Methionine restriction slows down senescence in human diploid fibroblasts

Methionine Restriction Activates the Retrograde Response and Confers Both Stress Tolerance and Lifespan Extension to Yeast, Mouse and Human Cells

(2014) Jay E. Johnson et al.   PLoS One

Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification

(2014) Christoph Ruckenstuhl et al.   PLoS Genetics

Caloric restriction may reverse age-related autonomic decline in humans

(2012) Phyllis K. Stein et al.   AGING CELL

Effect of mtDNA point mutations on cellular bioenergetics

(2012) Joanna Szczepanowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Nonsense mutations in the COX1 subunit impair the stability of respiratory chain complexes rather than their assembly

(2012) Hue-Tran Hornig-Do et al.   EMBO JOURNAL

Glutathionylation State of Uncoupling Protein-2 and the Control of Glucose-stimulated Insulin Secretion

(2012) Ryan J. Mailloux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins

(2012) Ryan J. Mailloux et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

Dietary Methionine Restriction Increases Fat Oxidation in Obese Adults with Metabolic Syndrome

(2011) Eric P. Plaisance et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states

(2010) Barbara E. Hasek et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Role of β-adrenergic receptors in the hyperphagic and hypermetabolic responses to dietary methionine restriction

(2010) Eric P. Plaisance et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Novel insights into the assembly and function of human nuclear-encoded cytochromecoxidase subunits 4, 5a, 6a, 7a and 7b

(2010) Daniela Fornuskova et al.   BIOCHEMICAL JOURNAL

Detection and manipulation of mitochondrial reactive oxygen species in mammalian cells

(2010) Marleen Forkink et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cellular senescence: putting the paradoxes in perspective

(2010) Judith Campisi   CURRENT OPINION IN GENETICS & DEVELOPMENT

Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats

(2010) Carmen E. Perrone et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Caloric restriction: From soup to nuts

(2009) Stephen R. Spindler   AGEING RESEARCH REVIEWS

Role of nuclear-encoded subunit Vb in the assembly and stability of cytochromecoxidase complex: implications in mitochondrial dysfunction and ROS production

(2009) Domenico Galati et al.   BIOCHEMICAL JOURNAL

The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells

(2009) Barbara Lener et al.   BIOCHEMICAL JOURNAL

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age

(2009) L. Sun et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila

(2009) Richard C. Grandison et al.   NATURE

Forty Percent Methionine Restriction Decreases Mitochondrial Oxygen Radical Production and Leak at Complex I During Forward Electron Flow and Lowers Oxidative Damage to Proteins and Mitochondrial DNA in Rat Kidney and Brain Mitochondria

(2009) Pilar Caro et al.   REJUVENATION RESEARCH

Lowered methionine ingestion as responsible for the decrease in rodent mitochondrial oxidative stress in protein and dietary restriction

(2008) Mónica López-Torres et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Forty percent and eighty percent methionine restriction decrease mitochondrial ROS generation and oxidative stress in rat liver

(2008) Pilar Caro et al.   BIOGERONTOLOGY

Age-associated mosaic respiratory chain deficiency causes trans-neuronal degeneration

(2008) E. Dufour et al.   HUMAN MOLECULAR GENETICS

On Methionine Restriction, Suppression of Mitochondrial Dysfunction and Aging

(2008) Alan R. Hipkiss   REJUVENATION RESEARCH