Article
Geriatrics & Gerontology
Amatul Marium, Ayobami S. Ogunsola, Udeh C. Mercy, Ifedioranma Anikpo, Maryam A. Sa'id, Rukayyah M. Karaye, Aishatu Yusuf, Eniola A. Olatunji, Ismaeel Yunusa, Ibraheem M. Karaye
Summary: This study analyzed the trends in HIV-related mortality among US citizens aged 65 years and above, and found that overall HIV mortality rates have increased from 1999 to 2020, with varying trends among different races and ethnicities. This highlights the importance of strengthened public health surveillance to better understand the scope of HIV mortality among older adults and to identify high-risk demographic groups for targeted interventions. Improving timely diagnosis, managing comorbidities, and reducing stigma surrounding HIV among older adults are crucial to reducing HIV mortality in this population.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Oncology
Lauren Greenberg, Lene Ryom, Elzbieta Bakowska, Ferdinand C. Wit, Heiner C. L. Bucher, Dominique L. Braun, Andrew Phillips, Caroline Sabin, Antonella d'Arminio Monforte, Robert Zangerle, Colette Smith, Stephane De Wit, Fabrice Bonnet, Christian Pradier, Cristina Mussini, Camilla Muccini, Joerg J. Vehreschild, Jennifer Hoy, Veronica M. Svedhem, Jose M. Miro, Jan-Christian Wasmuth, Peter M. Reiss, Josep M. Llibre, Nikoloz Chkhartishvili, Christoph I. Stephan, Camilla Hatleberg, Bastian Neesgaard, Lars Peters, Nadine Jaschinski, Nikos Dedes, Elena Kuzovatova, Marc Van Der Valk, Marianna Menozzi, Clara Lehmann, Kathy Petoumenos, Harmony Garges, Jim Rooney, Lital D. Young, Jens D. Lundgren, Loveleen Bansi-Matharu, Amanda Mocroft, RESPOND D A D Study Grp
Summary: Cancer incidence rates remained stable overall from 2006 to 2021, but there were changes in the rates of specific types of cancer among people with HIV. AIDS-defining cancers and infection-related cancers decreased, while non-AIDS-defining cancers, smoking-related cancers, and BMI-related cancers increased. These findings emphasize the importance of prevention strategies for reducing the incidence of non-AIDS-defining cancers, smoking-related cancers, and BMI-related cancers.
Article
Public, Environmental & Occupational Health
Maeve E. Wallace
Summary: The rate of pregnancy-associated homicides in 2020 increased significantly, particularly among adolescents and non-Hispanic Black women. Most incidents involved firearms. Pregnant and postpartum women had a 35% higher risk of homicide compared to their nonpregnant counterparts.
AMERICAN JOURNAL OF PUBLIC HEALTH
(2022)
Article
Oncology
Cameron B. Haas, Eric A. Engels, Marie-Josephe Horner, Ruth M. Pfeiffer, Qianlai Luo, Aimee R. Kreimer, Joel M. Palefsky, Meredith S. Shiels
Summary: Treatment of screen-detected anal high-grade squamous intraepithelial lesions effectively reduces incidence of invasive anal cancer in people with HIV. Men who have sex with men are at the greatest risk, especially those with a diagnosis of AIDS. These estimates can guide prioritization of anal cancer screening and treatment.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Public, Environmental & Occupational Health
Jacob Bleasdale, Yu Liu, Lucia A. Leone, Gene D. Morse, Sarahmona M. Przybyla
Summary: This study aims to examine the impact mechanisms of food insecurity on the progress made by people living with HIV (PLWHA) in healthcare. The results show that food insecurity is associated with increased likelihood of poor retention in care and viral non-suppression. Furthermore, the study found that nutritional and mental health pathways are important mediators of this relationship. Therefore, interventions targeting these pathways are needed to address the impact of food insecurity on engagement in HIV care.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Pediatrics
Margaret A. Lampe, Steven R. Nesheim, Keydra L. Oladapo, Alexander C. Ewing, Jeffrey Wiener, Athena P. Kourtis
Summary: In 2012, the Centers for Disease Control and Prevention set goals for the elimination of perinatal transmission of HIV in the United States. Data from the National HIV Surveillance System shows a decrease in the number of perinatally acquired HIV cases and perinatal HIV diagnosis rates from 2010 to 2019. Racial and ethnic disparities in HIV diagnosis rates have also significantly declined over the 10-year period. The achievement of elimination goals in 2019 highlights the importance of continued coordinated efforts in healthcare and public health to maintain the elimination of perinatal HIV and eliminate racial disparities.
Article
Psychology, Multidisciplinary
Xiaoyu Du, Qian Zhang, Jiaqi Hao, Xilong Gong, Jing Liu, Jia Chen
Summary: This study utilizes bibliometric analysis to investigate the research on depression related to HIV/AIDS. The findings reveal that HIV-related depression significantly affects the quality of life and treatment outcomes of individuals living with HIV. Key contributors in this field include the United States, South Africa, and the United Kingdom, and major topics of research include adherence to antiretroviral therapy, mental health, substance abuse, stigma, and the situation in Sub-Saharan Africa.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Medicine, General & Internal
Orly Termeie, Lawrence Fiedler, Lisa Martinez, Jennifer Foster, Parvathi Perumareddi, Robert S. Levine, Charles H. Hennekens
Summary: This study compared the trends in mortality from alcoholic cirrhosis in the United States between 1999 and 2019 using data from the CDC. The results showed a significant increase in the mortality rate of alcoholic cirrhosis, which may be attributed to heavy alcohol consumption and the obesity epidemic. Further research and intervention are needed to address these alarming trends.
AMERICAN JOURNAL OF MEDICINE
(2022)
Article
Immunology
Kartavya J. Vyas, Vincent C. Marconi, Abeer Moanna, David Rimland, Jodie L. Guest
Summary: The causes of death and their trends among veterans with HIV are different from those in the general population, and these differences have been observed in different eras of combination antiretroviral therapy. Veterans with HIV continue to have higher mortality rates compared to the general population in terms of AIDS-related infections, non-AIDS-related malignancies, respiratory disease, cardiovascular disease, and renal failure.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
(2023)
Article
Multidisciplinary Sciences
Md. Tariqujjaman, Md. Mehedi Hasan, Mohammad Abdullah Heel Kafi, Md. Alamgir Hossain, Saad Khan, Nadia Sultana, Rashidul Azad, Md. Arif Hossain, Mahfuzur Rahman, Mohammad Bellal Hossain
Summary: The proportion of low HIV knowledge among ever-married women of reproductive age in Bangladesh has decreased from 1996 to 2014, although it still remains high. Prevention of early marriage, inclusion of HIV-related topics in the curriculum, and reducing urban-rural and wealth disparities may help improve HIV knowledge among ever-married Bangladeshi women.
Review
Biochemistry & Molecular Biology
Zodwa Dlamini, Mzwandile Mbele, Tshepiso J. Makhafola, Rodney Hull, Rahaba Marima
Summary: Globally, HIV/AIDS and cancer are significant public health problems, with sub-Saharan Africa bearing the largest burden. While AIDS-defining cancers are decreasing, non-AIDS defining cancers are on the rise in HIV-positive individuals.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Multidisciplinary Sciences
Lorena Segarra, Samuel J. Simmens, Amanda D. Castel, Michael Kharfen, Henry Masur, Alan E. Greenberg
Summary: The Ending the HIV Epidemic (EHE) initiative in the U.S. has become a focal point for domestic HIV prevention and treatment programs, with analysis showing varying rates of decline in HIV diagnosis rates across the 57 high incidence hotspots. Higher initial HIV diagnosis rates and location in the Northeast region were significantly associated with declining rates, emphasizing the need for further exploration on the correlation between program factors and HIV trends in hotspots.
Article
Public, Environmental & Occupational Health
Megan Swanson, Amy Pickrel, John Williamson, Susan Montgomery
Summary: This report reveals a significant increase in babesiosis incidence in the northeastern states of the United States from 2011 to 2019. In addition to the known endemic areas, three states (Maine, New Hampshire, and Vermont) that were not considered to have endemic transmission also experienced a significant increase in incidence, with case counts similar to or higher than the seven known endemic states. Public health practice should focus on strengthening tick prevention messaging, provider education, and traveler risk awareness.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2023)
Article
Medicine, General & Internal
Boyoung Park, Kyoung Hwan Ahn, Yunsu Choi, Jung Ho Kim, Hye Seong, Youn Jeong Kim, Jun Young Choi, Joon Young Song, Eunjung Lee, Yoon Hee Jun, Young Kyung Yoon, Won Suk Choi, Myungsun Lee, Jaehyun Seong, Shin-Woo Kim
Summary: This study examined the cancer incidence and risk among HIV-infected individuals in Korea compared to the general population. The findings showed an increased risk of cancer, particularly AIDS-defining and virus-related cancers, in people with HIV. Efforts to improve cancer prevention, screening, and healthcare accessibility for HIV-infected individuals are necessary.
Article
Public, Environmental & Occupational Health
Zhihui Dou, Yanan Luo, Yan Zhao, Xiaoying Zheng, Mengjie Han
Summary: This report provides detailed information on the reported rate, mortality rate, and prevalence rate trends of HIV, AIDS, and HIV/AIDS in China's entire population over the past two decades for the first time, overcoming the longstanding limitation of analyzing HIV/AIDS as the sole denominator by incorporating a comprehensive examination of the overall population using indicators and analytic methods from chronic disease analyses.
Article
Oncology
Hilary A. Robbins, Christine D. Berg, Li C. Cheung, Anil K. Chaturvedi, Hormuzd A. Katki
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2019)
Article
Oncology
Hilary A. Robbins, Hormuzd A. Katki, Li C. Cheung, Rebecca Landy, Christine D. Berg
JOURNAL OF THORACIC ONCOLOGY
(2019)
Editorial Material
Critical Care Medicine
Hilary A. Robbins, Matthew Callister, Peter Sasieni, Samantha L. Quaife, Li C. Cheung, Paul Brennan, Hormuzd A. Katki, Christine D. Berg, David Baldwin, Mattias Johansson
LANCET RESPIRATORY MEDICINE
(2019)
Letter
Oncology
Hilary A. Robbins, Mattias Johansson
Editorial Material
Respiratory System
David R. Baldwin, Matthew E. Callister, Philip A. Crosbie, Emma L. O'Dowd, Robert C. Rintoul, Hilary A. Robbins, Robert J. C. Steele
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Oncology
Rebecca Landy, Corey D. Young, Martin Skarzynski, Li C. Cheung, Christine D. Berg, M. Patricia Rivera, Hilary A. Robbins, Anil K. Chaturvedi, Hormuzd A. Katki
Summary: The draft 2020 USPSTF guidelines increased eligibility for lung cancer screening among minorities and Whites by similar proportions compared to the 2013 guidelines. However, the relative disparity in gainable life-years from screening between eligible Whites and minorities actually increased with the 2020 guidelines. Using the LYFS-CT model could help reduce disparities in screening eligibility by identifying high-benefit individuals regardless of race and ethnicity.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Article
Oncology
Hilary A. Robbins, Karine Alcala, Anthony J. Swerdlow, Minouk J. Schoemaker, Nick Wareham, Ruth C. Travis, Philip A. J. Crosbie, Matthew Callister, David R. Baldwin, Rebecca Landy, Mattias Johansson
Summary: In UK cohorts, the ability of risk prediction models to classify future lung cancer cases as eligible for screening was best for LCDRAT/LCRAT, very good for PLCOm2012, and lowest for LLPv2. This highlights the importance of validating prediction tools in specific countries.
BRITISH JOURNAL OF CANCER
(2021)
Correction
Oncology
Hilary A. Robbins, Karine Alcala, Anthony J. Swerdlow, Minouk J. Schoemaker, Nick Wareham, Ruth C. Travis, Philip A. J. Crosbie, Matthew Callister, David R. Baldwin, Rebecca Landy, Mattias Johansson
BRITISH JOURNAL OF CANCER
(2021)
Article
Oncology
Hilary A. Robbins, Aida Ferreiro-Iglesias, Tim Waterboer, Nicole Brenner, Mari Nygard, Noemi Bender, Lea Schroeder, Allan Hildesheim, Michael Pawlita, Gypsyamber D'Souza, Kala Visvanathan, Hilde Langseth, Nicolas F. Schlecht, Lesley F. Tinker, Ilir Agalliu, Sylvia Wassertheil-Smoller, Eivind Ness-Jensen, Kristian Hveem, Sara Grioni, Rudolf Kaaks, Maria-Jose Sanchez, Elisabete Weiderpass, Graham G. Giles, Roger L. Milne, Qiuyin Cai, William J. Blot, Wei Zheng, Stephanie J. Weinstein, Demetrius Albanes, Wen-Yi Huang, Neal D. Freedman, Aimee R. Kreimer, Mattias Johansson, Paul Brennan
Summary: Seropositivity for HPV16-E6 oncoprotein is a promising marker for early detection of oropharyngeal cancer (OPC), but the absolute risk of OPC after a positive or negative test is unknown. This study constructed an OPC risk prediction model and found that a substantial proportion of HPV16-E6 seropositive individuals will develop OPC.
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Hilary A. Robbins, Karine Alcala, Elham Khodayari Moez, Florence Guida, Sera Thomas, Hana Zahed, Matthew T. Warkentin, Karl Smith-Byrne, Yonathan Brhane, David Muller, Xiaoshuang Feng, Demetrius Albanes, Melinda C. Aldrich, Alan A. Arslan, Julie Bassett, Christine D. Berg, Qiuyin Cai, Chu Chen, Michael P. A. Davies, Brenda Diergaarde, John K. Field, Neal D. Freedman, Wen-Yi Huang, Mikael Johansson, Michael Jones, Woon-Puay Koh, Stephen Lam, Qing Lan, Arnulf Langhammer, Linda M. Liao, Geoffrey Liu, Reza Malekzadeh, Roger L. Milne, Luis M. Montuenga, Thomas Rohan, Howard D. Sesso, Gianluca Severi, Mahdi Sheikh, Rashmi Sinha, Xiao-Ou Shu, Victoria L. Stevens, Martin C. Tammemaegi, Lesley F. Tinker, Kala Visvanathan, Ying Wang, Renwei Wang, Stephanie J. Weinstein, Emily White, David Wilson, Jian-Min Yuan, Xuehong Zhang, Wei Zheng, Christopher I. Amos, Paul Brennan, Mattias Johansson, Rayjean J. Hung
Summary: The INTEGRAL program aims to develop tools for optimizing LDCT lung cancer screening. It includes the Risk Biomarker and Nodule Malignancy projects, which investigate circulating protein markers for identifying individuals likely to benefit from screening and distinguishing benign versus malignant nodules. A total of 1161 and 1078 proteins were measured, and 21 proteins were selected for performance evaluation in the Risk Biomarker and Nodule Malignancy projects.
ANNALS OF EPIDEMIOLOGY
(2023)
Article
Oncology
Wendy Yi-Ying Wu, Zahra Haider, Xiaoshuang Feng, Alicia K. Heath, Anne Tjonneland, Antonio Agudo, Giovanna Masala, Hilary A. Robbins, Maria-Jose Huerta, Marcela Guevara, Matthias B. Schulze, Miguel Rodriguez-Barranco, Paolo Vineis, Rosario Tumino, Rudolf Kaaks, Renee T. Fortner, Sabina Sieri, Salvatore Panico, Therese Haugdahl Nost, Torkjel M. Sandanger, Tonje Braaten, Mattias Johansson, Beatrice Melin, Mikael Johansson
Summary: The study evaluated the risk-discriminatory performance of the EarlyCDT-Lung test in ever-smokers and found that it is not effective in identifying high-risk individuals for lung cancer screening.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Mahdi Sheikh, Anush Mukeriya, Hana Zahed, Xiaoshuang Feng, Hilary A. Robbins, Oxana Shangina, Vsevolod Matveev, Paul Brennan, David Zaridze
Summary: This study investigated the impact of smoking cessation after RCC diagnosis on the risk of death and disease progression. The results showed that quitting smoking was associated with lower risks of all-cause mortality, disease progression, and cancer-specific mortality among patients with RCC. This highlights the importance of smoking cessation in improving survival and reducing the risk of disease progression and cancer mortality.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Mahdi Sheikh, Shama Virani, Hilary A. Robbins, Lenka Foretova, Ivana Holcatova, Vladimir Janout, Jolanta Lissowska, Marie Navratilova, Anush Mukeriya, Miodrag Ognjanovic, Beata Swiatkowska, David Zaridze, Paul Brennan
Summary: This study investigated the survival and prognostic factors of surgically-resected early-stage non-small cell lung cancer (NSCLC) in Central and Eastern Europe. The 5-year survival rate was 49.5%, and age, gender, weight loss, smoking, alcohol drinking, and tumor stage were associated with the risk of death. Smoking and alcohol drinking showed a dose-dependent association with cancer-specific mortality.
Article
Oncology
Hana Zahed, Xiaoshuang Feng, Mahdi Sheikh, Freddie Bray, Jacques Ferlay, Ophira Ginsburg, Meredith S. Shiels, Hilary A. Robbins
Summary: This study examined the median age at diagnosis of common cancers worldwide and found that there are differences across countries. These differences likely arise from variations in risk factors and cancer control measures at the population level.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Elham Khodayari Moez, Matthew T. Warkentin, Yonathan Brhane, Stephen Lam, John K. Field, Geoffrey Liu, Javier J. Zulueta, Karmele Valencia, Miguel Mesa-Guzman, Andrea Pasquier Nialet, Sukhinder Atkar-Khattra, Michael P. A. Davies, Benjamin Grant, Kiera Murison, Luis M. Montuenga, Christopher Amos, Hilary A. Robbins, Mattias Johansson, Rayjean J. Hung
Summary: The study found that circulating protein markers can help differentiate malignant from benign pulmonary nodules. Using blood samples from international low-dose computed tomography screening studies, 36 potential protein markers were identified. The protein burden scores for overall nodule malignancy and imminent tumors were summarized, with a focus on the significantly higher scores for malignant nodules in LungRADS category 4. However, further validation is needed before clinical implementation.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
