Christer Janson, Rain Jogi, Francisco Gomez Real, Debbie Jarvis, Benedicte Leynaert, Dennis Nowak, Nicole Probst-Hensch, Jose Luis Sanchez-Ramos, Chantal Raherison-Semjen, Valerie Siroux, Stefano Guerra, Manolis Kogevinas, Judith Garcia-Aymerich
Summary: This study is the first to show that adults with asthma have a higher risk of developing obesity compared to those without asthma, especially among non-atopic individuals, those with longer disease duration, or those taking oral corticosteroids.
Article
Respiratory System
Bright Nwaru, Holly Tibble, Syed A. Shah, Rebecca Pillinger, Susannah McLean, Dermot P. Ryan, Hilary Critchley, David B. Price, Catherine M. Hawrylowicz, Colin R. Simpson, Ireneous N. Soyiri, Francis Appiagyei, Aziz Sheikh
Summary: The study found that the use of hormonal contraceptives may reduce the risk of severe asthma exacerbation in reproductive-age women with asthma, and longer duration of use was associated with better outcomes.
Article
Public, Environmental & Occupational Health
F. Torres-Bondia, J. de Batlle, L. Galvan, M. Buti, F. Barbe, G. Pinol-Ripoll
Summary: The study analyzed the prevalence trends of proton pump inhibitors (PPIs) usage in the Lleida Health Region from 2002 to 2015, finding particularly high usage rates in the elderly population. Comprehensive actions are needed to improve rational prescribing of PPIs, especially in high-risk populations.
Article
Environmental Sciences
Giulia Squillacioti, Anne-Elie Carsin, Valeria Bellisario, Roberto Bono, Judith Garcia-Aymerich
Summary: Residential greenness exposure has a positive impact on health by reducing oxidative stress in children, and physical activity does not mediate this association.
ENVIRONMENTAL RESEARCH
(2022)
Article
Psychiatry
X. Goldberg, G. Castano-Vinyals, A. Espinosa, A. Carreras, L. Liutsko, E. Sicuri, M. Foraster, C. O'Callaghan-Gordo, P. Dadvand, G. Moncunill, C. Dobano, B. Cortes, V Pleguezuelos, K. Straif, J. Garcia-Aymerich, R. de Cid, E. Cardis, M. Kogevinas
Summary: This study examined the factors related to depression and anxiety after the first outbreak in Spain. The findings showed that pre-existing mental health conditions were associated with the severity of COVID-19 disease and increased risk of severe depression and anxiety. Among those without prior mental health disorders, post-lockdown depression and anxiety were associated with household interpersonal conflicts and financial instability.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Article
Respiratory System
Subhabrata Moitra, Anne-Elie Carsin, Michael J. Abramson, Simone Accordini, Andre F. S. Amaral, Josep Anto, Roberto Bono, Lidia Casas Ruiz, Isa Cerveri, Leda Chatzi, Pascal Demoly, Sandra Dorado-Arenas, Bertil Forsberg, Frank Gilliland, Thorarinn Gislason, Jose A. Gullon, Joachim Heinrich, Mathias Holm, Christer Janson, Rain Jogi, Francisco Gomez Real, Debbie Jarvis, Benedicte Leynaert, Dennis Nowak, Nicole Probst-Hensch, Jose Luis Sanchez-Ramos, Chantal Raherison-Semjen, Valerie Siroux, Stefano Guerra, Manolis Kogevinas, Judith Garcia-Aymerich
Summary: This study is the first to show that adults with asthma have a higher risk of developing obesity compared to those without asthma, especially among non-atopic individuals, those with longer disease duration, or those taking oral corticosteroids.
Article
Geriatrics & Gerontology
Remi Gontie, Judith Garcia-Aymerich, Julia Jubany, Marina Bosque-Prous, Tivy Baron-Garcia, Helena Gonzalez-Casals, Gemma Drou-Roget, Anna Beringues, Albert Espelt
Summary: This study analysed the relationship between physical activity and the incidence of dementia in people aged 50 years or older without dementia in Europe. The results showed that frequent moderate physical activity is independently associated with a lower risk of dementia. The study also found that the risk of dementia is higher in individuals who rarely or never engage in moderate-to-vigorous physical activity.
AGING & MENTAL HEALTH
(2023)
Article
Critical Care Medicine
Stefano Guerra, Julie G. Ledford, Erik Melen, Iris Lavi, Anne-Elie Carsin, Debra A. Stern, Jing Zhai, Marta Vidal, Mariona Bustamante, Kenneth J. Addison, Renata G. Vallecillo, Dean Billheimer, Gerard H. Koppelman, Judith Garcia-Aymerich, Nathanael Lemonnier, Montserrat Fito, Carlota Dobano, Simon Kebede Merid, Inger Kull, Rosemary R. C. McEachan, John Wright, Leda Chatzi, Manolis Kogevinas, Daniela Porta, Silvia Narduzzi, Ferran Ballester, Ana Esplugues, Carlos Zabaleta, Amaia Irizar, Jordi Sunyer, Marilyn Halonen, Jean Bousquet, Fernando D. Martinez, Josep M. Anto
Summary: A study was conducted to screen circulating proteins in childhood asthma and investigate their association with the disease in a mouse model. It was found that creatine kinase (CK) was consistently associated with asthma, and this association was further supported by gene expression analysis and a mouse model experiment.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Medicine, General & Internal
Jessica Gonzalez, Maria Zuil, Ivan D. Benitez, David de Gonzalo-Calvo, Maria Aguilar, Sally Santisteve, Rafaela Vaca, Olga Minguez, Faty Seck, Gerard Torres, Jordi de Batlle, Silvia Gomez, Silvia Barril, Anna Moncusi-Moix, Aida Monge, Clara Gort-Paniello, Ricard Ferrer, Adrian Ceccato, Laia Fernandez, Ana Motos, Jordi Riera, Rosario Menendez, Dario Garcia-Gasulla, Oscar Penuelas, Gonzalo Labarca, Jesus Caballero, Carme Barbera, Antoni Torres, Ferran Barbe
Summary: This study provides a detailed description of the long-term clinical management and evolution of a cohort of critical COVID-19 survivors. The findings show that one-third of critically ill COVID-19 patients need to continue follow-up beyond 1 year, due to abnormalities on pulmonary function tests, chest CT, or persistent symptoms.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Andrea Zapater, Geoffroy Solelhac, Alicia Sanchez-de-la-Torre, Esther Gracia-Lavedan, Ivan David Benitez, Gerard Torres, Jordi De Batlle, Jose Haba-Rubio, Mathieu Berger, Jorge Abad, Joaquin Duran-Cantolla, Amaia Urrutia, Olga Mediano, Maria Jose Masdeu, Estrella Ordax-Carbajo, Juan Fernando Masa, Monica De la Pena, Merce Mayos, Ramon Coloma, Josep Maria Montserrat, Eusebi Chiner, Olga Minguez, Lydia Pascual, Anunciacion Cortijo, Dolores Martinez, Mireia Dalmases, Chi-Hang Lee, R. Doug McEvoy, Ferran Barbe, Raphael Heinzer, Manuel Sanchez-de-la-Torre, Spanish Sleep Network
Summary: The severity of OSA is assessed based on the AHI, which is insufficient for capturing the severity and consequences of the disease in CVDs. This study aimed to identify RP patterns that could help in predicting the risk of recurrent cardiovascular events in patients with ACS. The analysis revealed that specific RP components, characterized by different respiratory events, were associated with an increased risk of recurrent cardiovascular events in ACS patients.
FRONTIERS IN MEDICINE
(2022)
Article
Respiratory System
Osama Mahmoud, Raquel Granell, Gabriela P. Peralta, Judith Garcia-Aymerich, Deborah Jarvis, John Henderson, Jonathan Sterne
Summary: This study found that maternal perinatal BMI, birthweight, childhood lean and fat mass, and early-onset asthma were the most important factors influencing lung function in early adulthood.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Geriatrics & Gerontology
Laura Delgado-Ortiz, Ashley Polhemus, Alison Keogh, Norman Sutton, Werner Remmele, Clint Hansen, Felix Kluge, Basil Sharrack, Clemens Becker, Thierry Troosters, Walter Maetzler, Lynn Rochester, Anja Frei, Milo A. Puhan, Judith Garcia-Aymerich
Summary: This study examined the personal experiences of individuals living with walking impairment and identified seven themes describing the walking experience across different health conditions. A novel conceptual framework was proposed to guide patient-centered clinical practice, research, and public health.
Article
Medicine, Research & Experimental
Andrea Zapater, Esther Gracia-Lavedan, Gerard Torres, Olga Minguez, Lydia Pascual, Anunciacion Cortijo, Dolores Martinez, Ivan David Benitez, Jordi De Batlle, Mario Henriquez-Beltran, Jorge Abad, Joaquin Duran-Cantolla, Amaia Urrutia, Olga Mediano, Maria Jose Masdeu, Estrella Ordax-Carbajo, Juan Fernando Masa, Monica De la Pena, Merce Mayos, Ramon Coloma, Josep Maria Montserrat, Eusebi Chiner, Ferran Barbe, Manuel Sanchez-de-la-Torre
Summary: This study aims to explore the pathological pathways by which obstructive sleep apnea (OSA) promotes the risk of recurrent cardiovascular events (CVE) in patients with acute coronary syndrome (ACS). The study found that certain protein levels in the blood are significantly associated with the risk of recurrent CVE in ACS patients.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Environmental Sciences
Alberto Ruano-Ravina, Orlando Acosta, David Diaz Perez, Ciro Casanova, Valle Velasco, German Peces-Barba, Esther Barreiro, Ana Canas, Argelia Castano, Maria Jesus Cruz Carmona, Carmen Diego, Judith Garcia-Aymerich, Cristina Martinez, Maria Molina-Molina, Xavier Munoz, Francisco Javier Sanchez-Inigo, Cristina Candal-Pedreira
Summary: This study aims to assess the short-, medium-, and long-term respiratory health effects of exposure to volcanic emissions from the eruption in different population groups. The study will employ multiple designs, including a cohort study on the general population, highly exposed population, and childhood population, as well as a pre-post quasi-experimental study on subjects with previously diagnosed respiratory diseases. Information will be collected through personal interviews, biologic specimens, air pollution data, and medical records, among other methods, with a planned follow-up of five years.
ENVIRONMENTAL RESEARCH
(2023)
Editorial Material
Public, Environmental & Occupational Health
Josep M. Anto, Neil Pearce, Jeroen Douwes, Judith Garcia-Aymerich, Lucy Pembrey, Lorenzo Richiardi, Jordi Sunyer
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Respiratory System
Anne-Elie Carsin, Judith Garcia-Aymerich, Simone Accordini, Shyamali Dharmage, Benedicte Leynaert, Marti de las Heras, Lidia Casas, Seraina Caviezel, Pascal Demoly, Bertil Forsberg, Thorarinn Gislason, Angelo Guido Corsico, Christer Janson, Rain Jogi, Jesus Martinez-Moratalla, Dennis Nowak, Leopoldo Palacios Gomez, Isabelle Pin, Nicole Probst-Hensch, Chantal Raherison-Semjen, Giulia Squillacioti, Cecilie Svanes, Kjell Toren, Isabel Urrutia, Ismael Huerta, Josep Maria Anto, Debbie Jarvis, Stefano Guerra
Summary: This study aimed to describe the characteristics and risk factors of restrictive and obstructive spirometric patterns occurring before 40 years (young onset) and between 40 and 61 years (mid-adult onset). Data from the European Community Respiratory Health Survey (ECRHS) were used, and longitudinal assessments of forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) were conducted.
Article
Health Care Sciences & Services
Joren Buekers, Ane Arbillaga-Etxarri, Elena Gimeno-Santos, David Donaire-Gonzalez, Guillaume Chevance, Jean-Marie Aerts, Judith Garcia-Aymerich
Summary: This study aimed to determine if wearable devices could provide valid heart rate (HR) and oxygen uptake (V?O-2) kinetics during outdoor walks in patients with chronic obstructive pulmonary disease (COPD). The results showed that continuous measurements with wearable devices provided valid HR and V?O-2 kinetics, which were comparable to laboratory-based tests.