Diacylglycerol lipaseregulates lifespan and oxidative stress response by inversely modulating TOR signaling inDrosophilaandC. elegans

 -6 Polyunsaturated fatty acids extend life span through the activation of autophagy

(2013) E. J. O'Rourke et al.   GENES & DEVELOPMENT

Phosphatidic acid and lipid-sensing by mTOR

(2013) David A. Foster   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The mystery of C. elegans aging: An emerging role for fat

(2012) Daniel Ackerman et al.   BIOESSAYS

Diacylglycerol Activation of Protein Kinase Cε and Hepatic Insulin Resistance

(2012) François R. Jornayvaz et al.   Cell Metabolism

Lessons from C. elegans: signaling pathways for longevity

(2012) Louis R. Lapierre et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Escherichia coli noncoding RNAs can affect gene expression and physiology of Caenorhabditis elegans

(2012) Huijie Liu et al.   Nature Communications

Reduced neuronal expression of ribose-5-phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity inDrosophila

(2011) Ching-Tzu Wang et al.   AGING CELL

New genes that extend Caenorhabditis elegans’ lifespan in response to reproductive signals

(2011) Mark McCormick et al.   AGING CELL

Interplay between FOXO, TOR, and Akt

(2011) Nissim Hay   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Death and dessert: nutrient signalling pathways and ageing

(2011) Nazif Alic et al.   CURRENT OPINION IN CELL BIOLOGY

Obesity and nutrient sensing TOR pathway in flies and vertebrates: Functional conservation of genetic mechanisms

(2011) Sean Oldham   TRENDS IN ENDOCRINOLOGY AND METABOLISM

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging

(2010) Pankaj Kapahi et al.   Cell Metabolism

A Tale of Tailless

(2010) Hongxing Gui et al.   DEVELOPMENTAL NEUROSCIENCE

The Aging Stress Response

(2010) Marcia C. Haigis et al.   MOLECULAR CELL

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reduced expression ofalpha-1,2-mannosidase Iextends lifespan inDrosophila melanogasterandCaenorhabditis elegans

(2009) Ya-Lin Liu et al.   AGING CELL

The TOR pathway comes of age

(2009) Monique N. Stanfel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Diacylglycerol kinases as sources of phosphatidic acid

(2009) Jinjin Cai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Regulation of Drosophila TRPC channels by lipid messengers

(2009) Padinjat Raghu et al.   CELL CALCIUM

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Diacylglycerol kinase regulation of protein kinase D during oxidative stress-induced intestinal cell injury

(2008) Jun Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The effect of neuronal expression of heat shock proteins 26 and 27 on lifespan, neurodegeneration, and apoptosis in Drosophila

(2008) Pin-Chao Liao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY

DAG Lipase Activity Is Necessary for TRP Channel Regulation in Drosophila Photoreceptors

(2008) Hung-Tat Leung et al.   NEURON

Diacylglycerol kinases: at the hub of cell signalling

(2007) Isabel Mérida et al.   BIOCHEMICAL JOURNAL

Protein kinase C activity is associated with prefrontal cortical decline in aging

(2007) Avis R. Brennan et al.   NEUROBIOLOGY OF AGING