Article
Medicine, Research & Experimental
Maryam Fallah, Amirhossein Davoodvandi, Shahin Nikmanzar, Sarehnaz Aghili, Seyed Mohammad Ali Mirazimi, Michael Aschner, Amir Rashidian, Michael R. Hamblin, Mohsen Chamanara, Navid Naghsh, Hamed Mirzaei
Summary: Silymarin, extracted from milk thistle, has hepatoprotective, anti-cancer, and anti-inflammatory properties. It may reduce side effects and enhance anti-cancer effects in chemotherapy and radiotherapy.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Chemistry, Medicinal
Ekaterina D. Obluchinskaya, Olga N. Pozharitskaya, Elena V. Flisyuk, Alexander N. Shikov
Summary: The study developed and optimized a fucoidan-based cream formulation with high stability and good release efficiency, showing promising anti-inflammatory potential in in vivo experiments.
Article
Dermatology
Clara Gibielle, Lydia Bousseksou, Sabine Guehenneux, Katell Vie
Summary: This study investigated the anti-aging potential of a cream containing Harungana madagascariensis plant extract. The results showed that this cream can improve wrinkles, sagging, color uniformity, smoothness, plumpness, firmness, and elasticity of the facial skin. The effects of this cream are comparable to a retinol cream. Further research is needed to confirm these findings.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Thalita Marcolan Valverde, Bruna Nayane Goncalves de Souza Soares, Andrea Mendes do Nascimento, angela Leao Andrade, Lucas Resende Dutra Sousa, Paula Melo de Abreu Vieira, Vagner Rodrigues Santos, Janaina Brandao Seibert, Tatiane Cristine Silva de Almeida, Caio Fabrini Rodrigues, Samantha Roberta Machado de Oliveira, Flaviano dos Santos Martins, Jeronimo Geraldo Ferreira Junior, Viviane Martins Rebello dos Santos
Summary: Propolis is a natural substance with various biological activities, including antiviral, antibacterial, antifungal, anti-inflammatory, immunoregulatory, antioxidant, and wound healing properties. It has garnered attention in the pharmaceutical and cosmetic industries for its potential applications, particularly in the areas of antioxidant and anti-inflammatory activities. Studies have shown that propolis exhibits high antioxidant activity and can act as a broad-spectrum sun protector against UVB and UVA radiation. The extract of red propolis obtained through ethanolic extraction showed positive results for flavonoids and terpenoids, as well as effective antioxidant and antibacterial activities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Yanxia Liu, Minghuo Wu, Miaomiao Ren, Haijun Bao, Qing'an Wang, Nan Wang, Shibo Sun, Jianqiang Xu, Xiaojing Yang, Xu Zhao, Yongming Bao, Gaohong He, Weiping Xu
Summary: This study aims to develop a fermented milk containing silybin and protein from milk thistle seeds. A three-step procedure was developed, including homogenization of seeds, NaHCO3 heat treatment, and microbial fermentation. The fermented milk had high yields of silybin and protein, making it a potential dietary supplement.
Article
Dermatology
Ahmed A. H. Abdellatif, Sulaiman Hamad Alawadh, Abdellatif Bouazzaoui, Ahmad H. Alhowail, Hamdoon A. Mohammed
Summary: The study demonstrates that pomegranate anthocyanins formulation can effectively reduce skin aging, with non-irritating and good permeation properties, making it a safe and effective anti-aging drug formulation.
JOURNAL OF DERMATOLOGICAL TREATMENT
(2021)
Article
Dentistry, Oral Surgery & Medicine
Yuriy Nekrashevych, Anton Schestakow, Wiebke Hoth-Hannig, Matthias Hannig
Summary: The study found that treating the acquired enamel pellicle with milk or cream during formation in situ does not enhance its protective potential against erosion. There were no significant differences in erosive surface alterations between pellicles treated with cream or milk compared to control pellicles.
JOURNAL OF DENTISTRY
(2021)
Article
Food Science & Technology
Kiran Verma, Ayon Tarafdar, Deepak Kumar, Yogesh Kumar, Jogender Singh Rana, Prarabdh C. Badgujar
Summary: In this study, a novel nano-curcumin enriched milk cream powder was formulated using microfluidization and spray drying techniques. The results showed that the formulation using sodium caseinate for spray drying had higher yield and encapsulation efficiency, and smaller particle size. The fluorescence properties and morphology further confirmed the efficiency of encapsulation. The in vitro bioaccessibility study demonstrated high curcumin bioaccessibility and inhibition of HepG2 cells, without cytotoxicity. The cream spread made from the powder showed high sensory acceptability, indicating the applicability of the formulation.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Pharmacology & Pharmacy
Baraa Maulood Ahmed Al-dabbagh, Mohammed N. Abed, Nadia Mohammed Mahmood, Fawaz A. Alassaf, Mahmood H. M. Jasim, Mohanad Alfahad, Imad A. -J Thanoon
Summary: The study aimed to evaluate the hepatoprotective properties of a pharmaceutically formulated milk thistle on liver disease recovery in diabetic female albino rats, as well as its antidiabetic activity. The results indicated that the treatment with milk thistle could successfully achieve the therapeutic target, repair the damage to hepatic cells caused by diabetes, and improve the diabetic status.
LATIN AMERICAN JOURNAL OF PHARMACY
(2022)
Article
Engineering, Chemical
Ana Margarida Silva, Paulo C. Costa, Cristina Delerue-Matos, Francisca Rodrigues
Summary: The study evaluated the effect of a formulation containing chestnut shell extract on human volunteers, showing a slight reduction in wrinkles and roughness but no significant difference compared to the placebo in the short term. However, the formulation significantly improved skin hydration and increased skin firmness in some volunteers. Long-term use of the product is recommended to observe significant differences in all parameters.
Article
Pharmacology & Pharmacy
Nur Ain Omar, Fashli Syafiq Abd Razak, Cher Hing Tang, A. B. M. Helal Uddin, Md Zaidul Islam Sarker, Ashok Kumar Janakiraman, Kai Bin Liew
Summary: The study aimed to formulate and optimize a cosmetic cream containing Annona muricata extract. Results showed that cream with 2%, 5%, and 10% extract exhibited antioxidant activity and physical stability, making it a potential antioxidant cosmetic cream to be marketed in the future.
LATIN AMERICAN JOURNAL OF PHARMACY
(2021)
Article
Plant Sciences
Mohamed A. O. Abdelfattah, Malak Dmirieh, Widad Ben Bakrim, Omar Mouhtady, Mosad A. Ghareeb, Michael Wink, Mansour Sobeh
Summary: Warburgia is a widely distributed genus that possesses anti-inflammatory and antioxidant properties. This study found that an extract from Warburgia bark has significant antioxidant and anti-aging effects, making it a valuable source of bioactive compounds.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Alexe Grenier, Jean Legault, Andre Pichette, Lorry Jean, Audrey Belanger, Roxane Pouliot
Summary: The study evaluated the safety and anti-aging efficacy of a Kalmia angustifolia extract using reconstructed skin substitutes, demonstrating strong antioxidant and anti-inflammatory activities. The extract increased dermal thickness and enhanced elastin and collagen-1 expression, suggesting promising antioxidant efficacy and anti-aging potential.
Article
Food Science & Technology
Akang Dan, Yushi Chen, Yongqi Tian, Shaoyun Wang
Summary: The study aimed to explore the potential of the fungus Paecilomyces hepiali as a foodborne antioxidant and anti-aging agent. The n-butanol extract from rice cultures showed significant antioxidant activity and prolonged the lifespan of Drosophila on a high-fat diet. Further research revealed the presence of dimerumic acid as the major antioxidant compound in PHE.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Article
Agriculture, Dairy & Animal Science
Wiktor Bendowski, Monika Michalczuk, Artur Jozwik, Karwan Yaseen Kareem, Andrzej Lozicki, Jakub Karwacki, Damian Bien
Summary: The study aimed to investigate the effects of milk thistle on the welfare, production results, physicochemical properties, enzyme activity, and antioxidant potential of broiler chickens, showing significant impacts on growth performance, antioxidant capacity, and welfare.