Longevity effect of IGF-1R+/−mutation depends on genetic background-specific receptor activation

Skeletal Muscle Growth Hormone Receptor Signaling Regulates Basal, but Not Fasting-Induced, Lipid Oxidation

(2012) Archana Vijayakumar et al.   PLoS One

Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains

(2012) R. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary restriction in rats and mice: A meta-analysis and review of the evidence for genotype-dependent effects on lifespan

(2011) William R. Swindell   AGEING RESEARCH REVIEWS

High fat diet induced insulin resistance and glucose intolerance are gender-specific in IGF-1R heterozygous mice

(2011) Neha Garg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Replication of Extended Lifespan Phenotype in Mice with Deletion of Insulin Receptor Substrate 1

(2011) Colin Selman et al.   PLoS One

Liver-Derived IGF-I Regulates Mean Life Span in Mice

(2011) Johan Svensson et al.   PLoS One

Does Reduced IGF-1R Signaling in Igf1r+/− Mice Alter Aging?

(2011) Alex F. Bokov et al.   PLoS One

Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains

(2010) Magalie S. Leduc et al.   AGING CELL

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

(2010) Mette Soerensen et al.   AGING CELL

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples

(2010) J. Xu et al.   JOURNAL OF ENDOCRINOLOGY

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Lifespan extension in genetically modified mice

(2009) Warren Ladiges et al.   AGING CELL

Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels

(2009) Rong Yuan et al.   AGING CELL

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

(2009) Ludmila Pawlikowska et al.   AGING CELL

Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

(2009) Chen-Yu Liao et al.   AGING CELL

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations

(2009) Yang Li et al.   HUMAN MOLECULAR GENETICS

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

(2009) D. J. Waxman et al.   MOLECULAR PHARMACOLOGY

Association ofFOXO3Avariation with human longevity confirmed in German centenarians

(2009) Friederike Flachsbart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Early Postnatal Nutrition Determines Somatotropic Function in Mice

(2008) Laurent Kappeler et al.   ENDOCRINOLOGY

Role of the GH/IGF-1 axis in lifespan and healthspan: Lessons from animal models

(2008) Darlene E. Berryman et al.   GROWTH HORMONE & IGF RESEARCH

Neuronal Death by Oxidative Stress Involves Activation of FOXO3 through a Two-Arm Pathway That Activates Stress Kinases and Attenuates Insulin-like Growth Factor I Signaling

(2008) David Dávila et al.   MOLECULAR BIOLOGY OF THE CELL

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functionally significant insulin-like growth factor I receptor mutations in centenarians

(2008) Y. Suh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Response to Comment on "Brain IRS2 Signaling Coordinates Life Span and Nutrient Homeostasis"

(2008) A. Taguchi et al.   SCIENCE

Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism

(2008) Laurent Kappeler et al.   PLOS BIOLOGY

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

(2007) Colin Selman et al.   FASEB JOURNAL