Article
Biotechnology & Applied Microbiology
Ikki Horiguchi, Hotaka Nagate, Yasuyuki Sakai
Summary: This study used a particle-tracking-based strategy to optimize agitation conditions for shaking suspension culture of iPSCs. The results showed that orbital shaking provided the most stable high acceleration, and the number of dead cells correlated with the average time of acceleration. These findings suggest that image-based analyses of aggregates can help optimize agitation conditions for iPSC culture.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
(2023)
Article
Physics, Multidisciplinary
M. Muhsin, F. Adersh, M. Sahoo
Summary: The dynamics of a charged inertial active Ornstein-Uhlenbeck particle in viscoelastic suspension is studied. The steady state response of a confined harmonic particle to a magnetic field is found to exhibit interesting features due to the interplay of elastic dissipation and active fluctuations. The steady state MSD is enhanced or suppressed with increasing magnetic field strength depending on the relative time scales of activity, elastic dissipation, and memory in the medium.
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS
(2023)
Article
Mechanics
James T. Jenkins, Ryohei Seto, Luigi La Ragione
Summary: The study analyzes the extensional flows of a dense layer of spheres in a viscous fluid by using force and torque balances to determine the trajectory of particle pairs. It investigates the relationship between stress, microstructure, and strain rate, and shows that this relation involves the second and fourth moments of the particle distribution function.
JOURNAL OF FLUID MECHANICS
(2021)
Article
Chemistry, Physical
Mariah J. J. Gallegos, Diego D. D. Soetrisno, Nayoung Park, Jacinta C. C. Conrad
Summary: We present a colloid-polymer model system with adjustable bridging interactions for microscopic studies of structure and dynamics using con focal imaging. By controlling the polymer concentration and pH, we can tune the interactions between trifluoroethyl methacrylate-co-tert-butyl methacrylate copolymer particles and poly(acrylic acid) (PAA) polymers. The strength of PAA adsorption on the particles, which is driven by pH dependent interactions with polymer brush stabilizers on the particle surfaces, can be adjusted via solution pH. The ability to visualize the suspension structure provides insight into the role of polymer-driven bridging interactions in colloidal suspensions.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Biochemical Research Methods
Tetsuro Tsuji, Satoshi Taguchi, Hiroki Takamatsu
Summary: This study experimentally investigates the significance of thermophoresis and thermal convection on particle transport in a heated liquid phase by changing the gap size. Results show a threshold gap size where particles accumulate around the heated spot above the threshold, forming a ring-like distribution, while below the threshold particles are depleted from the spot. Switching between accumulation and depletion modes may lead to novel manipulation techniques.
Article
Physics, Fluids & Plasmas
M. Muhsin, M. Sahoo, Arnab Saha
Summary: In this study, the behavior of a self-propelling particle in a viscoelastic fluid under the influence of a magnetic field is examined. It is found that the system's classical orbital magnetism is dependent on the presence of inertia, and the system can transition between diamagnetic and paramagnetic states by adjusting the timescales of active fluctuations and viscoelastic dissipation. Additionally, the magnetic moment of the system, which disappears at equilibrium, exhibits nonmonotonic behavior with increasing persistence of self-propulsion.
Article
Chemistry, Multidisciplinary
Aliaa I. Shallan, Yakini Tavares, Moein Navvab Kashani, Michael C. Breadmore, Craig Priest
Summary: The study developed a continuous in situ sampler that can extract particle-free solution from a turbulent high solids content stream without needing to be close to a solid surface. Two applications were demonstrated: monitoring Fe-III in a stirred slurry of mixed ore particles and dissolution profiles of paracetamol tablets with different formulations.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Engineering, Biomedical
Isamu Ogawa, Daichi Onozato, Shiho Anno, Hisato Hayashi, Tatsuro Kanaki, Takahiro Iwao, Tamihide Matsunaga
Summary: This study proposes a new culture method for human induced pluripotent stem cell-derived intestinal organoids (HIOs) using low concentrations of natural polysaccharides in a suspension culture. The HIOs cultured in this method showed similarities to living intestines and exhibited pharmacokinetic functions. This method can be widely applied to drug discovery, disease research, and regenerative medicine, overcoming challenges in traditional culture methods.
Article
Chemistry, Physical
Pietro Binel, Ankit Jain, Anna Jaeggi, Daniel Biri, Ashwin Kumar Rajagopalan, Andrew J. deMello, Marco Mazzotti
Summary: Characterization of particle size and shape is crucial for the study of particulate matter. This study focuses on micrometer-sized cuboidal particles and develops a methodology to completely describe their size and shape using three orthogonal dimensions. An online and in-flow multiprojection imaging tool coupled with machine learning is experimentally assessed, and analytical standards of user-defined size and shape are fabricated using photolithography. The results show that this imaging tool can not only measure particle sizing, but also estimate particle orientation in flow, providing a rapid and robust protocol for investigating the behavior of dilute particle-laden flows.
Article
Engineering, Chemical
Kevin P. Galvin
Summary: The transition from a carbon to a metals-based economy is driving an unprecedented demand for minerals, posing a challenging process engineering task due to decreasing ore grade and environmental concerns. Recent developments with the Reflux Classifier show potential for significant improvements in separation efficiency and processing speed by applying new forces to enhance selectivity.
CHEMICAL ENGINEERING SCIENCE
(2021)
Article
Construction & Building Technology
Amir Boulbair, Ahmed Benabed, Bart Janssens, Karim Limam, Walter Bosschaerts
Summary: This study numerically investigated particle resuspension induced by walking, showing that the resuspension fraction increases with particle size and walking speed. However, no significant influence of shoe groove patterns was observed.
BUILDING AND ENVIRONMENT
(2022)
Article
Mechanics
Enzu Zheng, Murray Rudman, Shibo Kuang, Andrew Chryss
Summary: This paper investigates the interaction between non-Newtonian carrier and coarse particles in high concentration tailings suspension, presenting a DNS-DEM model validated with experiments. Results show that the presence of concentrated particles weakens turbulence in the pipeline, affecting particle resuspension.
INTERNATIONAL JOURNAL OF MULTIPHASE FLOW
(2021)
Article
Nanoscience & Nanotechnology
Mengfei Huang, Yuan Liu, Zahra Khalkhali, Ara Kim, Weiguo Hu, Jae-Hwang Lee, Jonathan P. Rothstein, John Klier, Jessica D. Schiffman
Summary: Epoxy-encapsulated microparticles with core-shell structures synthesized via suspension polymerization enable high-efficiency, room-temperature cold spray processing. Microparticles with pure resin cores exhibit the lowest viscosity and highest deposition efficiency.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biotechnology & Applied Microbiology
Asher Kahn-Krell, Danielle Pretorius, Jianfa Ou, Vladimir G. Fast, Silvio Litovsky, Joel Berry, Xiaoguang (Margaret) Liu, Jianyi Zhang
Summary: A protocol for differentiating suspensions of hiPSC spheroids into cardiomyocytes based on the GiWi method is introduced, and after optimization, the purity of hiPSC-CMs exceeded 98% with yields of about 1.5 million hiPSC-CMs per mL and less between-batch purity variability than hiPSC-CMs produced in 2D cultures. Additionally, the culture volume could be increased up to 10-fold to 30 mL with no need for re-optimization, suggesting that this method can serve as a framework for large-scale hiPSC-CM production.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Engineering, Civil
Yunsheng Li, Xu Zhang, Can Wang, Yanling Zhang, Xinxin Wei
Summary: This study investigated the dynamic behavior of a newly-built glass suspension bridge. The results showed that the bridge had low vertical natural frequencies, resulting in resonance under walking and running tests. The study also revealed that the modal parameter features of the glass-bottomed footbridge were different from conventional ones.
STRUCTURE AND INFRASTRUCTURE ENGINEERING
(2023)
Article
Chemistry, Analytical
Alexander L. Kovach, Randi R. Carter, Jonathan W. Thornburg, Robert Wiethe, Timothy R. Fennell, Jenny L. Wiley
Summary: Studies have found that vitamin E acetate undergoes thermal degradation in electronic vaping devices and is considered a major contributor to e-cigarette or vaping product use-associated lung injuries. By analyzing the degradation products of vitamin E acetate, researchers have identified two major compounds and suggested their potential as biomarkers for exposure and toxicity assessment.
JOURNAL OF ANALYTICAL TOXICOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Geunwoo Oh, Hyunwook Park, Jung-Il Choi
Summary: This study derives correlations between the drag, lift, and torque coefficients and the axis ratio and angle of attack for elliptic cylinders. The correlations are simple functions based on variations in these parameters. Numerical simulations are performed to calculate the hydrodynamic forces, and a critical Reynolds number map is obtained. The proposed correlations accurately predict the hydrodynamic forces in Stokes to laminar flow regimes, even when using simple basic forms.
Article
Thermodynamics
Jinho Ha, Yun Young Choi, Youngkwon Kim, Je-Nam Lee, Jung-Il Choi
Summary: A two-layer hydrodynamic network model is proposed to analyze the distribution of electrolyte in a redox flow battery. The model consists of a channel, a porous electrode, and an inter-connection part. Using the Hardy-Cross method, the flow rate and pressure drop of each component are calculated. The model has shown good agreement with experimental and CFD results.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2023)
Article
Engineering, Chemical
Geunwoo Oh, Yesol Hyun, Jung-Il Choi, Jaeheon Lee, Min-Kun Kim, Heesoo Jung
Summary: We conducted computational fluid dynamics (CFD) simulations to predict the breakthrough times of planar-shaped air-purifying respirator (APR) canisters with various internal shapes. The simulations demonstrated the validity of the adsorption process modeling based on backward differentiation formulas. The breakthrough time was found to be more related to the maximum flow speed inside the filter rather than the local mean air age.
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2023)
Article
Computer Science, Interdisciplinary Applications
Tiantian Xu, Jung-Il Choi
Summary: Efficient monolithic immersed boundary projection methods with staggered time discretization were proposed for incompressible viscous flows with heat transfer. The main idea is to use a two-step approximate lower-upper decomposition technique to decouple the momentum and energy equations, including immersed boundary forcing. Various MIBPM variants based on forcing schemes were numerically evaluated. The proposed MIBPM presents accurate imposition of no-slip conditions and exhibits good stability for both two-dimensional and three-dimensional heat transfer flows over moving objects.
JOURNAL OF COMPUTATIONAL PHYSICS
(2023)
Article
Construction & Building Technology
Mingyu Yang, Geunwoo Oh, Tiantian Xu, Jungwoo Kim, Ji-Hoon Kang, Jung-Il Choi
Summary: This study presents an innovative real-time urban microclimate simulation strategy using a large-eddy simulation (LES) solver deployed on a multi-GPU architecture. The study successfully captures the complexity of urban geometries by utilizing a building-resolved, wall-modeled LES augmented by an immersed boundary method. The simulation results efficiently highlight variations in wind patterns with altitude, demonstrating its potential to provide useful wind information for pedestrian-level wind comfort assessment and urban air mobility.
BUILDING AND ENVIRONMENT
(2023)
Article
Computer Science, Interdisciplinary Applications
Mingyu Yang, Ji-Hoon Kang, Ki-Ha Kim, Oh-Kyoung Kwon, Jung-Il Choi
Summary: We introduce an updated library, PaScaL_TDMA 2.0, which is capable of exploiting multi-GPU environments. The library extends its functionality to include GPU support and minimizes CPU-GPU data transfer by utilizing device-resident memory while retaining the original CPU-based capabilities. The library employs pipeline copying with shared memory for low-latency memory access and incorporates CUDA-aware MPI for efficient multi-GPU communication. Our GPU implementation demonstrated outstanding computational performance compared to the original CPU implementation while consuming much less energy.
COMPUTER PHYSICS COMMUNICATIONS
(2023)
Article
Computer Science, Interdisciplinary Applications
Ki-Ha Kim, Ji-Hoon Kang, Xiaomin Pan, Jung-Il Choi
Summary: PaScaL_TCS is an efficient and scalable solver for large-scale direct numerical simulations of natural convective flow that considers temperature-dependent fluid properties. The solver decomposes the computational domain into a cubic sub-domain for increased scalability on a massive-scale distributed memory system. It uses the monolithic projection method with staggered time discretization and solves batched tridiagonal systems using the PaScaL_TDMA library. Two transpose schemes with different communicator sizes are proposed and compared for parallel fast Fourier transform. An explicit intermediate aggregation scheme for MPI-IO is suggested to reduce the number of processes involved in parallel IO. The solver demonstrates good strong and weak scalability up to 131,072 cores and is verified through simulations of differentially heated vertical convection flow and glycerol Rayleigh-Benard convection flow.
COMPUTER PHYSICS COMMUNICATIONS
(2023)
Article
Mechanics
Xiaomin Pan, Jung-Il Choi
Summary: In this study, the non-Oberbeck-Boussinesq (NOB) effects in three representative fluids in two-dimensional Rayleigh-Benard convection were quantitatively investigated. It was found that the temperature and velocity profiles were top-bottom antisymmetric under NOB conditions. The time-averaged temperature of the cavity center increased with increasing Prandtl number, and its value was weakly influenced by the Rayleigh number for all fluids. Furthermore, the NOB effects on various parameters such as the Nusselt number and thermal boundary layer thickness were relatively small for Pr = 0.71 and 4.4, but significant for Pr = 2547.
Article
Mechanics
Tiantian Xu, Jung-Il Choi
Summary: This study proposes a highly stable and efficient monolithic immersed boundary projection method for particle sedimentation with heat transfer. The method effectively couples fluid and solid motion and addresses stability and spurious oscillation issues. The investigation of the effects of particle sedimentation reveals a significant influence of buoyancy force on relatively lighter particles.
Article
Energy & Fuels
Seongyoon Kim, Sanghyun Kim, Yun Young Choi, Jung-Il Choi
Summary: This study proposes a comprehensive framework of Bayesian parameter identification for electrochemical models in lithium-ion batteries. It determines the parameter distributions and estimates the global sensitivity of the parameters. The framework can help to analyze the behaviors of batteries according to specific operating conditions and materials.
JOURNAL OF ENERGY STORAGE
(2023)
Article
Energy & Fuels
Seongyoon Kim, Hangsoon Jung, Minho Lee, Yun Young Choi, Jung-Il Choi
Summary: This study proposes a data-centric method to predict the capacity degradation trajectory of lithium-ion cells using early single-cycle data. A deep learning-based model is used to predict a few knots at specific retention levels, which are then interpolated to reconstruct the trajectory. The proposed method is effective in predicting capacity degradation trajectories and can help establish appropriate warranties or replacement cycles in the battery manufacturing and diagnosis processes.
Article
Engineering, Aerospace
Wanli Yu, Seungho Song, Tiantian Xu, Jung-Il Choi
Summary: In this study, a finite-volume-based 3D compressible flow solver was developed to simulate blast wave propagation after a high-energy explosion. The solver accounts for various initial conditions, real gas equations of state, and radiation heat transfer effects. The validation experiments include simulating weak- and strong-point explosions, shock-tube problems, and investigating the formation of a fireball after an explosion. The results indicate that considering real gas and radiation effects leads to lower peak overpressure and shock arrival time compared to the ideal gas assumption.
INTERNATIONAL JOURNAL OF AERONAUTICAL AND SPACE SCIENCES
(2023)
Article
Thermodynamics
Mingyu Yang, Seongyoon Kim, Xiang Sun, Sanghyun Kim, Jiyong Choi, Tae Seon Park, Jung-Il Choi
Summary: This study optimized the operating conditions of a recuperative burner system using computational fluid dynamics (CFD) and reduced-order deep learning technique, resulting in improved performance and reduced environmental pollution. The study employed CFD simulation and a genetic algorithm to find the optimal conditions for various objectives.
APPLIED THERMAL ENGINEERING
(2024)
Article
Energy & Fuels
Kyunghyun Kim, Jung-Il Choi
Summary: The overall performance of battery modules and the effect of different system structures and connection methods are evaluated in this study. The module with cross-contacting system terminal shows clear improvement in reducing cell-to-cell variation and enhancing safety. The proposed method can assist engineers in designing longer-lasting and more efficient energy storage systems.
