Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension

Dissecting the human immunologic memory for pathogens

(2011) Christina E. Zielinski et al.   IMMUNOLOGICAL REVIEWS

Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection

(2010) Laurent Hocqueloux et al.   AIDS

Impact of Viral Dose and Major Histocompatibility Complex Class IB Haplotype on Viral Outcome in Mauritian Cynomolgus Monkeys Vaccinated with Tat upon Challenge with Simian/Human Immunodeficiency Virus SHIV89.6P

(2010) A. Cafaro et al.   JOURNAL OF VIROLOGY

Innate immunity against HIV: a priority target for HIV prevention research

(2010) Persephone Borrow et al.   Retrovirology

Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

(2010) Mark G Lewis et al.   Retrovirology

Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion

(2010) Olivier Bourry et al.   Retrovirology

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies

(2009) Laurence Colin et al.   Retrovirology

"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence

(2009) Andrea Savarino et al.   Retrovirology

Auranofin inhibits overproduction of pro-inflammatory cytokines, cyclooxygenase expression and PGE2 production in macrophages

(2008) Shinha Han et al.   ARCHIVES OF PHARMACAL RESEARCH

The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation

(2008) Andrew G. Cox et al.   BIOCHEMICAL PHARMACOLOGY

Auranofin promotes retinoic acid- or dihydroxyvitamin D3-mediated cell differentiation of promyelocytic leukaemia cells by increasing histone acetylation

(2008) S J Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gold(I) complexes determine apoptosis with limited oxidative stress in Jurkat T cells

(2008) Maria Pia Rigobello et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Phenotypic classification of human CD4+ T cell subsets and their differentiation

(2008) R. Okada et al.   INTERNATIONAL IMMUNOLOGY