High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan

CDC25A: A Rebel Within the CDC25 Phosphatases Family?

(2012) Anne Fernandez-Vidal et al.   Anti-Cancer Agents in Medicinal Chemistry

The Role of Cdc25A in the Regulation of Cell Proliferation and Apoptosis

(2012) Tao Shen et al.   Anti-Cancer Agents in Medicinal Chemistry

MicroRNAs and their roles in aging

(2012) T. Smith-Vikos et al.   JOURNAL OF CELL SCIENCE

High expression of miR-21 in tumor stroma correlates with increased cancer cell proliferation in human breast cancer

(2011) LENE RASK et al.   APMIS

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

(2011) Emma Raitoharju et al.   ATHEROSCLEROSIS

Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21

(2011) Pierre E. Queiroz de Oliveira et al.   CELL CYCLE

Inflammation regulates microRNA expression in cooperation with p53 and nitric oxide

(2011) Ewy Mathé et al.   INTERNATIONAL JOURNAL OF CANCER

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Identification of evolutionarily conserved genetic regulators of cellular aging

(2010) Gerhard T. Laschober et al.   AGING CELL

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

(2010) Matthias Hackl et al.   AGING CELL

MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration

(2010) Joy Sarkar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

(2010) Martina Weber et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Short Communication: Asymmetric Dimethylarginine Impairs Angiogenic Progenitor Cell Function in Patients With Coronary Artery Disease Through a MicroRNA-21–Dependent Mechanism

(2010) Felix Fleissner et al.   CIRCULATION RESEARCH

MicroRNA-21: From Cancer to Cardiovascular Disease

(2010) Virginija Jazbutyte et al.   CURRENT DRUG TARGETS

Novel modulators of senescence, aging, and longevity: Small non-coding RNAs enter the stage

(2010) Johannes Grillari et al.   EXPERIMENTAL GERONTOLOGY

8-Methoxypsoralen Plus Ultraviolet A Therapy Acts via Inhibition of the IL-23/Th17 Axis and Induction of Foxp3+ Regulatory T Cells Involving CTLA4 Signaling in a Psoriasis-Like Skin Disorder

(2010) T. P. Singh et al.   JOURNAL OF IMMUNOLOGY

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

(2010) Pedro P. Medina et al.   NATURE

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Hypoxia and RAS-signaling pathways converge on and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs

(2010) F Loayza-Puch et al.   ONCOGENE

microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells

(2009) P. Wang et al.   CANCER RESEARCH

Involvement of MicroRNAs in Hydrogen Peroxide-mediated Gene Regulation and Cellular Injury Response in Vascular Smooth Muscle Cells

(2009) Ying Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA Expression Signature and the Role of MicroRNA-21 in the Early Phase of Acute Myocardial Infarction

(2009) Shimin Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 protects against the H2O2-induced injury on cardiac myocytes via its target gene PDCD4

(2009) Yunhui Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

How Does Proliferative Homeostasis Change With Age? What Causes It and How Does It Contribute to Aging?

(2009) J. Campisi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Vascular endothelial senescence: from mechanisms to pathophysiology

(2008) Jorge D. Erusalimsky   JOURNAL OF APPLIED PHYSIOLOGY

miR-21 Gene Expression Triggered by AP-1 Is Sustained through a Double-Negative Feedback Mechanism

(2008) Shuji Fujita et al.   JOURNAL OF MOLECULAR BIOLOGY