AIDS Vaccines and Preexposure Prophylaxis: Is Synergy Possible?

HIV viral set point and host immune control in individuals with HIV-specific CD8+ T-cell responses prior to HIV acquisition

(2010) Rupert Kaul et al.   AIDS

Weighing the gold in the gold standard: challenges in HIV prevention research

(2010) Nancy S Padian et al.   AIDS

Side effects of long-term oral antiviral therapy for hepatitis B

(2010) Robert J. Fontana   HEPATOLOGY

Low-Level Exposure to HIV Induces Virus-Specific T Cell Responses and Immune Activation in Exposed HIV-Seronegative Individuals

(2010) C. Restrepo et al.   JOURNAL OF IMMUNOLOGY

Cohorts for the Study of HIV‐1–Exposed but Uninfected Individuals: Benefits and Limitations

(2010) R. E. Horton et al.   JOURNAL OF INFECTIOUS DISEASES

A Limited Number of Simian Immunodeficiency Virus (SIV) env Variants Are Transmitted to Rhesus Macaques Vaginally Inoculated with SIVmac251

(2010) M. Stone et al.   JOURNAL OF VIROLOGY

Costs of eliminating HIV in South Africa have been underestimated

(2010) Bradley Wagner et al.   LANCET

Accelerating HIV vaccine development

(2010) Wayne C. Koff   NATURE

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

(2010) Q. Abdool Karim et al.   SCIENCE

Some design issues in phase 2B vs phase 3 prevention trials for testing efficacy of products or concepts

(2010) Peter B. Gilbert   STATISTICS IN MEDICINE

Genetic characterization of HIV-1 from semen and blood from clade C-infected subjects from India and effect of therapy in these body compartments

(2010) Chengli Shen et al.   VIROLOGY

Highly active antiretroviral treatment for the prevention of HIV transmission

(2010) Reuben Granich et al.   Journal of the International AIDS Society

Protection of macaques against vaginal SHIV challenge by systemic or mucosal and systemic vaccinations with HIV-envelope

(2009) Susan W Barnett et al.   AIDS

Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and meta-analysis

(2009) Suzanna Attia et al.   AIDS

Persistent HIV RNA shedding in semen despite effective antiretroviral therapy

(2009) Prameet M Sheth et al.   AIDS

Repeated Rectal SHIVSF162P3 Exposures Do Not Consistently Induce Sustained T Cell Responses Prior to Systemic Infection in the Repeat-Low Dose Preclinical Macaque Model

(2009) Ellen N. Kersh et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The Pharmacokinetics and Viral Activity of Tenofovir in the Male Genital Tract

(2009) Manoli Vourvahis et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Universal Voluntary Testing and Treatment for Prevention of HIV Transmission

(2009) Carl W. Dieffenbach   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Determining Seminal Plasma Human Immunodeficiency Virus Type 1 Load in the Context of Efficient Highly Active Antiretroviral Therapy

(2009) C. Pasquier et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1

(2009) Brandon F. Keele et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Initiation of Antiretroviral Therapy 48 Hours after Infection with Simian Immunodeficiency Virus Potently Suppresses Acute-Phase Viremia and Blocks the Massive Loss of Memory CD4+ T Cells but Fails To Prevent Disease

(2009) M. Kubo et al.   JOURNAL OF VIROLOGY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa

(2009) Etienne Karita et al.   PLoS One

Oral pre-exposure prophylaxis for HIV prevention

(2009) J. Gerardo García-Lerma et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Use of antiretrovirals during pregnancy and breastfeeding in low-income and middle-income countries

(2009) James McIntyre   Current Opinion in HIV and AIDS

The ‘immunologic advantage’ of HIV-exposed seronegative individuals

(2008) Masaaki Miyazawa et al.   AIDS

Short Communication: No Evidence of Occult SHIV Infection as Demonstrated by CD8+ Cell Depletion after Chemoprophylaxis-Induced Protection from Mucosal Infection in Rhesus Macaques

(2008) Ellen N. Kersh et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Less is more, except when less is less: Studying joint effects

(2008) C.R. Weinberg   GENOMICS

Drug-Susceptible HIV-1 Infection Despite Intermittent Fixed-Dose Combination Tenofovir/Emtricitabine as Prophylaxis Is Associated With Low-Level Viremia, Delayed Seroconversion, and an Attenuated Clinical Course

(2008) Nicole Prada et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Expanded Access to Highly Active Antiretroviral Therapy: A Potentially Powerful Strategy to Curb the Growth of the HIV Epidemic

(2008) Viviane D. Lima et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Can antiretroviral therapy eliminate HIV transmission?

(2008) Kevin M De Cock et al.   LANCET

Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model

(2008) Reuben M Granich et al.   LANCET

Challenges in the development of an HIV-1 vaccine

(2008) Dan H. Barouch   NATURE

Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans

(2008) David I Watkins et al.   NATURE MEDICINE

The Impact of Pre-Exposure Prophylaxis (PrEP) on HIV Epidemics in Africa and India: A Simulation Study

(2008) Debby C. J. Vissers et al.   PLoS One

Reference Intervals in Healthy Adult Ugandan Blood Donors and Their Impact on Conducting International Vaccine Trials

(2008) Leigh Anne Eller et al.   PLoS One

Toward an AIDS Vaccine

(2008) B. D. Walker et al.   SCIENCE

Mucosal prior to systemic application of recombinant adenovirus boosting is more immunogenic than systemic application twice but confers similar protection against SIV-challenge in DNA vaccine-primed macaques

(2008) Reiner Schulte et al.   VIROLOGY

Prevention of Rectal SHIV Transmission in Macaques by Daily or Intermittent Prophylaxis with Emtricitabine and Tenofovir

(2008) J. Gerardo García-Lerma et al.   PLOS MEDICINE

Prevention of SIV Rectal Transmission and Priming of T Cell Responses in Macaques after Local Pre-exposure Application of Tenofovir Gel

(2008) Martin Cranage et al.   PLOS MEDICINE