Targeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain

Comparison of Next-Generation Sequencing Systems

(2012) Lin Liu et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

(2012) Christoph Freyer et al.   NATURE GENETICS

Mitochondrial Mutations and Polymorphisms in Psychiatric Disorders

(2012) Adolfo Sequeira et al.   Frontiers in Genetics

Evaluation of a Droplet Digital Polymerase Chain Reaction Format for DNA Copy Number Quantification

(2011) Leonardo B. Pinheiro et al.   ANALYTICAL CHEMISTRY

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

Mitochondrial DNA and disease

(2011) Laura C Greaves et al.   JOURNAL OF PATHOLOGY

The timing of mitochondrial DNA mutations in aging

(2011) Konstantin Khrapko   NATURE GENETICS

Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations

(2011) Brendan A I Payne et al.   NATURE GENETICS

Replication Pauses of the Wild-Type and Mutant Mitochondrial DNA Polymerase Gamma: A Simulation Study

(2011) Zhuo Song et al.   PLoS Computational Biology

Ultra-Deep Sequencing of Mouse Mitochondrial DNA: Mutational Patterns and Their Origins

(2011) Adam Ameur et al.   PLoS Genetics

Somatic mutations of mitochondrial DNA in aging and cancer progression

(2010) Hsin-Chen Lee et al.   AGEING RESEARCH REVIEWS

Mitochondrial DNA deletions in mice in men: Substantia nigra is much less affected in the mouse

(2010) Xinhong Guo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial DNA deletion mutations in patients with neuropsychiatric symptoms

(2010) Maiko Kato et al.   NEUROSCIENCE RESEARCH

On the timing and the extent of clonal expansion of mtDNA deletions: Evidence from single-molecule PCR

(2009) Alexander Nicholas et al.   EXPERIMENTAL NEUROLOGY

How Is Mutant Mitochondrial DNA Clonally Amplified? Much New Evidence, Still No Answers

(2009) Aubrey D.N.J. de Grey   REJUVENATION RESEARCH

The 4977bp deletion of mitochondrial DNA in human skeletal muscle, heart and different areas of the brain: A useful biomarker or more?

(2008) Christoph Meissner et al.   EXPERIMENTAL GERONTOLOGY

Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons

(2008) Hirokazu Fukui et al.   HUMAN MOLECULAR GENETICS

Quantification of random mutations in the mitochondrial genome

(2008) Marc Vermulst et al.   METHODS

Single molecule PCR in mtDNA mutational analysis: Genuine mutations vs. damage bypass-derived artifacts

(2008) Y. Kraytsberg et al.   METHODS

What causes mitochondrial DNA deletions in human cells?

(2008) Kim J Krishnan et al.   NATURE GENETICS

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice

(2008) Marc Vermulst et al.   NATURE GENETICS

Mitochondrial DNA mutations and aging: devils in the details?

(2008) Konstantin Khrapko et al.   TRENDS IN GENETICS