Article
Immunology
Ethan Klock, Ethan Wilson, Reinaldo E. Fernandez, Estelle Piwowar-Manning, Ayana Moore, Barry Kosloff, Justin Bwalya, Nomtha Bell-Mandla, Anelet James, Helen Ayles, Peter Bock, Deborah Donnell, Sarah Fidler, Richard Hayes, Susan H. Eshleman, Oliver Laeyendecker
Summary: Cross-sectional HIV incidence testing is important for estimating population-level HIV incidence and evaluating prevention interventions. In settings with high levels of viral suppression, different multi-assay algorithms for incidence estimation may provide accurate or underestimated results.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2021)
Article
Biology
Doug Morrison, Oliver Laeyendecker, Ron Brookmeyer
Summary: The study introduces a method for generalized linear regression with interval-censored covariates, which indirectly infers the distribution of the covariate of interest compared to other conventional approaches. The proposed method shows less bias but slight increases in standard error when compared to midpoint analysis and uniform imputation methods.
Article
Mathematical & Computational Biology
Fei Gao, Marlena Bannick
Summary: Longitudinal cohorts for studying HIV infection incidence are difficult to implement, thus researchers have developed alternative strategies based on recency test methods. This article presents a theoretical framework, simulation study, and data analysis to evaluate the performance of two commonly used estimators for HIV incidence estimation. The findings provide recommendations for practical use of these estimators and discuss future methodological developments.
STATISTICS IN MEDICINE
(2022)
Review
Public, Environmental & Occupational Health
Shelley N. Facente, Eduard Grebe, Andrew D. Maher, Douglas Fox, Susan Scheer, Mary Mahy, Shona Dalal, David Lowrance, Kimberly Marsh
Summary: HIV recency assays have been validated for accurately estimating HIV incidence in specific populations at national and subnational levels; however, there is a lack of evidence validating the accuracy and effectiveness of using these assays to identify epidemic trends in non-incidence surveillance use cases. More research is needed to validate the use of recency assays within HIV testing services.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2022)
Article
Medicine, General & Internal
Stanley W. Wanjala, Moses K. Nyongesa, Paul Mwangi, Agnes M. Mutua, Stanley Luchters, Charles R. J. C. Newton, Amina Abubakar
Summary: This study examined HIV-related stigma among adults living with HIV on the Kenyan coast. The 12-item short version of the Berger HIV stigma scale showed high reliability and validity in measuring HIV stigma. The study found that being female, non-disclosure of HIV status, and co-occurrence of depressive and anxiety symptoms were significant predictors of HIV-related stigma.
Article
Medicine, General & Internal
Mary Kagujje, Paul Somwe, Sisa Hatwiinda, Joel Bwalya, Tamala Zgambo, Moomba Thornicroft, Fiammetta Maria Bozzani, Clement Moonga, Monde Muyoyeta
Summary: The study found high prevalence of tuberculosis and HIV in Zambian correctional facilities, highlighting the need for strengthening TB and HIV programs, especially tailored for juveniles and gender-specific initiatives.
Article
Public, Environmental & Occupational Health
Ling Zhang, Hang Yu, Hong Luo, Wenlong Rong, Xianxin Meng, Xiaoan Du, Xiaodong Tan
Summary: This study evaluated college students' understanding and attitudes towards HIV-infected patients, as well as the factors associated with their knowledge levels. Findings showed that knowledge levels were influenced by gender, nationality, marital status, and grade. Female and minority students had insufficient HIV health education knowledge, while male students and those with good HIV knowledge were more likely to hold positive attitudes towards HIV-infected patients. The study highlights the need for strengthened education efforts and the elimination of social discrimination against HIV-infected patients.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Tafadzwa Dhokotera, Julia Bohlius, Matthias Egger, Adrian Spoerri, Jabulani Ronnie Ncayiyana, Gita Naidu, Victor Olago, Marcel Zwahlen, Elvira Singh, Mazvita Muchengeti
Summary: This study aimed to determine the spectrum of cancers in adolescents and young adults living with and without HIV in South Africa. The results showed that young people living with HIV were more likely to have certain types of cancers compared to those without HIV.
Article
Multidisciplinary Sciences
Md. Tariqujjaman, Md. Mehedi Hasan, Mohammad Abdullah Heel Kafi, Md. Alamgir Hossain, Saad Khan, Nadia Sultana, Rashidul Azad, Md. Arif Hossain, Mahfuzur Rahman, Mohammad Bellal Hossain
Summary: The proportion of low HIV knowledge among ever-married women of reproductive age in Bangladesh has decreased from 1996 to 2014, although it still remains high. Prevention of early marriage, inclusion of HIV-related topics in the curriculum, and reducing urban-rural and wealth disparities may help improve HIV knowledge among ever-married Bangladeshi women.
Article
Medicine, General & Internal
Katherine Davis, Louisa Moorhouse, Rufurwokuda Maswera, Phyllis Mandizvidza, Tawanda Dadirai, Tafadzwa Museka, Constance Nyamukapa, Mikaela Smit, Simon Gregson
Summary: This study aimed to investigate the association between HIV status and antiretroviral therapy (ART) exposure with self-reported hypertension in Zimbabwe. The findings revealed no significant association between HIV status or ART exposure and self-reported hypertension.
Article
Infectious Diseases
Wendy Grant-McAuley, Oliver Laeyendecker, Daniel Monaco, Athena Chen, Sarah E. Hudelson, Ethan Klock, Ron Brookmeyer, Douglas Morrison, Estelle Piwowar-Manning, Charles S. Morrison, Richard Hayes, Helen Ayles, Peter Bock, Barry Kosloff, Kwame Shanaube, Nomtha Mandla, Anneen van Deventer, Ingo Ruczinski, Kai Kammers, H. Benjamin Larman, Susan H. Eshleman
Summary: This study evaluated the performance of two multi-assay algorithms (MAAs) that do not include viral load (VL) in estimating HIV incidence. The results showed that the MAAs without VL overestimated the incidence and performed poorly in classifying some long-term infected individuals as recently infected.
BMC INFECTIOUS DISEASES
(2022)
Article
Psychology, Clinical
Khunsa Junaid, Hassan Ali, Ali Akram Khan, Taimoor Akram Khan, Aabish Mehreen Khan, Amjad Khan, Rabia Nazim, Khadija Tahira
Summary: The prevalence of depression among HIV/AIDS patients in Pakistan is very high at 32.2%. Factors such as living in rural areas, fear of stigma and discrimination, having worked abroad, and history of substance abuse are significantly associated with depression in this population. It is recommended that guidelines be implemented to screen and treat depression among HIV patients in Pakistan.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2021)
Article
Geriatrics & Gerontology
Meilian Xie, Aiping Wang, Kerong Wang, Yanping Yu, Zhaoxia Lin
Summary: There is a debate regarding the impact of HIV duration on symptom distress among people living with HIV (PLWH), particularly among middle-aged and older individuals. This study found that PLWH with a duration of 6-10 years reported a higher burden of physical and psychological symptoms.
Article
Medicine, General & Internal
Marion Mora, Giovanna Rincon, Michel Bourrelly, Gwenaelle Maradan, Anaenza Freire Maresca, Florence Michard, Elisabeth Rouveix, Julie Pannetier, Diane Leriche, Tristan Alain, Yazdan Yazdanpanah, David Michels, Bruno Spire
Summary: Transgender identity faces low acceptance in France with scarce data available, leading to increased stigmatization and potential burden of HIV infection among TRHIV. ANRS Trans&HIV aims to identify vulnerabilities, obstacles in medical care, and gender affirmation/HIV care needs of TRHIV through a comprehensive national survey.
Article
Medicine, General & Internal
Yi Li, Fenglin Zhang, Zhengdong Dou, Wei Zheng, Ping Ai, Ming Bao, Congming Han, Kexia Xiang, Qirong Qin
Summary: This study investigated sexual behaviors among HIV-discordant heterosexual couples and found that couples with longer marital duration were more inclined to use condoms, while lack of support, remarriage, and being HIV-positive were associated with less condom use. In addition, HIV-positive individuals were more likely to engage in extramarital sex.
Article
Immunology
Charles S. Morrison, Rick Homan, Natasha Mack, Pairin Seepolmuang, Megan Averill, Jamilah Taylor, Jennifer Osborn, Peter Dailey, Neil Parkin, Stefano Ongarello, Timothy D. Mastro
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2017)
Editorial Material
Multidisciplinary Sciences
Willard Cates, Quarraisha Abdool Karim, Wafaa El-Sadr, Debra W. Haffner, Gladys Kalema-Zikusoka, Khama Rogo, Tricia Petruney, E. Megan Davidson Averill
Letter
Multidisciplinary Sciences
Willard Cates, E. Megan Davidson Averill, Tricia Petruney
Letter
Multidisciplinary Sciences
RM Cook-Deegan, R Berkelman, EM Davidson, S Finder, E Heitman, MC Keeley, NMP King, R Moseley, JC Thomas, SJ Tilden, NM Vangsnes
