Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan
出版年份 2014 全文链接
标题
Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan
作者
关键词
-
出版物
AGING CELL
Volume 13, Issue 5, Pages 911-917
出版商
Wiley
发表日期
2014-07-25
DOI
10.1111/acel.12256
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive
- (2013) Dudley W. Lamming et al. AGING CELL
- Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
- (2013) Richard A. Miller et al. AGING CELL
- Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2)
- (2013) Dudley W. Lamming et al. FASEB JOURNAL
- Haploinsufficiency of Akt1 Prolongs the Lifespan of Mice
- (2013) Aika Nojima et al. PLoS One
- mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin
- (2013) S. A. Kang et al. SCIENCE
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c
- (2012) Asami Hagiwara et al. Cell Metabolism
- TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO
- (2012) Stacey Robida-Stubbs et al. Cell Metabolism
- Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2
- (2012) Minsheng Yuan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Therapeutic Trial of Metformin and Bortezomib in a Mouse Model of Tuberous Sclerosis Complex (TSC)
- (2012) Neil Auricchio et al. PLoS One
- Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
- (2012) D. W. Lamming et al. SCIENCE
- Chronic Activation of mTOR Complex 1 Is Sufficient to Cause Hepatocellular Carcinoma in Mice
- (2012) S. Menon et al. Science Signaling
- Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis
- (2011) Francis X. McCormack et al. NEW ENGLAND JOURNAL OF MEDICINE
- Replication of Extended Lifespan Phenotype in Mice with Deletion of Insulin Receptor Substrate 1
- (2011) Colin Selman et al. PLoS One
- Sirolimus Therapy Predisposes to New-Onset Diabetes Mellitus After Renal Transplantation: A Long-Term Analysis of Various Treatment Regimens
- (2011) E. Gyurus et al. TRANSPLANTATION PROCEEDINGS
- Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
- (2010) Ivana Bjedov et al. Cell Metabolism
- Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue
- (2010) V. P. Houde et al. DIABETES
- Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
- (2010) Richard A. Miller et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
- (2010) Shomit Sengupta et al. NATURE
- mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice
- (2009) David A. Guertin et al. CANCER CELL
- Estrogens Protect against High-Fat Diet-Induced Insulin Resistance and Glucose Intolerance in Mice
- (2009) Elodie Riant et al. ENDOCRINOLOGY
- Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
- (2009) A. A. Soukas et al. GENES & DEVELOPMENT
- Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
- (2009) C. Selman et al. SCIENCE
- Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling
- (2008) Tsuneo Ikenoue et al. EMBO JOURNAL
- Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
- (2007) Colin Selman et al. FASEB JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now