Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence

Adult-onset, short-term dietary restriction reduces cell senescence in mice

(2016) Chunfang Wang et al.   Aging-US

AMPK Promotes p53 Acetylation via Phosphorylation and Inactivation of SIRT1 in Liver Cancer Cells

(2012) C.-W. Lee et al.   CANCER RESEARCH

Mouse models of growth hormone action and aging: A proteomic perspective

(2012) Juan Ding et al.   PROTEOMICS

Suppression of AMPK Activation via S485 Phosphorylation by IGF-I during Hyperglycemia Is Mediated by AKT Activation in Vascular Smooth Muscle Cells

(2011) Junyu Ning et al.   ENDOCRINOLOGY

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Small Is Beautiful: Insulin-Like Growth Factors and Their Role in Growth, Development, and Cancer

(2010) Robert G. Maki   JOURNAL OF CLINICAL ONCOLOGY

Mitochondrial Dysfunction Contributes to Oncogene-Induced Senescence

(2009) O. Moiseeva et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Paracrine Overexpression of Insulin-Like Growth Factor-1 Enhances Mammary Tumorigenesis in Vivo

(2008) Krisztina Kovács de Ostrovich et al.   AMERICAN JOURNAL OF PATHOLOGY

Free radicals and senescence

(2008) Teng Lu et al.   EXPERIMENTAL CELL RESEARCH

DBC1 is a negative regulator of SIRT1

(2008) Ja-Eun Kim et al.   NATURE

Many roads lead to oncogene-induced senescence

(2008) S Courtois-Cox et al.   ONCOGENE

SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts

(2008) Jing Huang et al.   PLoS One

Functionally significant insulin-like growth factor I receptor mutations in centenarians

(2008) Y. Suh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA