Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS

Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing

(2018) Vittoria Cenni et al.   AGEING RESEARCH REVIEWS

Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disorders

(2016) Camilla Evangelisti et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Repression of the Antioxidant NRF2 Pathway in Premature Aging

(2016) Nard Kubben et al.   CELL

Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage

(2016) Ansar Karimian et al.   DNA REPAIR

MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: role of Hsp90 acetylation

(2016) Simona Panella et al.   Future Medicinal Chemistry

Cellular Senescence as the Causal Nexus of Aging

(2016) Naina Bhatia-Dey et al.   Frontiers in Genetics

Rapamycin treatment of Mandibuloacral Dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamics

(2016) Vittoria Cenni et al.   Aging-US

Nuclear membrane diversity: underlying tissue-specific pathologies in disease?

(2015) Howard J Worman et al.   CURRENT OPINION IN CELL BIOLOGY

HDAC2 Selectively Regulates FOXO3a-Mediated Gene Transcription during Oxidative Stress-Induced Neuronal Cell Death

(2015) S. Peng et al.   JOURNAL OF NEUROSCIENCE

TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation

(2015) Dzmitry G. Batrakou et al.   PLoS One

Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope

(2015) Shang-Yi A. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype

(2015) Camilla Pellegrini et al.   Oncotarget

Dual mTORC1/C2 inhibitors suppress cellular geroconversion (a senescence program)

(2015) Olga V. Leontieva et al.   Oncotarget

Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis

(2014) Fu-Ju Tian et al.   CARDIOVASCULAR RESEARCH

Emerin and histone deacetylase 3 (HDAC3) cooperatively regulate expression and nuclear positions of MyoD, Myf5, and Pax7 genes during myogenesis

(2013) Justin Demmerle et al.   CHROMOSOME RESEARCH

Lamins are rapamycin targets that impact human longevity: a study in centenarians

(2013) G. Lattanzi et al.   JOURNAL OF CELL SCIENCE

Nuclear lamins

(2013) Eivind Lund et al.   Nucleus

Prelamin A-mediated nuclear envelope dynamics in normal and laminopathic cells: Figure 1

(2011) Giovanna Lattanzi   BIOCHEMICAL SOCIETY TRANSACTIONS

Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle

(2011) E Mattioli et al.   CELL DEATH AND DIFFERENTIATION

An EDMD Mutation in C. elegans Lamin Blocks Muscle-Specific Gene Relocation and Compromises Muscle Integrity

(2011) Anna Mattout et al.   CURRENT BIOLOGY

A new pathway that regulates 53BP1 stability implicates Cathepsin L and vitamin D in DNA repair

(2011) Ignacio Gonzalez-Suarez et al.   EMBO JOURNAL

Aberrant Regulation of HDAC2 Mediates Proliferation of Hepatocellular Carcinoma Cells by Deregulating Expression of G1/S Cell Cycle Proteins

(2011) Ji Heon Noh et al.   PLoS One

Multiple roles of the cell cycle inhibitor p21CDKN1A in the DNA damage response

(2010) Ornella Cazzalini et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

A-type nuclear lamins act as transcriptional repressors when targeted to promoters

(2009) Damian C. Lee et al.   EXPERIMENTAL CELL RESEARCH

Atypical Progeroid Syndrome due to Heterozygous MissenseLMNAMutations

(2009) Abhimanyu Garg et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Suppression of Proliferative Defects Associated with Processing-defective Lamin A Mutants by hTERT or Inactivation of p53

(2008) Brian A. Kudlow et al.   MOLECULAR BIOLOGY OF THE CELL

Drugs affecting prelamin A processing: Effects on heterochromatin organization

(2007) Elisabetta Mattioli et al.   EXPERIMENTAL CELL RESEARCH