Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan

A Prospective Study of High-Density Lipoprotein Cholesterol, Cholesteryl Ester Transfer Protein Gene Variants, and Healthy Aging in Very Old Japanese-American Men

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Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies

(2010) Rune Jacobsen et al.   AGING CELL

A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

(2010) Anne B. Newman et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context

(2010) Alexander M. Kulminski et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Selection on Alleles Affecting Human Longevity and Late-Life Disease: The Example of Apolipoprotein E

(2010) Fotios Drenos et al.   PLoS One

Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity

(2010) M. Beekman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trade-Offs Between Cancer and Other Diseases: Do They Exist and Influence Longevity?

(2010) Svetlana V. Ukraintseva et al.   REJUVENATION RESEARCH

Prospects for Life Span Extension

(2009) Felipe Sierra et al.   Annual Review of Medicine

Apolipoprotein E and its role in aging and survival

(2009) Francesca Bonomini et al.   EXPERIMENTAL GERONTOLOGY

Mortality, Dementia, and Apolipoprotein E Genotype in Elderly White Women in the United States

(2009) Deborah M. Little et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

APOLIPOPROTEIN E, DEMENTIA, AND HUMAN LONGEVITY

(2009) Francesco Panza et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

Common disorders are quantitative traits

(2009) Robert Plomin et al.   NATURE REVIEWS GENETICS

Decanalization and the origin of complex disease

(2009) Greg Gibson   NATURE REVIEWS GENETICS

Common Genetic Variation and Human Traits

(2009) David B. Goldstein   NEW ENGLAND JOURNAL OF MEDICINE

Evolution of the human lifespan and diseases of aging: Roles of infection, inflammation, and nutrition

(2009) C. E. Finch   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association ofFOXO3Avariation with human longevity confirmed in German centenarians

(2009) Friederike Flachsbart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shifting Paradigm of Association Studies: Value of Rare Single-Nucleotide Polymorphisms

(2008) Ivan P. Gorlov et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Signaling networks in aging

(2008) Eric L. Greer et al.   JOURNAL OF CELL SCIENCE

Apolipoprotein E-polymorphism, frailty and mortality in older adults

(2008) Kenneth Rockwood et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Impact of apoE genotype on oxidative stress, inflammation and disease risk

(2008) Laia Jofre-Monseny et al.   MOLECULAR NUTRITION & FOOD RESEARCH

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA